| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Riluzole hydrochloride perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Riluzole hydrochloride_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.147398 |
| MT2A | metallothionein 2A | 0.107195 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.09873 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.09757 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.0859681 |
| DST | dystonin | 0.0830896 |
| TMSB10 | thymosin beta 10 | 0.0795309 |
| FRMD5 | FERM domain containing 5 | 0.0759824 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0703285 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0683944 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0661043 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0640684 |
| ASPH | aspartate beta-hydroxylase | 0.0606966 |
| KRT8 | keratin 8, type II | 0.0571503 |
| PEG3 | paternally expressed 3 | 0.0567301 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0544885 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0541212 |
| NHSL1 | NHS-like 1 | 0.0525202 |
| VEGFA | vascular endothelial growth factor A | 0.0517868 |
| FMNL2 | formin-like 2 | 0.0515436 |
| ATP10A | ATPase, class V, type 10A | 0.0497448 |
| IGF1R | insulin-like growth factor 1 receptor | 0.049056 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0483139 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0482561 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0476911 |
| RNF213 | ring finger protein 213 | 0.0472715 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0455193 |
| DSPP | dentin sialophosphoprotein | 0.0452182 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0433093 |
| TNS1 | tensin 1 | 0.0428685 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0416562 |
| KRT18 | keratin 18, type I | 0.0411979 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0406498 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0406221 |
| NDRG1 | N-myc downstream regulated 1 | 0.0398123 |
| RAD51B | RAD51 paralog B | 0.0395766 |
| CNKSR3 | CNKSR family member 3 | 0.0389955 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0388235 |
| ATXN1 | ataxin 1 | 0.0388101 |
| TBC1D22A | TBC1 domain family, member 22A | 0.038637 |
| LOC112694756 | uncharaterized LOC112694756 | 0.037714 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0364709 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.0363248 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0357853 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.035655 |
| CEP250 | centrosomal protein 250kDa | 0.0352085 |
| FOXP1 | forkhead box P1 | 0.0347621 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0343897 |
| CLTB | clathrin, light chain B | 0.0339642 |
| UTRN | utrophin | 0.0330271 |
| RPL3 | ribosomal protein L3 | 0.0330216 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0329631 |
| FAM107B | family with sequence similarity 107, member B | 0.0326075 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0323789 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0320016 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0315264 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0314943 |
| EHBP1 | EH domain binding protein 1 | 0.0313489 |
| APOE | apolipoprotein E | 0.0310505 |
| MSI2 | musashi RNA-binding protein 2 | 0.0309647 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0307823 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0289522 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0281715 |
| KYNU | kynureninase | 0.0281051 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0279538 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0275355 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0273312 |
| FAT1 | FAT atypical cadherin 1 | 0.0272078 |
| NONO | non-POU domain containing, octamer-binding | 0.0271633 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0270794 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0269529 |
| DOCK4 | dedicator of cytokinesis 4 | 0.026905 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0268322 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0266247 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0260529 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0259102 |
| MT1X | metallothionein 1X | 0.0258877 |
| COL27A1 | collagen, type XXVII, alpha 1 | 0.0255749 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.0255659 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.025489 |
| CALR | calreticulin | 0.0253154 |
| CCNY | cyclin Y | 0.0250407 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | 0.0244285 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0243685 |
| ADD3 | adducin 3 (gamma) | 0.0243576 |
| SMAD3 | SMAD family member 3 | 0.0242739 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0240906 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | 0.0239899 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.0239364 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0236023 |
| GSE1 | Gse1 coiled-coil protein | 0.0236018 |
| RNF216 | ring finger protein 216 | 0.0234923 |
| HDAC4 | histone deacetylase 4 | 0.0234599 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0234506 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0234347 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0233319 |
| MATN3 | matrilin 3 | 0.0233059 |
| PLEKHA7 | pleckstrin homology domain containing, family A member 7 | 0.0228456 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0226616 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0226563 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.338241 |
| APOB | apolipoprotein B | -0.228958 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.143525 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.133191 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.129232 |
| FN1 | fibronectin 1 | -0.115918 |
| ITGAV | integrin, alpha V | -0.089907 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | -0.0768109 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0680942 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.0630225 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0618657 |
| C3 | complement component 3 | -0.0589112 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0576313 |
| IGF2 | insulin-like growth factor 2 | -0.055996 |
| GPC3 | glypican 3 | -0.0536978 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0484774 |
| RPS8 | ribosomal protein S8 | -0.0480107 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0479494 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0458108 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0447807 |
| EGR1 | early growth response 1 | -0.0445544 |
| VCL | vinculin | -0.0441632 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0438683 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0425984 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0425375 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0415708 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0413676 |
| RPS12 | ribosomal protein S12 | -0.0410363 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0389134 |
| PHF3 | PHD finger protein 3 | -0.0386142 |
| YME1L1 | YME1-like 1 ATPase | -0.0384695 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0384154 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0380961 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0376781 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0376527 |
| RPLP1 | ribosomal protein, large, P1 | -0.0371634 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0363839 |
| MRTFA | myocardin related transcription factor A | -0.0363575 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0359198 |
| GOLGA4 | golgin A4 | -0.0354665 |
| VMP1 | vacuole membrane protein 1 | -0.0352666 |
| TRIM26 | tripartite motif containing 26 | -0.0351591 |
| JMJD1C | jumonji domain containing 1C | -0.0346806 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0344755 |
| RPL34 | ribosomal protein L34 | -0.0335173 |
| GDF15 | growth differentiation factor 15 | -0.0334616 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.033162 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0331586 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0331379 |
| RPL37A | ribosomal protein L37a | -0.0329164 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0327293 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0320367 |
| MBNL3 | muscleblind-like splicing regulator 3 | -0.0319842 |
| ZNF644 | zinc finger protein 644 | -0.031924 |
| RPS6 | ribosomal protein S6 | -0.0318903 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.031693 |
| DENND4A | DENN/MADD domain containing 4A | -0.0311915 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0309777 |
| RPS2 | ribosomal protein S2 | -0.0309238 |
| KIF5B | kinesin family member 5B | -0.0300736 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0297909 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0295681 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0295435 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0292749 |
| MYO1E | myosin IE | -0.0289575 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0289519 |
| RPS5 | ribosomal protein S5 | -0.0288963 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0286296 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0285501 |
| FAM135A | family with sequence similarity 135, member A | -0.0285086 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0284694 |
| PLIN2 | perilipin 2 | -0.0283975 |
| UBC | ubiquitin C | -0.0282225 |
| TOP1 | topoisomerase (DNA) I | -0.027964 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0278658 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0274427 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0273542 |
| A2M | alpha-2-macroglobulin | -0.0272723 |
| RBM25 | RNA binding motif protein 25 | -0.0272434 |
| SHOC2 | soc-2 suppressor of clear homolog (C. elegans) | -0.0271621 |
| RPL39 | ribosomal protein L39 | -0.0271588 |
| ARHGEF18 | Rho/Rac guanine nucleotide exchange factor (GEF) 18 | -0.0271034 |
| RPS14 | ribosomal protein S14 | -0.0269295 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | -0.0268696 |
| MED13L | mediator complex subunit 13-like | -0.026864 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0267321 |
| RPS20 | ribosomal protein S20 | -0.0267308 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0267047 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0264728 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0262541 |
| RPLP0 | ribosomal protein, large, P0 | -0.0256128 |
| ANXA5 | annexin A5 | -0.0255755 |
| PAPOLA | poly(A) polymerase alpha | -0.0253012 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0252324 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0251382 |
| HMGA1 | high mobility group AT-hook 1 | -0.0250987 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0249167 |
| TLK1 | tousled-like kinase 1 | -0.0249045 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0248854 |
| STK17A | serine/threonine kinase 17a | -0.0245148 |
