| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Riluzole hydrochloride perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Riluzole hydrochloride_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GRB10 | growth factor receptor-bound protein 10 | 0.172021 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.155981 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0942815 |
| LAMB3 | laminin, beta 3 | 0.0904676 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0891975 |
| KRT17 | keratin 17, type I | 0.0887593 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0846464 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0826613 |
| ATXN1 | ataxin 1 | 0.0802265 |
| SDC4 | syndecan 4 | 0.0748734 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0736595 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0721952 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0721294 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0710441 |
| PLEC | plectin | 0.0703771 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.063804 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0631742 |
| MXD1 | MAX dimerization protein 1 | 0.0609498 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0591869 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0589708 |
| HLA-A | major histocompatibility complex, class I, A | 0.0588891 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0582907 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0575023 |
| PFKP | phosphofructokinase, platelet | 0.0563147 |
| MYO5B | myosin VB | 0.0561818 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0558927 |
| KRT18 | keratin 18, type I | 0.0557022 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0550909 |
| MUC16 | mucin 16, cell surface associated | 0.0548048 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0544473 |
| LAMA4 | laminin, alpha 4 | 0.0531466 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0526919 |
| KRT7 | keratin 7, type II | 0.0522241 |
| OGA | O-GlcNAcase | 0.0522042 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0520025 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0511983 |
| RND3 | Rho family GTPase 3 | 0.0502994 |
| EZR | ezrin | 0.0501373 |
| PRDM1 | PR domain containing 1, with ZNF domain | 0.0498227 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0494559 |
| ACTG1 | actin gamma 1 | 0.0491515 |
| NDRG1 | N-myc downstream regulated 1 | 0.0482975 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0475888 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0467819 |
| VEGFA | vascular endothelial growth factor A | 0.0462895 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0460124 |
| DUSP16 | dual specificity phosphatase 16 | 0.0442341 |
| DUSP5 | dual specificity phosphatase 5 | 0.0440546 |
| KYNU | kynureninase | 0.0435682 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0435173 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0432772 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0429609 |
| DSPP | dentin sialophosphoprotein | 0.0427022 |
| MYO10 | myosin X | 0.0422122 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.042145 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0420362 |
| SET | SET nuclear proto-oncogene | 0.0419013 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0415406 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.0411693 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.0410788 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0408859 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0407564 |
| RPS3 | ribosomal protein S3 | 0.0400887 |
| CLTC | clathrin, heavy chain (Hc) | 0.0400006 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0395501 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0395197 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0393223 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0391807 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0388816 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.038879 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0379478 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.037349 |
| CYTH1 | cytohesin 1 | 0.0370139 |
| BCL2L1 | BCL2-like 1 | 0.0368275 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0367495 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0367009 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0364855 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0364639 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0364101 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0361687 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0361341 |
| MEF2D | myocyte enhancer factor 2D | 0.0360582 |
| ITGB4 | integrin, beta 4 | 0.0358279 |
| TMSB4X | thymosin beta 4, X-linked | 0.035741 |
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) | 0.0357246 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.0354958 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0352931 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 0.0349969 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0349697 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0348557 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.034845 |
| H3-3B | H3.3 histone B | 0.0348412 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0348115 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0347835 |
| SERINC5 | serine incorporator 5 | 0.0346247 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0343908 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0337689 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0337601 |
| RPLP1 | ribosomal protein, large, P1 | 0.0337343 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.0337131 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.150942 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.140035 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0963976 |
| VIM | vimentin | -0.095752 |
| GOLGA4 | golgin A4 | -0.0913443 |
| GPC6 | glypican 6 | -0.0852504 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0794613 |
| ANXA2 | annexin A2 | -0.0784127 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0764301 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0737105 |
| JMJD1C | jumonji domain containing 1C | -0.0584029 |
| RAB10 | RAB10, member RAS oncogene family | -0.0549459 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0531028 |
| PARD3 | par-3 family cell polarity regulator | -0.0509335 |
| FN1 | fibronectin 1 | -0.0502771 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.049917 |
| LAMC2 | laminin, gamma 2 | -0.0498196 |
| FMNL2 | formin-like 2 | -0.0466216 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0464516 |
| MT2A | metallothionein 2A | -0.0464378 |
| WASL | Wiskott-Aldrich syndrome-like | -0.0456695 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0447105 |
| MEF2A | myocyte enhancer factor 2A | -0.0446233 |
| KLHL24 | kelch-like family member 24 | -0.0442018 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0438788 |
| LMO7 | LIM domain 7 | -0.0436226 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0429884 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0427675 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0421776 |
| NBAS | neuroblastoma amplified sequence | -0.0420962 |
| VMP1 | vacuole membrane protein 1 | -0.0419796 |
| SRP54 | signal recognition particle 54kDa | -0.0414003 |
| ANKRD36C | ankyrin repeat domain 36C | -0.0413683 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0413431 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0409893 |
| ZNF292 | zinc finger protein 292 | -0.0403736 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0393244 |
| SGMS2 | sphingomyelin synthase 2 | -0.0392529 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0391946 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0391717 |
| FBXO11 | F-box protein 11 | -0.0391249 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0390575 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0389593 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0389134 |
| TAOK3 | TAO kinase 3 | -0.0385062 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0382454 |
| USP33 | ubiquitin specific peptidase 33 | -0.0382006 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0380964 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0378866 |
| GLG1 | golgi glycoprotein 1 | -0.0378186 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0378018 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0377812 |
| CALD1 | caldesmon 1 | -0.0377367 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0368786 |
| IGF2 | insulin-like growth factor 2 | -0.0358711 |
| SCFD1 | sec1 family domain containing 1 | -0.0358674 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0357126 |
| RBM39 | RNA binding motif protein 39 | -0.0354497 |
| QKI | QKI, KH domain containing, RNA binding | -0.0352446 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0350648 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.034914 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | -0.0348485 |
| YME1L1 | YME1-like 1 ATPase | -0.0348482 |
| SPAG9 | sperm associated antigen 9 | -0.0342959 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0342617 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0342398 |
| OLA1 | Obg-like ATPase 1 | -0.0339352 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0335782 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0334286 |
| USP3 | ubiquitin specific peptidase 3 | -0.0332854 |
| CDK13 | cyclin-dependent kinase 13 | -0.0332305 |
| CPEB3 | cytoplasmic polyadenylation element binding protein 3 | -0.0326297 |
| MYO6 | myosin VI | -0.0325471 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0325137 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.032007 |
| EGFR | epidermal growth factor receptor | -0.032004 |
| GLCCI1 | glucocorticoid induced 1 | -0.0319197 |
| RAB1A | RAB1A, member RAS oncogene family | -0.031869 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.031796 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.031419 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0311253 |
| CDC73 | cell division cycle 73 | -0.031103 |
| PAPOLA | poly(A) polymerase alpha | -0.0310737 |
| KIF13A | kinesin family member 13A | -0.0308902 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.030671 |
| GOLPH3L | golgi phosphoprotein 3-like | -0.0304893 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0304853 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0304725 |
| ZNF638 | zinc finger protein 638 | -0.0304166 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | -0.0303774 |
| MYO9B | myosin IXB | -0.0303364 |
| WDR26 | WD repeat domain 26 | -0.0302291 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0301171 |
| RESF1 | retroelement silencing factor 1 | -0.0300348 |
| STX18 | syntaxin 18 | -0.0297664 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0296539 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0295641 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 | -0.0295516 |
| HOOK3 | hook microtubule-tethering protein 3 | -0.0295148 |
| NCOA1 | nuclear receptor coactivator 1 | -0.0294311 |
