| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Riluzole hydrochloride perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Riluzole hydrochloride_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.201537 |
| TMSB4X | thymosin beta 4, X-linked | 0.168121 |
| DST | dystonin | 0.144458 |
| HLA-B | major histocompatibility complex, class I, B | 0.100532 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0964894 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0959597 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0956393 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0952436 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0931066 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0912041 |
| PLEC | plectin | 0.0787511 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0707545 |
| MT1X | metallothionein 1X | 0.0703057 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0683657 |
| CAPRIN2 | caprin family member 2 | 0.0663973 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.0604993 |
| MT1E | metallothionein 1E | 0.0598429 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0567667 |
| HLA-C | major histocompatibility complex, class I, C | 0.0559101 |
| TMSB10 | thymosin beta 10 | 0.0549447 |
| EZR | ezrin | 0.0547958 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0543014 |
| NONO | non-POU domain containing, octamer-binding | 0.0530803 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0526597 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0524313 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0495438 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0491463 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.047828 |
| ACTG1 | actin gamma 1 | 0.047641 |
| CEP250 | centrosomal protein 250kDa | 0.0444638 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0440323 |
| JUN | jun proto-oncogene | 0.0425652 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0418721 |
| VCL | vinculin | 0.0416631 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0408007 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.040575 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0402505 |
| ANGPTL4 | angiopoietin-like 4 | 0.0392574 |
| SDC4 | syndecan 4 | 0.0387389 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.038705 |
| UBC | ubiquitin C | 0.0383995 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0375234 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0368368 |
| RPL37 | ribosomal protein L37 | 0.0360805 |
| ACTN1 | actinin, alpha 1 | 0.0360757 |
| RPL3 | ribosomal protein L3 | 0.0353318 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0351756 |
| ENO1 | enolase 1, (alpha) | 0.0349171 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0347125 |
| ADAR | adenosine deaminase, RNA-specific | 0.0345669 |
| NIBAN2 | niban apoptosis regulator 2 | 0.034248 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0341981 |
| YBX1 | Y box binding protein 1 | 0.0339968 |
| LDHA | lactate dehydrogenase A | 0.0335044 |
| RNF213 | ring finger protein 213 | 0.033328 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0333118 |
| SPAG9 | sperm associated antigen 9 | 0.0328624 |
| SMAD3 | SMAD family member 3 | 0.0327805 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0326025 |
| PLAU | plasminogen activator, urokinase | 0.0325505 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0318663 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0318239 |
| PRRC2C | proline-rich coiled-coil 2C | 0.031578 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0313974 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0313803 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0310188 |
| TPM4 | tropomyosin 4 | 0.0308188 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0307303 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0305894 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.029895 |
| HPCAL1 | hippocalcin-like 1 | 0.0298663 |
| PGK1 | phosphoglycerate kinase 1 | 0.0296246 |
| H1-0 | H1.0 linker histone | 0.0295976 |
| PRELID2 | PRELI domain containing 2 | 0.0295744 |
| SON | SON DNA binding protein | 0.0293645 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0288016 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0275437 |
| SET | SET nuclear proto-oncogene | 0.0273619 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0271849 |
| TPM3 | tropomyosin 3 | 0.0271574 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0271482 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.027148 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0270003 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0269728 |
| B2M | beta-2-microglobulin | 0.0268324 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0265695 |
| APP | amyloid beta (A4) precursor protein | 0.0264712 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | 0.0264642 |
| F2R | coagulation factor II (thrombin) receptor | 0.0263794 |
| MKI67 | marker of proliferation Ki-67 | 0.026306 |
| SLK | STE20-like kinase | 0.0261266 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0260066 |
| STX1A | syntaxin 1A (brain) | 0.0257707 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0256775 |
| HLA-E | major histocompatibility complex, class I, E | 0.0255045 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0254377 |
| YEATS2 | YEATS domain containing 2 | 0.0252679 |
| SQSTM1 | sequestosome 1 | 0.0250496 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0249201 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.024872 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.183887 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0938509 |
| TP63 | tumor protein p63 | -0.0938437 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0872283 |
| CD44 | CD44 molecule (Indian blood group) | -0.0833413 |
| EHBP1 | EH domain binding protein 1 | -0.0677952 |
| VIM | vimentin | -0.067661 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0670191 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0545959 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0520527 |
| HMGA1 | high mobility group AT-hook 1 | -0.0491789 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0488519 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0464714 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.045339 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0450833 |
| CADM2 | cell adhesion molecule 2 | -0.0443225 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0435571 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0424721 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0420234 |
| TNS3 | tensin 3 | -0.0412592 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0401024 |
| SRGN | serglycin | -0.0371392 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0361276 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0351994 |
| RPS23 | ribosomal protein S23 | -0.0351454 |
| RPS8 | ribosomal protein S8 | -0.0328409 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.03281 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0319917 |
| SP100 | SP100 nuclear antigen | -0.0318758 |
| EFNA5 | ephrin-A5 | -0.0306738 |
| COL5A2 | collagen, type V, alpha 2 | -0.0299053 |
| EPHA4 | EPH receptor A4 | -0.029372 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0292963 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0285212 |
| MAP4 | microtubule-associated protein 4 | -0.0284372 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0280946 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.02736 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0265078 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0253642 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0242917 |
| TMEM123 | transmembrane protein 123 | -0.0240995 |
| LRRC49 | leucine rich repeat containing 49 | -0.0240863 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0240581 |
| SBF2 | SET binding factor 2 | -0.0240537 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0238743 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.023734 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0234846 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0234842 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0233652 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0228914 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0226003 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0224604 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0217851 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0217811 |
| RPL32 | ribosomal protein L32 | -0.021768 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0216429 |
| DOCK11 | dedicator of cytokinesis 11 | -0.021461 |
| WASF2 | WAS protein family, member 2 | -0.0214468 |
| UBE3C | ubiquitin protein ligase E3C | -0.0214155 |
| RBM25 | RNA binding motif protein 25 | -0.0209766 |
| DENND1A | DENN/MADD domain containing 1A | -0.0208141 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0207939 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0207011 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0204152 |
| RPL5 | ribosomal protein L5 | -0.020385 |
| RPS29 | ribosomal protein S29 | -0.0199528 |
| CCNL1 | cyclin L1 | -0.0198936 |
| MYOF | myoferlin | -0.0196574 |
| PTK2 | protein tyrosine kinase 2 | -0.0195895 |
| NF1 | neurofibromin 1 | -0.0191635 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0191009 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0190827 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0183536 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0182966 |
| HMGB1 | high mobility group box 1 | -0.0180336 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0179739 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.017818 |
| TAPBP | TAP binding protein (tapasin) | -0.0177329 |
| RPS15 | ribosomal protein S15 | -0.0175345 |
| RPL8 | ribosomal protein L8 | -0.0174894 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0173357 |
| GNAS | GNAS complex locus | -0.0172575 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.017242 |
| RPS6 | ribosomal protein S6 | -0.0171596 |
| RGS5 | regulator of G-protein signaling 5 | -0.0170287 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0170238 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0170207 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0168822 |
| ZNF292 | zinc finger protein 292 | -0.0168545 |
| TP53 | tumor protein p53 | -0.0167853 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0167556 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0167333 |
| INTS6 | integrator complex subunit 6 | -0.0166536 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0163385 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0162596 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0162586 |
| RPL12 | ribosomal protein L12 | -0.0162459 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0161836 |
| USP34 | ubiquitin specific peptidase 34 | -0.0160994 |
| SLC39A10 | solute carrier family 39 (zinc transporter), member 10 | -0.0160166 |
