| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Riluzole hydrochloride perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Riluzole hydrochloride_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HLA-B | major histocompatibility complex, class I, B | 0.184038 |
| B2M | beta-2-microglobulin | 0.167077 |
| VEGFA | vascular endothelial growth factor A | 0.151601 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.141299 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.131155 |
| STC1 | stanniocalcin 1 | 0.10667 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0923414 |
| SMAD3 | SMAD family member 3 | 0.087423 |
| HLA-C | major histocompatibility complex, class I, C | 0.0845628 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0809188 |
| COL5A1 | collagen, type V, alpha 1 | 0.0762206 |
| ANGPTL4 | angiopoietin-like 4 | 0.0752604 |
| MT2A | metallothionein 2A | 0.0740548 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0723613 |
| PLEC | plectin | 0.0707297 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0705744 |
| HLA-A | major histocompatibility complex, class I, A | 0.067442 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0663457 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0646113 |
| CEP250 | centrosomal protein 250kDa | 0.0570483 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0568403 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0558001 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.054248 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0535538 |
| TMSB10 | thymosin beta 10 | 0.05328 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0529941 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0512828 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0490262 |
| MSN | moesin | 0.0477492 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0477489 |
| MLPH | melanophilin | 0.047459 |
| LOXL2 | lysyl oxidase-like 2 | 0.0472966 |
| NONO | non-POU domain containing, octamer-binding | 0.0471697 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0467408 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0437152 |
| TGM2 | transglutaminase 2 | 0.0432012 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0425057 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0418935 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0416407 |
| SVIL | supervillin | 0.0396101 |
| FAM20C | family with sequence similarity 20, member C | 0.0395895 |
| TMEM178B | transmembrane protein 178B | 0.0391334 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0386869 |
| DNAAF9 | dynein axonemal assembly factor 9 | 0.038441 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0377165 |
| CALR | calreticulin | 0.0374478 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0372288 |
| AFAP1 | actin filament associated protein 1 | 0.0360164 |
| APP | amyloid beta (A4) precursor protein | 0.0355207 |
| SON | SON DNA binding protein | 0.035386 |
| PGK1 | phosphoglycerate kinase 1 | 0.0352987 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0343654 |
| FAT1 | FAT atypical cadherin 1 | 0.0337311 |
| SFTPA2 | surfactant protein A2 | 0.0324906 |
| RPL3 | ribosomal protein L3 | 0.0323477 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.031789 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.031775 |
| HLA-E | major histocompatibility complex, class I, E | 0.0315666 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0311934 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0306856 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0305288 |
| NAV1 | neuron navigator 1 | 0.0302699 |
| OPTN | optineurin | 0.0299903 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0299328 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0296255 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0296154 |
| MX1 | MX dynamin-like GTPase 1 | 0.0293712 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | 0.0291824 |
| TPM3 | tropomyosin 3 | 0.0289503 |
| CPNE1 | copine I | 0.0283446 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.02806 |
| HDAC9 | histone deacetylase 9 | 0.0280108 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0279781 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0277428 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0274687 |
| ADAR | adenosine deaminase, RNA-specific | 0.0273409 |
| AFDN | afadin, adherens junction formation factor | 0.0273364 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0272803 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0270234 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0269441 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0268212 |
| FLNB | filamin B, beta | 0.0267549 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0267452 |
| ARRDC3 | arrestin domain containing 3 | 0.0265766 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0260064 |
| BSG | basigin (Ok blood group) | 0.0259165 |
| SDC4 | syndecan 4 | 0.0258203 |
| PFKP | phosphofructokinase, platelet | 0.0254739 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0254529 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0251074 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0248871 |
| ACTN4 | actinin, alpha 4 | 0.0247692 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.024649 |
| ANXA2 | annexin A2 | 0.0246193 |
| RNF213 | ring finger protein 213 | 0.0245192 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0240977 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0240911 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0240595 |
| SEPTIN2 | septin 2 | 0.0239445 |
| CLIC4 | chloride intracellular channel 4 | 0.0236713 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.238994 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.182626 |
| FN1 | fibronectin 1 | -0.17079 |
| COL1A1 | collagen, type I, alpha 1 | -0.154954 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0868199 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0843055 |
| CDH13 | cadherin 13 | -0.0737799 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0626286 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0604672 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0534402 |
| TPM4 | tropomyosin 4 | -0.0478587 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0476595 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.044799 |
| PTMA | prothymosin, alpha | -0.0440774 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0432664 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0411383 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0397662 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0379129 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0374912 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0371229 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0368017 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0367438 |
| CD44 | CD44 molecule (Indian blood group) | -0.0363428 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0360221 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0359356 |
| POTEF | POTE ankyrin domain family, member F | -0.0358578 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0357843 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0356793 |
| VCAN | versican | -0.0354616 |
| IER3 | immediate early response 3 | -0.0353539 |
| VCL | vinculin | -0.0351779 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0349819 |
| INTS6 | integrator complex subunit 6 | -0.0339722 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0338433 |
| FBXO11 | F-box protein 11 | -0.0336178 |
| ZNF292 | zinc finger protein 292 | -0.0333971 |
| LPCAT2 | lysophosphatidylcholine acyltransferase 2 | -0.0328848 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0323371 |
| MAP4 | microtubule-associated protein 4 | -0.032215 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0317996 |
| IL1B | interleukin 1, beta | -0.0317079 |
| CDK13 | cyclin-dependent kinase 13 | -0.0312569 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.030689 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0303318 |
| ANKRD28 | ankyrin repeat domain 28 | -0.030276 |
| INHBA | inhibin, beta A | -0.0297288 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0296371 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.029486 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0292322 |
| RPS8 | ribosomal protein S8 | -0.0290269 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0288382 |
| CENPF | centromere protein F, 350/400kDa | -0.0284293 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0283113 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0282763 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0276582 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0274191 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0271418 |
| JMJD1C | jumonji domain containing 1C | -0.0268539 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0268339 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0266861 |
| COLEC10 | collectin sub-family member 10 (C-type lectin) | -0.0266652 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0264636 |
| ITGA1 | integrin, alpha 1 | -0.0263239 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.0259106 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0258749 |
| HMGA1 | high mobility group AT-hook 1 | -0.0256035 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0254502 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0253453 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0252416 |
| DSTN | destrin (actin depolymerizing factor) | -0.0251896 |
| LOX | lysyl oxidase | -0.0251727 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.025025 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0248814 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0248072 |
| GOLGA4 | golgin A4 | -0.0245463 |
| SETD5 | SET domain containing 5 | -0.0244443 |
| KYNU | kynureninase | -0.0243825 |
| SNX14 | sorting nexin 14 | -0.0243665 |
| TMEM263 | transmembrane protein 263 | -0.024251 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0241333 |
| NABP1 | nucleic acid binding protein 1 | -0.0240922 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.023887 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0238598 |
| COL5A2 | collagen, type V, alpha 2 | -0.0237994 |
| PKM | pyruvate kinase, muscle | -0.0237263 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0233821 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0231329 |
| VMP1 | vacuole membrane protein 1 | -0.0228785 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0228729 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0226952 |
| RSF1 | remodeling and spacing factor 1 | -0.0226328 |
| FRMD4A | FERM domain containing 4A | -0.0225828 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0224423 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0223958 |
| SEC24A | SEC24 family member A | -0.0221062 |
| TWIST2 | twist family bHLH transcription factor 2 | -0.0219446 |
| THBS1 | thrombospondin 1 | -0.0217864 |
| RTN4 | reticulon 4 | -0.021715 |
| RPS25 | ribosomal protein S25 | -0.0216504 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0216177 |
