| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Riluzole hydrochloride perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Riluzole hydrochloride_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS16 | ribosomal protein S16 | 0.22354 |
| SMAD3 | SMAD family member 3 | 0.1334 |
| LOC112694756 | uncharaterized LOC112694756 | 0.11088 |
| SAMD4B | sterile alpha motif domain containing 4B | 0.0861473 |
| RPLP0 | ribosomal protein, large, P0 | 0.0783723 |
| VIM | vimentin | 0.0741227 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0724993 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.072167 |
| ACTG1 | actin gamma 1 | 0.0632235 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0584403 |
| MED29 | mediator complex subunit 29 | 0.05476 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0529298 |
| NONO | non-POU domain containing, octamer-binding | 0.0528026 |
| YBX1 | Y box binding protein 1 | 0.0524673 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0513435 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0508788 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0507523 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0495677 |
| SEPTIN9 | septin 9 | 0.0477508 |
| RPS3 | ribosomal protein S3 | 0.0472757 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.047024 |
| STEAP3 | STEAP family member 3, metalloreductase | 0.046039 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0442831 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0440693 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0437142 |
| RPS12 | ribosomal protein S12 | 0.0431781 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0421542 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 0.0418624 |
| ASPH | aspartate beta-hydroxylase | 0.0411403 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.040788 |
| RPL37 | ribosomal protein L37 | 0.0400565 |
| ANXA2 | annexin A2 | 0.0400033 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0396122 |
| RPL27A | ribosomal protein L27a | 0.03954 |
| RPL37A | ribosomal protein L37a | 0.0393106 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0392371 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0381761 |
| APP | amyloid beta (A4) precursor protein | 0.037699 |
| SET | SET nuclear proto-oncogene | 0.0376911 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0376172 |
| MT2A | metallothionein 2A | 0.0370863 |
| ARRDC3 | arrestin domain containing 3 | 0.0361509 |
| AFAP1 | actin filament associated protein 1 | 0.0358296 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0352788 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0352393 |
| B2M | beta-2-microglobulin | 0.0351456 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0347538 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0346844 |
| TMSB4X | thymosin beta 4, X-linked | 0.0340362 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0339875 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0329624 |
| RACK1 | receptor for activated C kinase 1 | 0.0329164 |
| RPL3 | ribosomal protein L3 | 0.0324226 |
| RPS25 | ribosomal protein S25 | 0.0324209 |
| RPL11 | ribosomal protein L11 | 0.0318323 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0315645 |
| RPL35A | ribosomal protein L35a | 0.0314905 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0313512 |
| CPNE1 | copine I | 0.0312754 |
| RPS17 | ribosomal protein S17 | 0.0312516 |
| SFTPA2 | surfactant protein A2 | 0.0310681 |
| LDHA | lactate dehydrogenase A | 0.0304739 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0301252 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0301051 |
| SQSTM1 | sequestosome 1 | 0.0298634 |
| RUNX1 | runt-related transcription factor 1 | 0.0295273 |
| PTK2 | protein tyrosine kinase 2 | 0.0288862 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0288707 |
| CACNG8 | calcium channel, voltage-dependent, gamma subunit 8 | 0.0287939 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0286067 |
| CLTA | clathrin, light chain A | 0.0279769 |
| RPL7 | ribosomal protein L7 | 0.0276289 |
| RPS8 | ribosomal protein S8 | 0.0270467 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0269741 |
| RPL30 | ribosomal protein L30 | 0.026797 |
| KRT8 | keratin 8, type II | 0.0265821 |
| ADM | adrenomedullin | 0.0264836 |
| SATB2 | SATB homeobox 2 | 0.0263861 |
| RPL26 | ribosomal protein L26 | 0.0263694 |
| ANGPTL4 | angiopoietin-like 4 | 0.0259042 |
| EXOC6B | exocyst complex component 6B | 0.0256602 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0249481 |
| CTBP2 | C-terminal binding protein 2 | 0.024907 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0248954 |
| EIF3K | eukaryotic translation initiation factor 3, subunit K | 0.0248236 |
| SMYD3 | SET and MYND domain containing 3 | 0.0246225 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0246002 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0245529 |
| FAT1 | FAT atypical cadherin 1 | 0.0245241 |
| FBXO17 | F-box protein 17 | 0.0245174 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0244774 |
| RPL36A | ribosomal protein L36a | 0.0243709 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0243437 |
| ITGAV | integrin, alpha V | 0.024294 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0241134 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.023957 |
| RPS24 | ribosomal protein S24 | 0.0239332 |
| MAP3K10 | mitogen-activated protein kinase kinase kinase 10 | 0.0239222 |
| SSH1 | slingshot protein phosphatase 1 | 0.0237394 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0235934 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AHNAK | AHNAK nucleoprotein | -0.238098 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.178883 |
| VCL | vinculin | -0.147114 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.111444 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0943648 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0764534 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0623743 |
| DST | dystonin | -0.0557655 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0536959 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0478063 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0474247 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0468518 |
| SBF2 | SET binding factor 2 | -0.046782 |
| HMGA2 | high mobility group AT-hook 2 | -0.0436264 |
| SPAG9 | sperm associated antigen 9 | -0.041339 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0412859 |
| MYOF | myoferlin | -0.0412508 |
| ZFP36 | ZFP36 ring finger protein | -0.0409789 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.039212 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0381204 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0368908 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0361669 |
| DIAPH2 | diaphanous-related formin 2 | -0.0361368 |
| ATG7 | autophagy related 7 | -0.0342072 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.033766 |
| MAP4 | microtubule-associated protein 4 | -0.0335816 |
| CDK13 | cyclin-dependent kinase 13 | -0.0335731 |
| RASAL2 | RAS protein activator like 2 | -0.033482 |
| H1-0 | H1.0 linker histone | -0.0332088 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0331758 |
| VMP1 | vacuole membrane protein 1 | -0.0324814 |
| FMNL2 | formin-like 2 | -0.032472 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0316947 |
| TMEM123 | transmembrane protein 123 | -0.0313882 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0310608 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0303923 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.0297082 |
| MCL1 | myeloid cell leukemia 1 | -0.0297053 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0293479 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0293113 |
| NHSL1 | NHS-like 1 | -0.0291991 |
| NF1 | neurofibromin 1 | -0.0289032 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0286904 |
| CARD18 | caspase recruitment domain family, member 18 | -0.0286382 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0284495 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0281475 |
| EGR1 | early growth response 1 | -0.0277628 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0276231 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0273411 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0272722 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0262505 |
| HMGA1 | high mobility group AT-hook 1 | -0.0259286 |
| ZNF407 | zinc finger protein 407 | -0.025883 |
| EGFR | epidermal growth factor receptor | -0.0257803 |
| NEK10 | NIMA-related kinase 10 | -0.0244411 |
| RBM25 | RNA binding motif protein 25 | -0.0243718 |
| CCND1 | cyclin D1 | -0.0242407 |
| SEPTIN7 | septin 7 | -0.024137 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0240298 |
| NABP1 | nucleic acid binding protein 1 | -0.0238903 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0238871 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0238537 |
| ZNF207 | zinc finger protein 207 | -0.0237294 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0234412 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0232658 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0230501 |
| EHBP1 | EH domain binding protein 1 | -0.0229795 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.022758 |
| CANX | calnexin | -0.0226177 |
| WASF2 | WAS protein family, member 2 | -0.0226172 |
| RDX | radixin | -0.0223888 |
| TPM1 | tropomyosin 1 (alpha) | -0.0223603 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0220977 |
| GOLGB1 | golgin B1 | -0.0217082 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0215774 |
| ECT2 | epithelial cell transforming 2 | -0.0213296 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0213049 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0213006 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0208199 |
| RSU1 | Ras suppressor protein 1 | -0.020818 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0207473 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0206436 |
| ARCN1 | archain 1 | -0.0205047 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0204538 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0204398 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0202423 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0201316 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0200442 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like | -0.0197467 |
| ST3GAL3 | ST3 beta-galactoside alpha-2,3-sialyltransferase 3 | -0.0196392 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -0.0196255 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0196005 |
| ZNF217 | zinc finger protein 217 | -0.0193801 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0193056 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0192128 |
| CD44 | CD44 molecule (Indian blood group) | -0.0189626 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0188613 |
| PDE10A | phosphodiesterase 10A | -0.0186113 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0181466 |
| UBE3A | ubiquitin protein ligase E3A | -0.0180524 |
