| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Riluzole hydrochloride perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Riluzole hydrochloride_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.110039 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.108613 |
| HLA-B | major histocompatibility complex, class I, B | 0.100965 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0986983 |
| B2M | beta-2-microglobulin | 0.0923504 |
| KRT18 | keratin 18, type I | 0.0884899 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0809116 |
| VEGFA | vascular endothelial growth factor A | 0.0788941 |
| KRT8 | keratin 8, type II | 0.0777563 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0775234 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0744391 |
| MT2A | metallothionein 2A | 0.0706102 |
| PLAU | plasminogen activator, urokinase | 0.0695793 |
| TGM2 | transglutaminase 2 | 0.065816 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0618754 |
| TXNIP | thioredoxin interacting protein | 0.0607376 |
| HLA-A | major histocompatibility complex, class I, A | 0.058771 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0587059 |
| TMSB10 | thymosin beta 10 | 0.0575423 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0570182 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0566935 |
| TMSB4X | thymosin beta 4, X-linked | 0.0564963 |
| LDHA | lactate dehydrogenase A | 0.0563691 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0549242 |
| PLEC | plectin | 0.0545319 |
| CALR | calreticulin | 0.0533841 |
| RPL35A | ribosomal protein L35a | 0.0511578 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0509938 |
| NONO | non-POU domain containing, octamer-binding | 0.0476221 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0475268 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0457387 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0450406 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0444044 |
| ANXA11 | annexin A11 | 0.0427665 |
| MED15 | mediator complex subunit 15 | 0.0423912 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.041581 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0414558 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0413152 |
| AFDN | afadin, adherens junction formation factor | 0.0410124 |
| RPL3 | ribosomal protein L3 | 0.0409744 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0409314 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0396626 |
| MYO5B | myosin VB | 0.0381164 |
| CPNE1 | copine I | 0.0373752 |
| SMAD3 | SMAD family member 3 | 0.0371426 |
| RPL23 | ribosomal protein L23 | 0.0368893 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0368453 |
| RPS13 | ribosomal protein S13 | 0.0364124 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0364067 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0360034 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0350818 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0346902 |
| YBX1 | Y box binding protein 1 | 0.0342393 |
| RPS19 | ribosomal protein S19 | 0.0339699 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0337957 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0336729 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0334894 |
| BRD4 | bromodomain containing 4 | 0.0327487 |
| RPL35 | ribosomal protein L35 | 0.0322891 |
| TPM3 | tropomyosin 3 | 0.0319971 |
| RPL19 | ribosomal protein L19 | 0.0318934 |
| RPL37 | ribosomal protein L37 | 0.0308209 |
| SON | SON DNA binding protein | 0.0305176 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0302456 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0301869 |
| BCL2L1 | BCL2-like 1 | 0.0301521 |
| TJP2 | tight junction protein 2 | 0.0301356 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.030131 |
| PCBP2 | poly(rC) binding protein 2 | 0.0298174 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0295416 |
| FTL | ferritin, light polypeptide | 0.0294908 |
| NIBAN2 | niban apoptosis regulator 2 | 0.029262 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0291677 |
| RPS3 | ribosomal protein S3 | 0.0291577 |
| SET | SET nuclear proto-oncogene | 0.0289381 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0286185 |
| MT1X | metallothionein 1X | 0.0285551 |
| DSPP | dentin sialophosphoprotein | 0.0283097 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0283092 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0282031 |
| FAM3C | family with sequence similarity 3, member C | 0.0279991 |
| CEP250 | centrosomal protein 250kDa | 0.0277392 |
| HLA-C | major histocompatibility complex, class I, C | 0.0276548 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0274954 |
| LAMC2 | laminin, gamma 2 | 0.0272617 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0272318 |
| MSN | moesin | 0.0271302 |
| KRT7 | keratin 7, type II | 0.0270691 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0269866 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0269203 |
| OPTN | optineurin | 0.0267754 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0267081 |
| JUN | jun proto-oncogene | 0.0265696 |
| ACTN1 | actinin, alpha 1 | 0.0265615 |
| KLC1 | kinesin light chain 1 | 0.026448 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0264415 |
| ARRDC3 | arrestin domain containing 3 | 0.0261732 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.026025 |
| PNN | pinin, desmosome associated protein | 0.0259723 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0259543 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.117804 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.11049 |
| FN1 | fibronectin 1 | -0.102199 |
| INTS6 | integrator complex subunit 6 | -0.0970511 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0954014 |
| LMO7 | LIM domain 7 | -0.0945494 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0897482 |
| ANXA2 | annexin A2 | -0.0796138 |
| HMGA1 | high mobility group AT-hook 1 | -0.0767349 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0761643 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0620963 |
| CD2AP | CD2-associated protein | -0.0598978 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0566697 |
| AHNAK | AHNAK nucleoprotein | -0.0560745 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0546251 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0540675 |
| EMP1 | epithelial membrane protein 1 | -0.0535413 |
| CD44 | CD44 molecule (Indian blood group) | -0.0526284 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0517861 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0516608 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0510251 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0508806 |
| GNAS | GNAS complex locus | -0.0506886 |
| SYT14 | synaptotagmin XIV | -0.0484951 |
| ERBIN | erbb2 interacting protein | -0.0473879 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0471245 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.046881 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0468481 |
| PLSCR1 | phospholipid scramblase 1 | -0.0462498 |
| TMEM123 | transmembrane protein 123 | -0.0453564 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0423955 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0423008 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0421436 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0409788 |
| RCOR1 | REST corepressor 1 | -0.0405636 |
| VCL | vinculin | -0.0398204 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0397347 |
| MEF2A | myocyte enhancer factor 2A | -0.0396722 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0396369 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0391228 |
| RUNX1 | runt-related transcription factor 1 | -0.0383621 |
| CDK13 | cyclin-dependent kinase 13 | -0.0376222 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0367643 |
| MYO6 | myosin VI | -0.0366654 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0366219 |
| ASPH | aspartate beta-hydroxylase | -0.0363864 |
| HMGA2 | high mobility group AT-hook 2 | -0.0361801 |
| DAPK1 | death-associated protein kinase 1 | -0.0360492 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0354765 |
| GOLGB1 | golgin B1 | -0.0352319 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0351584 |
| SP100 | SP100 nuclear antigen | -0.0349451 |
| SULF2 | sulfatase 2 | -0.0347346 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0346951 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0343155 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.034046 |
| DSG2 | desmoglein 2 | -0.0340036 |
| SQSTM1 | sequestosome 1 | -0.0339103 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0337346 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0336265 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0324779 |
| LRRC23 | leucine rich repeat containing 23 | -0.0324406 |
| TPM4 | tropomyosin 4 | -0.0316268 |
| MUC20 | mucin 20, cell surface associated | -0.031551 |
| PHF3 | PHD finger protein 3 | -0.0314228 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0312909 |
| EXOC4 | exocyst complex component 4 | -0.0312711 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0312028 |
| USP34 | ubiquitin specific peptidase 34 | -0.0308348 |
| HLA-E | major histocompatibility complex, class I, E | -0.0303487 |
| CLDN1 | claudin 1 | -0.0303286 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0303023 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0300317 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.029978 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0296735 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0294547 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0292091 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0291768 |
| RSF1 | remodeling and spacing factor 1 | -0.028438 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0283893 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0283407 |
| JMJD1C | jumonji domain containing 1C | -0.0283126 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0282134 |
| KYNU | kynureninase | -0.0281083 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0279824 |
| CCND1 | cyclin D1 | -0.0278378 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0277985 |
| ACTG1 | actin gamma 1 | -0.0277806 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0274597 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0272219 |
| RPS15 | ribosomal protein S15 | -0.0271185 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0270747 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0270187 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0267201 |
| NF1 | neurofibromin 1 | -0.0266872 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0265294 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0263872 |
| HDAC9 | histone deacetylase 9 | -0.0263666 |
| ZNF638 | zinc finger protein 638 | -0.0257799 |
| ANKRD10 | ankyrin repeat domain 10 | -0.025686 |
