| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Riluzole hydrochloride perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Riluzole hydrochloride_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PLEC | plectin | 0.0982156 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0943977 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0841481 |
| TMSB4X | thymosin beta 4, X-linked | 0.0778622 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0777928 |
| LAMB3 | laminin, beta 3 | 0.0770304 |
| HLA-B | major histocompatibility complex, class I, B | 0.071692 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0709421 |
| KRT8 | keratin 8, type II | 0.0699689 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0676266 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0672833 |
| DSPP | dentin sialophosphoprotein | 0.0634856 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0632786 |
| MSN | moesin | 0.0619313 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0612942 |
| SDC4 | syndecan 4 | 0.0546409 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0540892 |
| VEGFA | vascular endothelial growth factor A | 0.0537665 |
| SQSTM1 | sequestosome 1 | 0.0529509 |
| LDHA | lactate dehydrogenase A | 0.051274 |
| TXNIP | thioredoxin interacting protein | 0.0492124 |
| MT2A | metallothionein 2A | 0.0490133 |
| MAP1B | microtubule-associated protein 1B | 0.0464551 |
| LAMC2 | laminin, gamma 2 | 0.0463182 |
| NONO | non-POU domain containing, octamer-binding | 0.0440439 |
| FBXO32 | F-box protein 32 | 0.0438298 |
| HLA-A | major histocompatibility complex, class I, A | 0.043454 |
| KRT18 | keratin 18, type I | 0.0431569 |
| DUSP10 | dual specificity phosphatase 10 | 0.041143 |
| CTSB | cathepsin B | 0.040476 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0391126 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0383477 |
| ACTG1 | actin gamma 1 | 0.0372927 |
| TPM3 | tropomyosin 3 | 0.0360553 |
| CALR | calreticulin | 0.0351539 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0349592 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0349284 |
| PLAU | plasminogen activator, urokinase | 0.0349229 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0344155 |
| KRT7 | keratin 7, type II | 0.0341661 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.03393 |
| MYO5B | myosin VB | 0.0335987 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0330312 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0326441 |
| DBN1 | drebrin 1 | 0.0325988 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0323437 |
| G0S2 | G0/G1 switch 2 | 0.0321215 |
| YBX3 | Y box binding protein 3 | 0.0318213 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0312649 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0298214 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0298213 |
| ARRDC3 | arrestin domain containing 3 | 0.0296991 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0296811 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0294698 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0288959 |
| LRATD2 | LRAT domain containing 2 | 0.0288332 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0285442 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0283644 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0274475 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0272309 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0267794 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0265908 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0256597 |
| PRPF38B | pre-mRNA processing factor 38B | 0.025656 |
| PGBD5 | piggyBac transposable element derived 5 | 0.0256061 |
| TJP2 | tight junction protein 2 | 0.0251405 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0249712 |
| HRNR | hornerin | 0.0248203 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0248018 |
| NDRG1 | N-myc downstream regulated 1 | 0.024707 |
| RPL3 | ribosomal protein L3 | 0.024501 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0241991 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.023222 |
| UPP1 | uridine phosphorylase 1 | 0.0229042 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0227713 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0227703 |
| OPTN | optineurin | 0.022708 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0225519 |
| OCIAD2 | OCIA domain containing 2 | 0.0225149 |
| HYOU1 | hypoxia up-regulated 1 | 0.0220774 |
| MX2 | MX dynamin-like GTPase 2 | 0.0217379 |
| RPL37 | ribosomal protein L37 | 0.0215716 |
| CFB | complement factor B | 0.0214716 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0210663 |
| MKRN1 | makorin ring finger protein 1 | 0.0209616 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0205568 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0205475 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0203859 |
| ANXA1 | annexin A1 | 0.0201483 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0198453 |
| ADAR | adenosine deaminase, RNA-specific | 0.0198361 |
| H3-3B | H3.3 histone B | 0.019502 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.019401 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.0192374 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.019129 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0189651 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0189625 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.0189475 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 | 0.018562 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0185368 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.242928 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.204761 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0986228 |
| PTMA | prothymosin, alpha | -0.0984259 |
| GOLGA4 | golgin A4 | -0.0876696 |
| ASPH | aspartate beta-hydroxylase | -0.078384 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0782682 |
| HMGA1 | high mobility group AT-hook 1 | -0.0742146 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0722983 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0676557 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0625506 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0615407 |
| CCND1 | cyclin D1 | -0.0592341 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0570657 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0555894 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0555686 |
| GNAS | GNAS complex locus | -0.0554363 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0547913 |
| POTEF | POTE ankyrin domain family, member F | -0.0527554 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0503608 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.049421 |
| ZNF292 | zinc finger protein 292 | -0.0481123 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.047971 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0478966 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0471407 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.047 |
| S100A10 | S100 calcium binding protein A10 | -0.0457203 |
| WASF2 | WAS protein family, member 2 | -0.0456354 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0456053 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0455421 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0446322 |
| RPS6 | ribosomal protein S6 | -0.044249 |
| RPS23 | ribosomal protein S23 | -0.0441849 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0440151 |
| EFNA5 | ephrin-A5 | -0.043905 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0434233 |
| FNIP1 | folliculin interacting protein 1 | -0.0429072 |
| MAP4 | microtubule-associated protein 4 | -0.0428628 |
| PAPOLA | poly(A) polymerase alpha | -0.0417457 |
| TMEM263 | transmembrane protein 263 | -0.0416747 |
| CD109 | CD109 molecule | -0.0407008 |
| CERT1 | ceramide transporter 1 | -0.0404245 |
| RPS8 | ribosomal protein S8 | -0.0398883 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0398134 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0396641 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0396383 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0396227 |
| ANXA2 | annexin A2 | -0.0396226 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0394805 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.039441 |
| ERBIN | erbb2 interacting protein | -0.03913 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0387655 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0386989 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0382959 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0380832 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0379312 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0374704 |
| INTS6 | integrator complex subunit 6 | -0.037381 |
| RPL34 | ribosomal protein L34 | -0.0373518 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0370338 |
| SPAG9 | sperm associated antigen 9 | -0.0368293 |
| UBC | ubiquitin C | -0.0366059 |
| RCOR1 | REST corepressor 1 | -0.0364176 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0362967 |
| RAB7A | RAB7A, member RAS oncogene family | -0.036219 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0358333 |
| RPL8 | ribosomal protein L8 | -0.0357041 |
| CTBP2 | C-terminal binding protein 2 | -0.0354112 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0351404 |
| PTK2 | protein tyrosine kinase 2 | -0.0349641 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0349286 |
| RBM25 | RNA binding motif protein 25 | -0.0348249 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.034593 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0343164 |
| RUNX1 | runt-related transcription factor 1 | -0.0341958 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0340868 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0334896 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.033246 |
| RLF | rearranged L-myc fusion | -0.0327897 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0327017 |
| CD2AP | CD2-associated protein | -0.0326413 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.032237 |
| FBXO11 | F-box protein 11 | -0.0320699 |
| ANLN | anillin, actin binding protein | -0.0317857 |
| USP15 | ubiquitin specific peptidase 15 | -0.0316441 |
| SETD5 | SET domain containing 5 | -0.0315498 |
| RNF145 | ring finger protein 145 | -0.031447 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0313761 |
| NAV2 | neuron navigator 2 | -0.031228 |
| NUMB | numb homolog (Drosophila) | -0.0310998 |
| HELZ | helicase with zinc finger | -0.03095 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0309203 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0308245 |
| DEK | DEK proto-oncogene | -0.030647 |
| NF1 | neurofibromin 1 | -0.0305735 |
| ARF4 | ADP-ribosylation factor 4 | -0.0304907 |
| JMJD1C | jumonji domain containing 1C | -0.0304619 |
| SEC24A | SEC24 family member A | -0.0303422 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0302489 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0301944 |
