| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Riluzole hydrochloride perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Riluzole hydrochloride_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KRT8 | keratin 8, type II | 0.174204 |
| KRT18 | keratin 18, type I | 0.142609 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.121765 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0921261 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0895458 |
| SMAD3 | SMAD family member 3 | 0.0885862 |
| PLEC | plectin | 0.0789583 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0779468 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0757446 |
| VEGFA | vascular endothelial growth factor A | 0.0700926 |
| LMO7 | LIM domain 7 | 0.0645091 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0565669 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0507023 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0506256 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0476501 |
| RPL23 | ribosomal protein L23 | 0.0473341 |
| EPS8L1 | EPS8-like 1 | 0.0470622 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0459571 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0454183 |
| ANXA11 | annexin A11 | 0.0453141 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0438619 |
| NONO | non-POU domain containing, octamer-binding | 0.0437975 |
| RPL3 | ribosomal protein L3 | 0.0437396 |
| TNS1 | tensin 1 | 0.0398449 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0397218 |
| FTL | ferritin, light polypeptide | 0.0396247 |
| HYOU1 | hypoxia up-regulated 1 | 0.039512 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0390307 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0386928 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0384645 |
| PLK2 | polo-like kinase 2 | 0.0365042 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0364654 |
| TMSB10 | thymosin beta 10 | 0.0356557 |
| ARHGAP23 | Rho GTPase activating protein 23 | 0.0353937 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0342556 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.033937 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0333221 |
| ACTG1 | actin gamma 1 | 0.032922 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0325712 |
| LRATD2 | LRAT domain containing 2 | 0.0324952 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0324291 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0322027 |
| FAT1 | FAT atypical cadherin 1 | 0.0314622 |
| BCL2L1 | BCL2-like 1 | 0.030697 |
| BCL3 | B-cell CLL/lymphoma 3 | 0.0294397 |
| CTBP2 | C-terminal binding protein 2 | 0.0294035 |
| NTN4 | netrin 4 | 0.0293832 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.029205 |
| TRIB1 | tribbles pseudokinase 1 | 0.0289045 |
| HKDC1 | hexokinase domain containing 1 | 0.0279661 |
| CALR | calreticulin | 0.0275574 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.027345 |
| MLPH | melanophilin | 0.0265322 |
| PPL | periplakin | 0.0262089 |
| MYEOV | myeloma overexpressed | 0.025572 |
| RPL35A | ribosomal protein L35a | 0.0251965 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0248726 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.02445 |
| HDLBP | high density lipoprotein binding protein | 0.0242776 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | 0.0242171 |
| CCNYL1 | cyclin Y-like 1 | 0.0241096 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0239344 |
| MYO18A | myosin XVIIIA | 0.0238776 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0236129 |
| HSPA8 | heat shock 70kDa protein 8 | 0.023535 |
| RPS4X | ribosomal protein S4, X-linked | 0.023473 |
| JUN | jun proto-oncogene | 0.0234011 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0230902 |
| MYO5B | myosin VB | 0.023048 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0230479 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0228349 |
| CPNE1 | copine I | 0.0225186 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0224096 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.021916 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0218218 |
| PRELID3B | PRELI domain containing 3B | 0.0216204 |
| HLA-A | major histocompatibility complex, class I, A | 0.0214493 |
| MLLT6 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 | 0.0212893 |
| HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 | 0.0207768 |
| HLA-C | major histocompatibility complex, class I, C | 0.0207666 |
| B2M | beta-2-microglobulin | 0.0207491 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | 0.0205862 |
| RPL13A | ribosomal protein L13a | 0.0204373 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0204 |
| SLC45A4 | solute carrier family 45, member 4 | 0.0202823 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0202304 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0202013 |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 | 0.0200365 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0199003 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0197478 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0196638 |
| SEPTIN9 | septin 9 | 0.0196525 |
| STK40 | serine/threonine kinase 40 | 0.0196475 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0196183 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0194809 |
| MINK1 | misshapen-like kinase 1 | 0.0191564 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0190732 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0189542 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.0187232 |
| AGRN | agrin | 0.0186872 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | -0.14115 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0958595 |
| LYZ | lysozyme | -0.0902211 |
| ANXA2 | annexin A2 | -0.0785371 |
| NF1 | neurofibromin 1 | -0.0770136 |
| PTMA | prothymosin, alpha | -0.0741209 |
| JMJD1C | jumonji domain containing 1C | -0.0688704 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0686723 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0684154 |
| WASF2 | WAS protein family, member 2 | -0.0683166 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0640536 |
| GOLGA4 | golgin A4 | -0.0634173 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.063192 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0620129 |
| PTK2 | protein tyrosine kinase 2 | -0.0612875 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0599958 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0591292 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0582094 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0557115 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0539289 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0536013 |
| SBF2 | SET binding factor 2 | -0.0531222 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0530461 |
| COG5 | component of oligomeric golgi complex 5 | -0.0526901 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0523045 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0512882 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0509926 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0509056 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0503441 |
| CD2AP | CD2-associated protein | -0.0499084 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0497346 |
| ZNF292 | zinc finger protein 292 | -0.0497013 |
| RBM39 | RNA binding motif protein 39 | -0.0492239 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.047017 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0467085 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0447316 |
| USP34 | ubiquitin specific peptidase 34 | -0.0447267 |
| DIAPH2 | diaphanous-related formin 2 | -0.0442063 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.04405 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0439319 |
| RTN4 | reticulon 4 | -0.0433022 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.043095 |
| HMGA1 | high mobility group AT-hook 1 | -0.0430642 |
| DGKH | diacylglycerol kinase, eta | -0.0428139 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0419831 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0419022 |
| MKI67 | marker of proliferation Ki-67 | -0.0417788 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0417209 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.041617 |
| SQSTM1 | sequestosome 1 | -0.0415662 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0414949 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0412001 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0410986 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0408079 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0399503 |
| TMEM123 | transmembrane protein 123 | -0.0396938 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0393419 |
| RPS2 | ribosomal protein S2 | -0.0391038 |
| CDK13 | cyclin-dependent kinase 13 | -0.0388719 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0386137 |
| RTN3 | reticulon 3 | -0.0382758 |
| ZNF207 | zinc finger protein 207 | -0.0379206 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0377099 |
| CCNL1 | cyclin L1 | -0.0374735 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0374169 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0369048 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0368295 |
| FNIP1 | folliculin interacting protein 1 | -0.0365525 |
| BBX | bobby sox homolog (Drosophila) | -0.0364929 |
| VCL | vinculin | -0.0363638 |
| TOP1 | topoisomerase (DNA) I | -0.0362617 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0358229 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0354027 |
| ERBIN | erbb2 interacting protein | -0.0352428 |
| THOC2 | THO complex 2 | -0.0350885 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0350168 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0348191 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.034577 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0345429 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.034467 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0343104 |
| FAM135A | family with sequence similarity 135, member A | -0.0340679 |
| SPAG9 | sperm associated antigen 9 | -0.0338908 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0336304 |
| FRY | furry homolog (Drosophila) | -0.03354 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0332839 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0332404 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0326282 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0325741 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0324172 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0323097 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0322185 |
| IPO7 | importin 7 | -0.0320694 |
| MYO6 | myosin VI | -0.0319544 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0319309 |
| NBEAL1 | neurobeachin-like 1 | -0.0318714 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0317313 |
| ANLN | anillin, actin binding protein | -0.0316964 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0316715 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0315313 |
