| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Riluzole hydrochloride perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Riluzole hydrochloride_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.476475 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.178826 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.136684 |
| PODXL | podocalyxin-like | 0.0853004 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0692767 |
| MSN | moesin | 0.0691083 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0681604 |
| FLNA | filamin A, alpha | 0.0596408 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0591222 |
| FOSL1 | FOS-like antigen 1 | 0.0572451 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.0560504 |
| HLA-C | major histocompatibility complex, class I, C | 0.0551629 |
| SET | SET nuclear proto-oncogene | 0.0542687 |
| BCL2L1 | BCL2-like 1 | 0.0540891 |
| LDHA | lactate dehydrogenase A | 0.0533826 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0520364 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.051969 |
| ACTG1 | actin gamma 1 | 0.0514306 |
| NONO | non-POU domain containing, octamer-binding | 0.0501804 |
| COL5A1 | collagen, type V, alpha 1 | 0.0499169 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0493306 |
| VEGFA | vascular endothelial growth factor A | 0.0486579 |
| CEP250 | centrosomal protein 250kDa | 0.0468223 |
| ACTN1 | actinin, alpha 1 | 0.0457177 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0449716 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0448948 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0440391 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0436071 |
| TPM3 | tropomyosin 3 | 0.0434387 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0430805 |
| KRT8 | keratin 8, type II | 0.0419057 |
| NAV2 | neuron navigator 2 | 0.0417242 |
| FLNB | filamin B, beta | 0.0402265 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0382603 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.036893 |
| AXL | AXL receptor tyrosine kinase | 0.0364193 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0341292 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0339956 |
| YBX1 | Y box binding protein 1 | 0.0339771 |
| CPNE1 | copine I | 0.0339215 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0332724 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0330861 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0330617 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0327416 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0322847 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0321693 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0313933 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.031349 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0313485 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0313282 |
| CALR | calreticulin | 0.0308223 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0307009 |
| PLEC | plectin | 0.0304094 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0299917 |
| TMSB4X | thymosin beta 4, X-linked | 0.029971 |
| ZNF148 | zinc finger protein 148 | 0.0298855 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0289478 |
| PFKP | phosphofructokinase, platelet | 0.0285711 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0280368 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0276491 |
| ERBIN | erbb2 interacting protein | 0.0271855 |
| RLIM | ring finger protein, LIM domain interacting | 0.0270467 |
| TXNRD1 | thioredoxin reductase 1 | 0.0269249 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0263269 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0261826 |
| FRMD6 | FERM domain containing 6 | 0.0260869 |
| ANKRD36 | ankyrin repeat domain 36 | 0.025926 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0256554 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0256001 |
| SMAD3 | SMAD family member 3 | 0.0252965 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0252675 |
| DST | dystonin | 0.0248824 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0248759 |
| KPNB1 | karyopherin (importin) beta 1 | 0.024323 |
| NAV1 | neuron navigator 1 | 0.0237127 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0231404 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.022918 |
| ZNF841 | zinc finger protein 841 | 0.0227283 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0225843 |
| EEFSEC | eukaryotic elongation factor, selenocysteine-tRNA-specific | 0.0224692 |
| RPL3 | ribosomal protein L3 | 0.0223789 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0222916 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0222481 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0218134 |
| HYOU1 | hypoxia up-regulated 1 | 0.0216074 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0215763 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0213662 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0213567 |
| POTEF | POTE ankyrin domain family, member F | 0.0213412 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0208993 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0208769 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0208629 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0207874 |
| DIDO1 | death inducer-obliterator 1 | 0.0206331 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.020598 |
| CENPF | centromere protein F, 350/400kDa | 0.0203402 |
| PCBP2 | poly(rC) binding protein 2 | 0.0201139 |
| SETX | senataxin | 0.0197593 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0197576 |
| DBN1 | drebrin 1 | 0.0194151 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.265808 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.180466 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.160372 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.109565 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0977159 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.07655 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0678045 |
| INTS6 | integrator complex subunit 6 | -0.0661908 |
| GLIS3 | GLIS family zinc finger 3 | -0.0650808 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0581625 |
| DEK | DEK proto-oncogene | -0.055823 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0539961 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0508882 |
| ASPH | aspartate beta-hydroxylase | -0.050315 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.048096 |
| TLE4 | transducin-like enhancer of split 4 | -0.0471321 |
| RAI14 | retinoic acid induced 14 | -0.046617 |
| GNAS | GNAS complex locus | -0.0431497 |
| FTL | ferritin, light polypeptide | -0.0426734 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0418097 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0396522 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0368193 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0344424 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0335041 |
| MAP4 | microtubule-associated protein 4 | -0.033362 |
| CCND1 | cyclin D1 | -0.0332057 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0328752 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0322785 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0318161 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0305556 |
| AHNAK | AHNAK nucleoprotein | -0.0297005 |
| PTMA | prothymosin, alpha | -0.0296799 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0287061 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0281776 |
| RTN3 | reticulon 3 | -0.0279861 |
| HMGB1 | high mobility group box 1 | -0.027516 |
| POSTN | periostin, osteoblast specific factor | -0.0272482 |
| RPL26 | ribosomal protein L26 | -0.027069 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0263235 |
| TKT | transketolase | -0.0260258 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0259873 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0254166 |
| HLA-B | major histocompatibility complex, class I, B | -0.02516 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0250522 |
| ITGA1 | integrin, alpha 1 | -0.0244744 |
| IER3 | immediate early response 3 | -0.0242643 |
| ZNF804A | zinc finger protein 804A | -0.0241405 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -0.023487 |
| NDRG1 | N-myc downstream regulated 1 | -0.0233974 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0232475 |
| RPL34 | ribosomal protein L34 | -0.0230694 |
| MT2A | metallothionein 2A | -0.022979 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0227526 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0224107 |
| SBF2 | SET binding factor 2 | -0.0223702 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.022361 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0222911 |
| COL3A1 | collagen, type III, alpha 1 | -0.0221723 |
| SULF1 | sulfatase 1 | -0.0221621 |
| SQSTM1 | sequestosome 1 | -0.0221329 |
| ADAM32 | ADAM metallopeptidase domain 32 | -0.0218502 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0216641 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0216631 |
| DTNA | dystrobrevin, alpha | -0.0215814 |
| RPLP2 | ribosomal protein, large, P2 | -0.0212474 |
| RPL32 | ribosomal protein L32 | -0.0209864 |
| RPL12 | ribosomal protein L12 | -0.0209659 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0209516 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa | -0.0208464 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0206694 |
| SNX14 | sorting nexin 14 | -0.0205628 |
| CUL4B | cullin 4B | -0.0205007 |
| CAVIN1 | caveolae associated protein 1 | -0.0202823 |
| MTDH | metadherin | -0.020229 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0201526 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0201179 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.019993 |
| WASF2 | WAS protein family, member 2 | -0.0196697 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0196498 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0192471 |
| LOX | lysyl oxidase | -0.0191623 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0190113 |
| RPS24 | ribosomal protein S24 | -0.0190042 |
| S100A10 | S100 calcium binding protein A10 | -0.0187639 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0186469 |
| VIM | vimentin | -0.0184792 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0183039 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0181858 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0181607 |
| DIAPH2 | diaphanous-related formin 2 | -0.0181527 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0180512 |
| DIPK2A | divergent protein kinase domain 2A | -0.0179243 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0179163 |
| RPL35A | ribosomal protein L35a | -0.0178033 |
| FRMD4A | FERM domain containing 4A | -0.0177491 |
| RBM39 | RNA binding motif protein 39 | -0.0176788 |
| DENND1A | DENN/MADD domain containing 1A | -0.0174633 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0174141 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0172978 |
| AEBP2 | AE binding protein 2 | -0.0172918 |
