| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Riluzole hydrochloride perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Riluzole hydrochloride_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.145732 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.140196 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0809264 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0784813 |
| MT2A | metallothionein 2A | 0.0722779 |
| RPL3 | ribosomal protein L3 | 0.0676375 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0529825 |
| HRNR | hornerin | 0.0498403 |
| FOSL1 | FOS-like antigen 1 | 0.0441723 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0431813 |
| GLRX | glutaredoxin (thioltransferase) | 0.0429332 |
| FTL | ferritin, light polypeptide | 0.0426246 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0417963 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.038585 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0378208 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0376198 |
| SGMS2 | sphingomyelin synthase 2 | 0.0359128 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.035779 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0350651 |
| CAPRIN2 | caprin family member 2 | 0.0340811 |
| SMTN | smoothelin | 0.033674 |
| NONO | non-POU domain containing, octamer-binding | 0.033048 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0324292 |
| CD68 | CD68 molecule | 0.0319197 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0314248 |
| CEP250 | centrosomal protein 250kDa | 0.0310542 |
| PRELID3B | PRELI domain containing 3B | 0.0304574 |
| YBX3 | Y box binding protein 3 | 0.0298677 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 | 0.0289581 |
| DST | dystonin | 0.0275598 |
| RPS4X | ribosomal protein S4, X-linked | 0.0272233 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0269742 |
| MCL1 | myeloid cell leukemia 1 | 0.0265268 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0260799 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0258169 |
| ANK2 | ankyrin 2, neuronal | 0.0256912 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0256764 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.025273 |
| G0S2 | G0/G1 switch 2 | 0.0252681 |
| RPL9 | ribosomal protein L9 | 0.0252651 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0244731 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0244622 |
| CPNE1 | copine I | 0.0242458 |
| LDHA | lactate dehydrogenase A | 0.0239956 |
| RPL37 | ribosomal protein L37 | 0.0239298 |
| ACTG1 | actin gamma 1 | 0.0239061 |
| TMEM156 | transmembrane protein 156 | 0.0220189 |
| DBN1 | drebrin 1 | 0.0219558 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0216192 |
| SET | SET nuclear proto-oncogene | 0.0214527 |
| FLNB | filamin B, beta | 0.0213051 |
| AXL | AXL receptor tyrosine kinase | 0.02108 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0210636 |
| PLAUR | plasminogen activator, urokinase receptor | 0.02094 |
| ADTRP | androgen-dependent TFPI-regulating protein | 0.0208735 |
| ASPH | aspartate beta-hydroxylase | 0.0207344 |
| HLA-C | major histocompatibility complex, class I, C | 0.020462 |
| DGKI | diacylglycerol kinase, iota | 0.019909 |
| GSE1 | Gse1 coiled-coil protein | 0.0198652 |
| UPP1 | uridine phosphorylase 1 | 0.0197749 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase | 0.0196645 |
| RAD51B | RAD51 paralog B | 0.0193057 |
| MINK1 | misshapen-like kinase 1 | 0.0190166 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0189772 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0186967 |
| YBX1 | Y box binding protein 1 | 0.0185181 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0181229 |
| RASA2 | RAS p21 protein activator 2 | 0.0179518 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0176481 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0176401 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0174533 |
| NUP188 | nucleoporin 188kDa | 0.0174294 |
| DIDO1 | death inducer-obliterator 1 | 0.0173857 |
| OCIAD2 | OCIA domain containing 2 | 0.0172702 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0169831 |
| SON | SON DNA binding protein | 0.016846 |
| CAMSAP1 | calmodulin regulated spectrin-associated protein 1 | 0.0168162 |
| RACK1 | receptor for activated C kinase 1 | 0.0167987 |
| ANGPTL4 | angiopoietin-like 4 | 0.0167671 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0166622 |
| RPLP0 | ribosomal protein, large, P0 | 0.0162879 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0162874 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0162135 |
| RPS17 | ribosomal protein S17 | 0.0161779 |
| CTTNBP2NL | CTTNBP2 N-terminal like | 0.016111 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0160011 |
| RPL11 | ribosomal protein L11 | 0.0159919 |
| RPL15 | ribosomal protein L15 | 0.0159001 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0156363 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0155925 |
| NOP14 | NOP14 nucleolar protein | 0.0155911 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0154362 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0153103 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0152136 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0147666 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | 0.0147616 |
| SH3BP5L | SH3-binding domain protein 5-like | 0.0147454 |
| TCOF1 | Treacher Collins-Franceschetti syndrome 1 | 0.0147391 |
| DDX23 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 | 0.0147073 |
| UCHL3 | ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) | 0.0147039 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DLC1 | DLC1 Rho GTPase activating protein | -0.206038 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.159354 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.119744 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.119395 |
| NAV3 | neuron navigator 3 | -0.104223 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0915247 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0905797 |
| HDAC9 | histone deacetylase 9 | -0.0824554 |
| FRMD6 | FERM domain containing 6 | -0.0760315 |
| ZNF438 | zinc finger protein 438 | -0.0734026 |
| NABP1 | nucleic acid binding protein 1 | -0.067211 |
| HMGA2 | high mobility group AT-hook 2 | -0.065189 |
| AHNAK | AHNAK nucleoprotein | -0.0638911 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0603748 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0573689 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0568735 |
| PARD3 | par-3 family cell polarity regulator | -0.0550894 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.054725 |
| TTR | transthyretin | -0.0543439 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0535205 |
| LAMB3 | laminin, beta 3 | -0.0527467 |
| DIAPH3 | diaphanous-related formin 3 | -0.0518909 |
| RUNX1 | runt-related transcription factor 1 | -0.0513833 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.050103 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0496781 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0496726 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0494911 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0491339 |
| RPL8 | ribosomal protein L8 | -0.0453988 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.045205 |
| RPS6 | ribosomal protein S6 | -0.0451367 |
| FRMD4A | FERM domain containing 4A | -0.044799 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0442125 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0441243 |
| GNAS | GNAS complex locus | -0.0439467 |
| CANX | calnexin | -0.0438194 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0432273 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0421797 |
| MKI67 | marker of proliferation Ki-67 | -0.0419685 |
| ERBIN | erbb2 interacting protein | -0.0418968 |
| PGK1 | phosphoglycerate kinase 1 | -0.0418015 |
| NF1 | neurofibromin 1 | -0.0415002 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0411167 |
| SETD5 | SET domain containing 5 | -0.040254 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0401661 |
| SP100 | SP100 nuclear antigen | -0.0401034 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0400873 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0398467 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0395851 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0391068 |
| RPS8 | ribosomal protein S8 | -0.0390169 |
| SBF2 | SET binding factor 2 | -0.0389834 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0388321 |
| PTK2 | protein tyrosine kinase 2 | -0.0384247 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0371353 |
| FMNL2 | formin-like 2 | -0.0364499 |
| MATR3 | matrin 3 | -0.0357009 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.0351091 |
| GPHN | gephyrin | -0.0346664 |
| RPLP1 | ribosomal protein, large, P1 | -0.0344148 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0343706 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0342192 |
| TPM4 | tropomyosin 4 | -0.0337434 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0334578 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.033417 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0333108 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0331277 |
| RPL34 | ribosomal protein L34 | -0.0327377 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.032732 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0320284 |
| RPS20 | ribosomal protein S20 | -0.0314195 |
| ZNF207 | zinc finger protein 207 | -0.0314043 |
| ZNF292 | zinc finger protein 292 | -0.0313403 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0311752 |
| MTDH | metadherin | -0.0311059 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.030608 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0305586 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0303122 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0302948 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0302583 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0300531 |
| MAP4 | microtubule-associated protein 4 | -0.0300273 |
| HMGA1 | high mobility group AT-hook 1 | -0.0299709 |
| RPL14 | ribosomal protein L14 | -0.0299555 |
| RBM25 | RNA binding motif protein 25 | -0.0298312 |
| INTS6 | integrator complex subunit 6 | -0.0297966 |
| USP34 | ubiquitin specific peptidase 34 | -0.029779 |
| COG5 | component of oligomeric golgi complex 5 | -0.0297691 |
| SNX14 | sorting nexin 14 | -0.0293759 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0292725 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0291401 |
| PAPOLA | poly(A) polymerase alpha | -0.0287289 |
| MTAP | methylthioadenosine phosphorylase | -0.0287015 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0286721 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.028582 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0284909 |
| NSD3 | nuclear receptor binding SET domain protein 3 | -0.0284678 |
| RPL32 | ribosomal protein L32 | -0.0284121 |
| GOLGA4 | golgin A4 | -0.0283805 |
| PTMA | prothymosin, alpha | -0.0283789 |
