| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Riluzole hydrochloride perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Riluzole hydrochloride_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.223383 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.216377 |
| LDHA | lactate dehydrogenase A | 0.126401 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.125815 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.119951 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.108219 |
| MSN | moesin | 0.105327 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.104565 |
| LOC112694756 | uncharaterized LOC112694756 | 0.097238 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0925624 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0918363 |
| NONO | non-POU domain containing, octamer-binding | 0.0882379 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.082664 |
| CALR | calreticulin | 0.081937 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0781764 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0758927 |
| TMSB10 | thymosin beta 10 | 0.0732421 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0689122 |
| HDAC9 | histone deacetylase 9 | 0.0671389 |
| NDRG1 | N-myc downstream regulated 1 | 0.0656927 |
| CEP250 | centrosomal protein 250kDa | 0.0646197 |
| B2M | beta-2-microglobulin | 0.0624552 |
| FTL | ferritin, light polypeptide | 0.059971 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0584318 |
| VEGFA | vascular endothelial growth factor A | 0.0545453 |
| PGK1 | phosphoglycerate kinase 1 | 0.0541612 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0514291 |
| HLA-B | major histocompatibility complex, class I, B | 0.0510378 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0507754 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0506599 |
| ADM | adrenomedullin | 0.0502745 |
| MT2A | metallothionein 2A | 0.0496468 |
| FLNA | filamin A, alpha | 0.0491546 |
| JUN | jun proto-oncogene | 0.0490999 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0487828 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0475335 |
| SMAD3 | SMAD family member 3 | 0.0474548 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0463767 |
| HLA-A | major histocompatibility complex, class I, A | 0.0460633 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0446162 |
| RUNX1 | runt-related transcription factor 1 | 0.0443938 |
| CD44 | CD44 molecule (Indian blood group) | 0.0437911 |
| SYNJ2 | synaptojanin 2 | 0.0427173 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0404398 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0403261 |
| TENM2 | teneurin transmembrane protein 2 | 0.0391566 |
| SERINC3 | serine incorporator 3 | 0.0377117 |
| EGR1 | early growth response 1 | 0.037347 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0373384 |
| ENO1 | enolase 1, (alpha) | 0.0372619 |
| FMNL2 | formin-like 2 | 0.0371117 |
| STC1 | stanniocalcin 1 | 0.0365245 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0357538 |
| GLIS3 | GLIS family zinc finger 3 | 0.0356947 |
| FLNB | filamin B, beta | 0.035626 |
| NCOR2 | nuclear receptor corepressor 2 | 0.035419 |
| SFTPA2 | surfactant protein A2 | 0.0353053 |
| RPL3 | ribosomal protein L3 | 0.0347586 |
| MLPH | melanophilin | 0.034494 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0334242 |
| NAV1 | neuron navigator 1 | 0.0327152 |
| ANXA2 | annexin A2 | 0.0326102 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.032383 |
| SFXN3 | sideroflexin 3 | 0.0322006 |
| OPTN | optineurin | 0.032048 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0318693 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0307595 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0305968 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0303514 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0299399 |
| TAGLN2 | transgelin 2 | 0.0286232 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0286189 |
| RPL11 | ribosomal protein L11 | 0.0284385 |
| MYO10 | myosin X | 0.0283677 |
| MYOF | myoferlin | 0.0283437 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.028214 |
| SFRP1 | secreted frizzled-related protein 1 | 0.0278777 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0275888 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0274857 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0274029 |
| SET | SET nuclear proto-oncogene | 0.0273748 |
| MT1X | metallothionein 1X | 0.0268105 |
| PFN1 | profilin 1 | 0.0266311 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.0265479 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0263817 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0260048 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0259575 |
| FRMD4A | FERM domain containing 4A | 0.0257354 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.025711 |
| ACTN1 | actinin, alpha 1 | 0.025343 |
| COL5A1 | collagen, type V, alpha 1 | 0.0252667 |
| FOSL1 | FOS-like antigen 1 | 0.0251619 |
| ASPH | aspartate beta-hydroxylase | 0.0248404 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0247299 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0245098 |
| RLIM | ring finger protein, LIM domain interacting | 0.0238819 |
| CPNE1 | copine I | 0.0236966 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0236153 |
| HLA-C | major histocompatibility complex, class I, C | 0.0233078 |
| MCL1 | myeloid cell leukemia 1 | 0.0232862 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | -0.196747 |
| FN1 | fibronectin 1 | -0.15097 |
| VCL | vinculin | -0.0995384 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0905754 |
| BICC1 | BicC family RNA binding protein 1 | -0.0761049 |
| VCAN | versican | -0.0686283 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0595103 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0516586 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0507524 |
| KYNU | kynureninase | -0.0501351 |
| INTS6 | integrator complex subunit 6 | -0.0498428 |
| RAI14 | retinoic acid induced 14 | -0.0491025 |
| AHNAK | AHNAK nucleoprotein | -0.04697 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0441418 |
| FBXO32 | F-box protein 32 | -0.0432909 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0417799 |
| QKI | QKI, KH domain containing, RNA binding | -0.0393862 |
| EHBP1 | EH domain binding protein 1 | -0.037609 |
| GNAS | GNAS complex locus | -0.0372786 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0370104 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.036474 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0362567 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0353973 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0349676 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0347546 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.034722 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0342486 |
| GOLGA4 | golgin A4 | -0.0340802 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0340459 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0336554 |
| MAP4 | microtubule-associated protein 4 | -0.0333162 |
| NABP1 | nucleic acid binding protein 1 | -0.0328308 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0327945 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0324362 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0321585 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0319773 |
| MMP12 | matrix metallopeptidase 12 | -0.0316498 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0316218 |
| DIAPH2 | diaphanous-related formin 2 | -0.0313536 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.03114 |
| TKT | transketolase | -0.0310905 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.031039 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0308891 |
| IER3 | immediate early response 3 | -0.0307717 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0307636 |
| PHF3 | PHD finger protein 3 | -0.0307075 |
| TNS3 | tensin 3 | -0.0300789 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0297267 |
| CDK13 | cyclin-dependent kinase 13 | -0.0296016 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0279886 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0279884 |
| VIM | vimentin | -0.02762 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0273913 |
| TLE4 | transducin-like enhancer of split 4 | -0.0272007 |
| RIGI | RNA sensor RIG-I | -0.0269546 |
| CD2AP | CD2-associated protein | -0.0267016 |
| RPS6 | ribosomal protein S6 | -0.0266461 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0264056 |
| AHI1 | Abelson helper integration site 1 | -0.0263232 |
| PLSCR1 | phospholipid scramblase 1 | -0.0262961 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0261786 |
| STK17A | serine/threonine kinase 17a | -0.0260716 |
| RND3 | Rho family GTPase 3 | -0.0257822 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0257588 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.025712 |
| RPL23 | ribosomal protein L23 | -0.0256881 |
| TAPBP | TAP binding protein (tapasin) | -0.0256737 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0255895 |
| PALLD | palladin, cytoskeletal associated protein | -0.025535 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0250217 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0249781 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0248198 |
| DCBLD1 | discoidin, CUB and LCCL domain containing 1 | -0.0246427 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0243688 |
| SBF2 | SET binding factor 2 | -0.0243295 |
| SCARB1 | scavenger receptor class B, member 1 | -0.0242907 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0242893 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.024144 |
| SQSTM1 | sequestosome 1 | -0.024095 |
| LRRC7 | leucine rich repeat containing 7 | -0.0240443 |
| OSMR | oncostatin M receptor | -0.0239449 |
| KLHL24 | kelch-like family member 24 | -0.0237968 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0237707 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0235482 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0231631 |
| USP34 | ubiquitin specific peptidase 34 | -0.0231513 |
| SRGN | serglycin | -0.0231459 |
| FNIP1 | folliculin interacting protein 1 | -0.0230536 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0226339 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0226131 |
| COL4A1 | collagen, type IV, alpha 1 | -0.0223387 |
| DEK | DEK proto-oncogene | -0.0222178 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0220535 |
| WDR45B | WD repeat domain 45B | -0.0219886 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0218842 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0218311 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0216948 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0216622 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0216249 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0215145 |
