| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Riluzole hydrochloride perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Riluzole hydrochloride_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GRAMD1B | GRAM domain containing 1B | 0.259974 |
| YBX3 | Y box binding protein 3 | 0.12901 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.125748 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.101985 |
| TXNRD1 | thioredoxin reductase 1 | 0.0846691 |
| ACTG1 | actin gamma 1 | 0.0804965 |
| TPM3 | tropomyosin 3 | 0.0742754 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0734584 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0642337 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0636245 |
| ADAR | adenosine deaminase, RNA-specific | 0.0612725 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0563725 |
| VIM | vimentin | 0.0561954 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0547388 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0535785 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0531929 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0499923 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0488605 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0483385 |
| NONO | non-POU domain containing, octamer-binding | 0.0473812 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0468744 |
| TUBA1B | tubulin, alpha 1b | 0.046545 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.046323 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0456854 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0447526 |
| EXT1 | exostosin glycosyltransferase 1 | 0.044439 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0443919 |
| PFN1 | profilin 1 | 0.0437442 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0434485 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0421779 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0418452 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0412223 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.040941 |
| RRM2 | ribonucleotide reductase M2 | 0.0409071 |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 | 0.0403148 |
| SMAD3 | SMAD family member 3 | 0.0400518 |
| HLA-B | major histocompatibility complex, class I, B | 0.0395468 |
| KRT18 | keratin 18, type I | 0.0390424 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0385615 |
| CPNE1 | copine I | 0.0381017 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0376409 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0372736 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0371709 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0364924 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0361591 |
| LATS2 | large tumor suppressor kinase 2 | 0.0356006 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0354561 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0348196 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0348128 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0347682 |
| RTN4 | reticulon 4 | 0.0346984 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.034339 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0342064 |
| RPLP0 | ribosomal protein, large, P0 | 0.0335302 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0334509 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.032773 |
| SEPTIN2 | septin 2 | 0.0327009 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.031695 |
| CMIP | c-Maf inducing protein | 0.0315997 |
| YAP1 | Yes-associated protein 1 | 0.0313447 |
| TMEM41B | transmembrane protein 41B | 0.031162 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.0311102 |
| PTK2 | protein tyrosine kinase 2 | 0.0308867 |
| MSN | moesin | 0.0302739 |
| TMEM245 | transmembrane protein 245 | 0.0301709 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0301486 |
| LDHA | lactate dehydrogenase A | 0.029911 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0297665 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0292997 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0291833 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0291507 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0290207 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0290144 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0286303 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.028535 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0284957 |
| TAGLN2 | transgelin 2 | 0.0284204 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0283589 |
| IL6ST | interleukin 6 signal transducer | 0.0280241 |
| TRIM33 | tripartite motif containing 33 | 0.0277922 |
| EXOC6B | exocyst complex component 6B | 0.0277006 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0276329 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.0272675 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0272441 |
| TPI1 | triosephosphate isomerase 1 | 0.0267789 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0267294 |
| SON | SON DNA binding protein | 0.026655 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0261585 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0257674 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0257449 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0257167 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0256407 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.0254592 |
| USP36 | ubiquitin specific peptidase 36 | 0.0254533 |
| PRELID3B | PRELI domain containing 3B | 0.0249953 |
| YBX1 | Y box binding protein 1 | 0.0249577 |
| ACTN1 | actinin, alpha 1 | 0.0249045 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0246629 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0245175 |
| CDCP1 | CUB domain containing protein 1 | 0.0244625 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.121289 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.109674 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0748647 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0736282 |
| MCL1 | myeloid cell leukemia 1 | -0.0734408 |
| PRELID2 | PRELI domain containing 2 | -0.0704747 |
| RAD51B | RAD51 paralog B | -0.0701631 |
| AEBP2 | AE binding protein 2 | -0.0581632 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0560486 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0542441 |
| RYR3 | ryanodine receptor 3 | -0.0488269 |
| RSF1 | remodeling and spacing factor 1 | -0.0468117 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.046502 |
| ATXN1 | ataxin 1 | -0.0462082 |
| FMN1 | formin 1 | -0.0442792 |
| USP34 | ubiquitin specific peptidase 34 | -0.0441797 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0438584 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0435758 |
| EHBP1 | EH domain binding protein 1 | -0.0434146 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0433357 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0429838 |
| KIAA1328 | KIAA1328 | -0.0423267 |
| AHNAK | AHNAK nucleoprotein | -0.0413707 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0408891 |
| BBX | bobby sox homolog (Drosophila) | -0.0402156 |
| RBM39 | RNA binding motif protein 39 | -0.039257 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0383977 |
| HMGA2 | high mobility group AT-hook 2 | -0.0376529 |
| RYK | receptor-like tyrosine kinase | -0.0376328 |
| ZNF638 | zinc finger protein 638 | -0.0373852 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0365212 |
| MAP4 | microtubule-associated protein 4 | -0.036428 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.03608 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0356853 |
| STYK1 | serine/threonine/tyrosine kinase 1 | -0.0350278 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0339971 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0335032 |
| CDK13 | cyclin-dependent kinase 13 | -0.0334834 |
| NABP1 | nucleic acid binding protein 1 | -0.03321 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0328813 |
| EXOC4 | exocyst complex component 4 | -0.0328322 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0320687 |
| SMC4 | structural maintenance of chromosomes 4 | -0.031619 |
| INTS6 | integrator complex subunit 6 | -0.0314353 |
| EGFR | epidermal growth factor receptor | -0.0310208 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.030793 |
| CD2AP | CD2-associated protein | -0.0307268 |
| CANX | calnexin | -0.0307073 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0302995 |
| ST3GAL3 | ST3 beta-galactoside alpha-2,3-sialyltransferase 3 | -0.0297371 |
| MYSM1 | Myb-like, SWIRM and MPN domains 1 | -0.0291983 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0271139 |
| GOLGB1 | golgin B1 | -0.0269309 |
| ST7L | suppression of tumorigenicity 7 like | -0.0268846 |
| RPS6 | ribosomal protein S6 | -0.0268715 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0264671 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0263782 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0263415 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0263314 |
| NEK10 | NIMA-related kinase 10 | -0.0260345 |
| GPATCH2L | G patch domain containing 2-like | -0.0254408 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.025238 |
| DIAPH2 | diaphanous-related formin 2 | -0.0251214 |
| SNX14 | sorting nexin 14 | -0.024628 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0245962 |
| ZNF207 | zinc finger protein 207 | -0.0244719 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) | -0.0243886 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0240067 |
| WDR70 | WD repeat domain 70 | -0.0238253 |
| ZNF292 | zinc finger protein 292 | -0.023811 |
| CCDC91 | coiled-coil domain containing 91 | -0.0236525 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0236182 |
| EFNA5 | ephrin-A5 | -0.0234508 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0232259 |
| SLC25A51 | solute carrier family 25, member 51 | -0.0231674 |
| MYH15 | myosin, heavy chain 15 | -0.0230971 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0229535 |
| SMYD3 | SET and MYND domain containing 3 | -0.0229488 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0229401 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit | -0.0228429 |
| ZNF217 | zinc finger protein 217 | -0.0228143 |
| PTMA | prothymosin, alpha | -0.0228089 |
| ARMH4 | armadillo like helical domain containing 4 | -0.0227648 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0226126 |
| SEM1 | SEM1 26S proteasome subunit | -0.0225998 |
| SBF2 | SET binding factor 2 | -0.0225094 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0224785 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0218598 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0217585 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0215504 |
| H1-0 | H1.0 linker histone | -0.0214981 |
| RPL23 | ribosomal protein L23 | -0.0214509 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0214111 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0214053 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0213239 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | -0.0210637 |
| TMEM14B | transmembrane protein 14B | -0.0209808 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0208502 |
| RBM25 | RNA binding motif protein 25 | -0.020496 |
| IWS1 | IWS1 homolog (S. cerevisiae) | -0.0204179 |
