| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Riluzole hydrochloride perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Riluzole hydrochloride_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.229077 |
| COL6A3 | collagen, type VI, alpha 3 | 0.145203 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.133265 |
| PLEC | plectin | 0.118479 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.110233 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0937457 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0841807 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0760103 |
| COL5A1 | collagen, type V, alpha 1 | 0.0656704 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0638253 |
| RRM2 | ribonucleotide reductase M2 | 0.0573017 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0568062 |
| SMAD3 | SMAD family member 3 | 0.0566912 |
| TMSB10 | thymosin beta 10 | 0.0538325 |
| MSN | moesin | 0.0524912 |
| ACTG1 | actin gamma 1 | 0.0520052 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0508079 |
| FLNA | filamin A, alpha | 0.0503035 |
| DST | dystonin | 0.0499239 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0486425 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0471817 |
| NONO | non-POU domain containing, octamer-binding | 0.0457837 |
| MT2A | metallothionein 2A | 0.0456912 |
| SEPTIN9 | septin 9 | 0.0455028 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0454515 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | 0.0446307 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0437869 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0433594 |
| MLPH | melanophilin | 0.042818 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0425849 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0422759 |
| ACTN4 | actinin, alpha 4 | 0.0411013 |
| AXL | AXL receptor tyrosine kinase | 0.0409221 |
| CD44 | CD44 molecule (Indian blood group) | 0.0395447 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0391694 |
| VEGFA | vascular endothelial growth factor A | 0.0382739 |
| LDHA | lactate dehydrogenase A | 0.0379314 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0367697 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0365283 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0353105 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0338426 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0334954 |
| MAP1B | microtubule-associated protein 1B | 0.0330477 |
| DNMBP | dynamin binding protein | 0.0329758 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0325051 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0312112 |
| CENPF | centromere protein F, 350/400kDa | 0.0300732 |
| TNS1 | tensin 1 | 0.0299755 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0288297 |
| RPL3 | ribosomal protein L3 | 0.0288203 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0283741 |
| PODXL | podocalyxin-like | 0.0281262 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | 0.0274015 |
| HRNR | hornerin | 0.0264404 |
| ZNF185 | zinc finger protein 185 (LIM domain) | 0.0260202 |
| WWOX | WW domain containing oxidoreductase | 0.0258285 |
| GRAMD1B | GRAM domain containing 1B | 0.0258194 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0256025 |
| SON | SON DNA binding protein | 0.0255815 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0251373 |
| CD82 | CD82 molecule | 0.0249733 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0248353 |
| ACTN1 | actinin, alpha 1 | 0.0243271 |
| YBX1 | Y box binding protein 1 | 0.0238476 |
| HLA-B | major histocompatibility complex, class I, B | 0.0238039 |
| PFKP | phosphofructokinase, platelet | 0.023731 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0235397 |
| TPM3 | tropomyosin 3 | 0.0233714 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0233064 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0225958 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0225659 |
| NAV1 | neuron navigator 1 | 0.0223443 |
| LMNA | lamin A/C | 0.0222472 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0219864 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.021821 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0217727 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0217675 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0216475 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0215803 |
| CEP250 | centrosomal protein 250kDa | 0.0213283 |
| DBN1 | drebrin 1 | 0.0213266 |
| CALR | calreticulin | 0.0213145 |
| SET | SET nuclear proto-oncogene | 0.0212638 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0209343 |
| HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 | 0.0209091 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0208869 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0206157 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.020502 |
| TPI1 | triosephosphate isomerase 1 | 0.0204121 |
| MT1X | metallothionein 1X | 0.0201423 |
| ANGPTL4 | angiopoietin-like 4 | 0.0201368 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0200921 |
| FUS | FUS RNA binding protein | 0.0200772 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0197888 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) | 0.0197721 |
| H1-2 | H1.2 linker histone, cluster member | 0.01955 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.01915 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0189644 |
| TGM2 | transglutaminase 2 | 0.0184823 |
| FOSL1 | FOS-like antigen 1 | 0.0184218 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.393989 |
| VIM | vimentin | -0.245729 |
| FN1 | fibronectin 1 | -0.213886 |
| CDH13 | cadherin 13 | -0.13899 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.104179 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.100193 |
| ASPH | aspartate beta-hydroxylase | -0.0931987 |
| LOX | lysyl oxidase | -0.0905919 |
| IGF2 | insulin-like growth factor 2 | -0.0828794 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0772027 |
| HMGA2 | high mobility group AT-hook 2 | -0.0674676 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0601892 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0597235 |
| RAI14 | retinoic acid induced 14 | -0.0570285 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0544845 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0529191 |
| CCND1 | cyclin D1 | -0.0525905 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0520595 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0501217 |
| INHBA | inhibin, beta A | -0.0492839 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0470276 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0452899 |
| CANX | calnexin | -0.0451778 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0447924 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0434422 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0431237 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0426122 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0420174 |
| TMEM165 | transmembrane protein 165 | -0.0397765 |
| VCL | vinculin | -0.0397001 |
| EGR1 | early growth response 1 | -0.0396138 |
| GOLGA4 | golgin A4 | -0.0395431 |
| DTNA | dystrobrevin, alpha | -0.0395277 |
| UBC | ubiquitin C | -0.0393707 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.039254 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0389282 |
| MAP4 | microtubule-associated protein 4 | -0.038102 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0371439 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0368374 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0366555 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0365889 |
| SBF2 | SET binding factor 2 | -0.0363441 |
| PCBP3 | poly(rC) binding protein 3 | -0.0358049 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0354309 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0352694 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0352612 |
| IL1B | interleukin 1, beta | -0.035077 |
| FMN1 | formin 1 | -0.0347901 |
| PDE10A | phosphodiesterase 10A | -0.0345448 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0339483 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0336118 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0328275 |
| JMJD1C | jumonji domain containing 1C | -0.0325917 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0325567 |
| GNAS | GNAS complex locus | -0.0323536 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0323123 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0319872 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0310556 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0302158 |
| TMEM263 | transmembrane protein 263 | -0.0296855 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0294183 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0292398 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0290343 |
| FNIP1 | folliculin interacting protein 1 | -0.0289705 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0288061 |
| WASF2 | WAS protein family, member 2 | -0.0286255 |
| CDCP1 | CUB domain containing protein 1 | -0.028457 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0277641 |
| RTN4 | reticulon 4 | -0.0274265 |
| CLMP | CXADR-like membrane protein | -0.0271973 |
| COL1A1 | collagen, type I, alpha 1 | -0.0271514 |
| NUMB | numb homolog (Drosophila) | -0.0269766 |
| NABP1 | nucleic acid binding protein 1 | -0.0267876 |
| GLG1 | golgi glycoprotein 1 | -0.0267254 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0267021 |
| USP34 | ubiquitin specific peptidase 34 | -0.0266244 |
| SEC24A | SEC24 family member A | -0.025824 |
| CD109 | CD109 molecule | -0.0257432 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0255088 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0255034 |
| SEC24D | SEC24 family member D | -0.0253959 |
| SETD5 | SET domain containing 5 | -0.0252965 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0250089 |
| AHNAK | AHNAK nucleoprotein | -0.024734 |
| PTMA | prothymosin, alpha | -0.0247226 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0246016 |
| CUX1 | cut-like homeobox 1 | -0.0245635 |
| NAV2 | neuron navigator 2 | -0.0244246 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.0244071 |
| TENM2 | teneurin transmembrane protein 2 | -0.0243615 |
| ANTXR2 | anthrax toxin receptor 2 | -0.024332 |
| IER3 | immediate early response 3 | -0.0242502 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0240364 |
| FBXO11 | F-box protein 11 | -0.0240239 |
| MMP12 | matrix metallopeptidase 12 | -0.0240149 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0239071 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0236581 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0236572 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0236333 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.023313 |
