| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Riluzole hydrochloride perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Riluzole hydrochloride_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SMAD3 | SMAD family member 3 | 0.171234 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0812702 |
| NAV2 | neuron navigator 2 | 0.0753679 |
| TGM2 | transglutaminase 2 | 0.0734314 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0712594 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0707966 |
| PFKP | phosphofructokinase, platelet | 0.0663547 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0660734 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0637137 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0597652 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0580937 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0546159 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.054455 |
| VEGFA | vascular endothelial growth factor A | 0.0536205 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0524682 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.045992 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0445085 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0442427 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0435661 |
| ECE1 | endothelin converting enzyme 1 | 0.0432312 |
| PCBP2 | poly(rC) binding protein 2 | 0.0424434 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0422058 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.042194 |
| CEP250 | centrosomal protein 250kDa | 0.0416814 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0404448 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0402298 |
| CD44 | CD44 molecule (Indian blood group) | 0.0399927 |
| ANGPTL4 | angiopoietin-like 4 | 0.0394048 |
| DOCK5 | dedicator of cytokinesis 5 | 0.038142 |
| KSR1 | kinase suppressor of ras 1 | 0.0369706 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0364524 |
| SFTPA2 | surfactant protein A2 | 0.0362264 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0356211 |
| SEPTIN9 | septin 9 | 0.0356127 |
| ACTN4 | actinin, alpha 4 | 0.0353884 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0346341 |
| PLEC | plectin | 0.0334722 |
| CDCP1 | CUB domain containing protein 1 | 0.0332563 |
| NTN4 | netrin 4 | 0.0332276 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0327164 |
| KYNU | kynureninase | 0.0326823 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.032576 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0301191 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.029386 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.028924 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.028521 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0283225 |
| APP | amyloid beta (A4) precursor protein | 0.0278384 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.0275367 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0273514 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0273336 |
| MSN | moesin | 0.027045 |
| LOXL2 | lysyl oxidase-like 2 | 0.0270024 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0269841 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0268084 |
| LDHA | lactate dehydrogenase A | 0.0266174 |
| HLA-B | major histocompatibility complex, class I, B | 0.0262851 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0256842 |
| RPL3 | ribosomal protein L3 | 0.0253819 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0252399 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0244458 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0242539 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0241212 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0240962 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0239955 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0239795 |
| MLPH | melanophilin | 0.0238891 |
| TMSB4X | thymosin beta 4, X-linked | 0.0237765 |
| B2M | beta-2-microglobulin | 0.0237068 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.0236696 |
| NDRG1 | N-myc downstream regulated 1 | 0.0231634 |
| WLS | wntless Wnt ligand secretion mediator | 0.0226491 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0226304 |
| MEIS1 | Meis homeobox 1 | 0.0225269 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0224287 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0222761 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0222176 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0219986 |
| ITGAV | integrin, alpha V | 0.0216449 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0214596 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0212027 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0211777 |
| NRP1 | neuropilin 1 | 0.0211324 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0210759 |
| RAD51B | RAD51 paralog B | 0.0210285 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0209342 |
| BCL3 | B-cell CLL/lymphoma 3 | 0.0209083 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0208655 |
| RUNX2 | runt-related transcription factor 2 | 0.0207677 |
| CPNE1 | copine I | 0.0207571 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0207472 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0205486 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.020482 |
| SYNJ2 | synaptojanin 2 | 0.0204595 |
| PCDH7 | protocadherin 7 | 0.0204199 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0203972 |
| STK38L | serine/threonine kinase 38 like | 0.0203475 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.0202673 |
| YBX3 | Y box binding protein 3 | 0.020101 |
| IL6ST | interleukin 6 signal transducer | 0.020003 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.184203 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.165959 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.152907 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.127749 |
| RBM39 | RNA binding motif protein 39 | -0.103668 |
| CDH13 | cadherin 13 | -0.100642 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.097833 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0957045 |
| LOX | lysyl oxidase | -0.0940587 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0879671 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0875956 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0803492 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0771523 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0753021 |
| GPC6 | glypican 6 | -0.0751282 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0740192 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.073049 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0700749 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.065679 |
| TMSB10 | thymosin beta 10 | -0.0642295 |
| HMGA2 | high mobility group AT-hook 2 | -0.0629592 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0628023 |
| GOLGA4 | golgin A4 | -0.0613867 |
| PTMA | prothymosin, alpha | -0.0567834 |
| USP34 | ubiquitin specific peptidase 34 | -0.0567544 |
| RAI14 | retinoic acid induced 14 | -0.0557632 |
| SP100 | SP100 nuclear antigen | -0.0557401 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0551522 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0546888 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0546227 |
| CDK14 | cyclin-dependent kinase 14 | -0.0518047 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0504283 |
| MTSS1 | metastasis suppressor 1 | -0.049332 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0483798 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0468965 |
| ZNF804A | zinc finger protein 804A | -0.0463867 |
| GNAS | GNAS complex locus | -0.0451739 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0444766 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.044095 |
| DIAPH2 | diaphanous-related formin 2 | -0.0435572 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0434697 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.043184 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0425544 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0425243 |
| JMJD1C | jumonji domain containing 1C | -0.0425153 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0416272 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0415003 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.041432 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0403733 |
| TMEM263 | transmembrane protein 263 | -0.0394088 |
| IER3 | immediate early response 3 | -0.0393462 |
| DENND4A | DENN/MADD domain containing 4A | -0.0386678 |
| CFAP20DC | CFAP20 domain containing | -0.0381976 |
| VMP1 | vacuole membrane protein 1 | -0.0381383 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0380487 |
| PRELID2 | PRELI domain containing 2 | -0.0379067 |
| NLK | nemo-like kinase | -0.0378034 |
| SMAD2 | SMAD family member 2 | -0.0377031 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0370903 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0367986 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0367003 |
| AHNAK | AHNAK nucleoprotein | -0.0366695 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0363419 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0361438 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0361319 |
| MECOM | MDS1 and EVI1 complex locus | -0.0355403 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0353721 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0351197 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0348048 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0347901 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0346988 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0344188 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0342506 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0342101 |
| NUMB | numb homolog (Drosophila) | -0.0340848 |
| DMXL1 | Dmx-like 1 | -0.0335801 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0333267 |
| MAP4 | microtubule-associated protein 4 | -0.0321513 |
| RPL35A | ribosomal protein L35a | -0.0319117 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0316756 |
| TNNC1 | troponin C type 1 (slow) | -0.0314692 |
| NF1 | neurofibromin 1 | -0.0314631 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0314155 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0312613 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0311477 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0311102 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0307842 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0305935 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0304466 |
| DNER | delta/notch-like EGF repeat containing | -0.0304041 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0303163 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0301979 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0301017 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0300945 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0297051 |
| RASAL2 | RAS protein activator like 2 | -0.029678 |
| ANXA2 | annexin A2 | -0.0296618 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.0294768 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0293518 |
| CDK13 | cyclin-dependent kinase 13 | -0.0288375 |
