| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Riluzole hydrochloride perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Riluzole hydrochloride_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0867922 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.086468 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0860474 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0790796 |
| NONO | non-POU domain containing, octamer-binding | 0.0762866 |
| APP | amyloid beta (A4) precursor protein | 0.0613474 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0604289 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0598615 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0554036 |
| RPL3 | ribosomal protein L3 | 0.0538268 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0511053 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0507285 |
| DOCK5 | dedicator of cytokinesis 5 | 0.049373 |
| COL5A2 | collagen, type V, alpha 2 | 0.0475949 |
| TENM2 | teneurin transmembrane protein 2 | 0.0466107 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0452796 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0448464 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.044654 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.044223 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0438139 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0422478 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0406307 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0393204 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0387005 |
| DST | dystonin | 0.0383525 |
| ENO1 | enolase 1, (alpha) | 0.0370571 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0366331 |
| PHF21A | PHD finger protein 21A | 0.035867 |
| SKIL | SKI-like proto-oncogene | 0.0346175 |
| MKI67 | marker of proliferation Ki-67 | 0.0343251 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0338835 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.0334024 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0332869 |
| GSE1 | Gse1 coiled-coil protein | 0.0324662 |
| CEP250 | centrosomal protein 250kDa | 0.0318213 |
| YAP1 | Yes-associated protein 1 | 0.0310864 |
| TMSB4X | thymosin beta 4, X-linked | 0.0309428 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0308743 |
| NHSL1 | NHS-like 1 | 0.0303111 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0301794 |
| GOLIM4 | golgi integral membrane protein 4 | 0.0300188 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0297315 |
| PHF3 | PHD finger protein 3 | 0.0295544 |
| RPL37 | ribosomal protein L37 | 0.0295164 |
| DLX2 | distal-less homeobox 2 | 0.0292856 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0284421 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0283385 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0281501 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.027743 |
| CPNE1 | copine I | 0.0274536 |
| PEG10 | paternally expressed 10 | 0.0272682 |
| HYOU1 | hypoxia up-regulated 1 | 0.0272228 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0270779 |
| DCTN1 | dynactin 1 | 0.0269063 |
| MAP7D1 | MAP7 domain containing 1 | 0.0265112 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0264519 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0262104 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0261553 |
| STAG2 | stromal antigen 2 | 0.0260636 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0259922 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0259626 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0258506 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0255657 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0253596 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0253585 |
| LDHA | lactate dehydrogenase A | 0.0251794 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0248799 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0248584 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0248355 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0248257 |
| B2M | beta-2-microglobulin | 0.0247321 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0246093 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0241131 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.0240472 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.0237627 |
| ZNF608 | zinc finger protein 608 | 0.0236988 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | 0.0236285 |
| SQSTM1 | sequestosome 1 | 0.0233158 |
| ZNF146 | zinc finger protein 146 | 0.0232425 |
| NTM | neurotrimin | 0.0231308 |
| NCOA2 | nuclear receptor coactivator 2 | 0.0230735 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0229442 |
| RIGI | RNA sensor RIG-I | 0.0224598 |
| MYO10 | myosin X | 0.0222098 |
| PPL | periplakin | 0.0220462 |
| VEGFA | vascular endothelial growth factor A | 0.0219292 |
| PLEC | plectin | 0.0218163 |
| PCDH18 | protocadherin 18 | 0.0217949 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0217777 |
| MGA | MGA, MAX dimerization protein | 0.0215435 |
| TIMELESS | timeless circadian clock | 0.0215252 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0214491 |
| PGK1 | phosphoglycerate kinase 1 | 0.021448 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0212699 |
| CMTR1 | cap methyltransferase 1 | 0.0209868 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0209296 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 0.0205782 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0205389 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0205265 |
| ZNF516 | zinc finger protein 516 | 0.0203836 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.184955 |
| CADM2 | cell adhesion molecule 2 | -0.135274 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.128652 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.109087 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0990537 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0948754 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0940115 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0900566 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0886364 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0833228 |
| MAP4 | microtubule-associated protein 4 | -0.07315 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0720349 |
| RPS8 | ribosomal protein S8 | -0.0659467 |
| SRP54 | signal recognition particle 54kDa | -0.0638302 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0627434 |
| MEIS2 | Meis homeobox 2 | -0.0571892 |
| RPS16 | ribosomal protein S16 | -0.0570742 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0562872 |
| RPS6 | ribosomal protein S6 | -0.0544845 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0543382 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0533936 |
| PFN1 | profilin 1 | -0.0531474 |
| TMSB10 | thymosin beta 10 | -0.05105 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0504909 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.05043 |
| URI1 | URI1, prefoldin-like chaperone | -0.0502185 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0484667 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0477478 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0473971 |
| LRRC4C | leucine rich repeat containing 4C | -0.0471117 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0466632 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.045968 |
| THBS1 | thrombospondin 1 | -0.0454369 |
| RTN4 | reticulon 4 | -0.045079 |
| GNAS | GNAS complex locus | -0.0450509 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0442694 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0439989 |
| TSC22D2 | TSC22 domain family, member 2 | -0.043942 |
| DEK | DEK proto-oncogene | -0.0435442 |
| PTMA | prothymosin, alpha | -0.0431012 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0425597 |
| NOP58 | NOP58 ribonucleoprotein | -0.0425566 |
| GPC3 | glypican 3 | -0.0423664 |
| RLF | rearranged L-myc fusion | -0.0416205 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0412681 |
| RPL11 | ribosomal protein L11 | -0.0409779 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0408502 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0402963 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0399933 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0399845 |
| S100A10 | S100 calcium binding protein A10 | -0.0395885 |
| POTEF | POTE ankyrin domain family, member F | -0.0391842 |
| LYST | lysosomal trafficking regulator | -0.0391224 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0389958 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.038632 |
| SRP72 | signal recognition particle 72kDa | -0.0383427 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.038079 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0379957 |
| WASF2 | WAS protein family, member 2 | -0.0377331 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0376137 |
| JMJD1C | jumonji domain containing 1C | -0.0376033 |
| TUT4 | terminal uridylyl transferase 4 | -0.037475 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0371392 |
| PLPP1 | phospholipid phosphatase 1 | -0.0369026 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0367032 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0366561 |
| RPLP1 | ribosomal protein, large, P1 | -0.0366514 |
| THOC2 | THO complex 2 | -0.036581 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0365328 |
| NEBL | nebulette | -0.0363738 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0363075 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0360411 |
| RAI1 | retinoic acid induced 1 | -0.0358101 |
| RBM25 | RNA binding motif protein 25 | -0.0356211 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0354896 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0353107 |
| EMP1 | epithelial membrane protein 1 | -0.0351932 |
| SLC44A5 | solute carrier family 44, member 5 | -0.0351611 |
| PHIP | pleckstrin homology domain interacting protein | -0.0348602 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0347809 |
| PCDH9 | protocadherin 9 | -0.0346505 |
| HMGB1 | high mobility group box 1 | -0.0343752 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0343164 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0342652 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | -0.0342438 |
| ZNF292 | zinc finger protein 292 | -0.0337139 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0331403 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0327724 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0325906 |
| HSPB1 | heat shock 27kDa protein 1 | -0.03254 |
| RPS25 | ribosomal protein S25 | -0.0325237 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0324223 |
| RPL12 | ribosomal protein L12 | -0.0321916 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.0314163 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0313609 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0313453 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0313226 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0308069 |
| FBL | fibrillarin | -0.0307701 |
| SBF2 | SET binding factor 2 | -0.0306321 |
