| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Riluzole hydrochloride perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Riluzole hydrochloride_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.323298 |
| COL6A3 | collagen, type VI, alpha 3 | 0.23254 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.193501 |
| HLA-B | major histocompatibility complex, class I, B | 0.100441 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0959388 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0928359 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.072648 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0699522 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0694213 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0688425 |
| COL5A1 | collagen, type V, alpha 1 | 0.054933 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0541349 |
| VEGFA | vascular endothelial growth factor A | 0.05342 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.053022 |
| BSG | basigin (Ok blood group) | 0.052501 |
| CD44 | CD44 molecule (Indian blood group) | 0.051619 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.0509475 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0501514 |
| HLA-C | major histocompatibility complex, class I, C | 0.0497824 |
| PRELID2 | PRELI domain containing 2 | 0.0494185 |
| FAM13A | family with sequence similarity 13, member A | 0.048379 |
| HLA-A | major histocompatibility complex, class I, A | 0.0482876 |
| APP | amyloid beta (A4) precursor protein | 0.0476697 |
| RRM2 | ribonucleotide reductase M2 | 0.0459207 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0456204 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0446033 |
| HMGA2 | high mobility group AT-hook 2 | 0.0437881 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0436872 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0421698 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0412095 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.041035 |
| SMYD3 | SET and MYND domain containing 3 | 0.0395922 |
| EXOC4 | exocyst complex component 4 | 0.0388316 |
| MT2A | metallothionein 2A | 0.0387837 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0385084 |
| ACTG1 | actin gamma 1 | 0.0384993 |
| FLNA | filamin A, alpha | 0.0384054 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0382777 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.038269 |
| LOXL2 | lysyl oxidase-like 2 | 0.0374727 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0373131 |
| CALD1 | caldesmon 1 | 0.0362599 |
| ATXN1 | ataxin 1 | 0.0359734 |
| ALK | anaplastic lymphoma receptor tyrosine kinase | 0.0354487 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0353588 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0345222 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0335814 |
| NONO | non-POU domain containing, octamer-binding | 0.033324 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0332001 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0330399 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0328423 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0328114 |
| STC1 | stanniocalcin 1 | 0.0324976 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0318266 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0306755 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0305746 |
| EGFR | epidermal growth factor receptor | 0.0299909 |
| GSE1 | Gse1 coiled-coil protein | 0.0294366 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0293909 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0293571 |
| SON | SON DNA binding protein | 0.0292692 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.028869 |
| THBS1 | thrombospondin 1 | 0.0285567 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0276226 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0275402 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.027476 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0274412 |
| USP47 | ubiquitin specific peptidase 47 | 0.0273842 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0272403 |
| SDC2 | syndecan 2 | 0.026962 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0268608 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0267497 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0267286 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0266547 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0266519 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0262889 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0262665 |
| FLOT1 | flotillin 1 | 0.0261491 |
| MSN | moesin | 0.0257874 |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 | 0.0256302 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0254704 |
| RPL36A | ribosomal protein L36a | 0.0254567 |
| IGF2 | insulin-like growth factor 2 | 0.0253951 |
| HYOU1 | hypoxia up-regulated 1 | 0.0251527 |
| MYO9B | myosin IXB | 0.02514 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0248507 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0247947 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0246923 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0244528 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0244214 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0243985 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0243391 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0242871 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0242853 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0239694 |
| RNF213 | ring finger protein 213 | 0.0237804 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0234978 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0233855 |
| YBX1 | Y box binding protein 1 | 0.0232895 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0230305 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.233852 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.123469 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0707116 |
| PRSS23 | protease, serine, 23 | -0.0680518 |
| GOLGA4 | golgin A4 | -0.0640064 |
| COL1A1 | collagen, type I, alpha 1 | -0.0600612 |
| COL1A2 | collagen, type I, alpha 2 | -0.0588621 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0558835 |
| LOX | lysyl oxidase | -0.0527367 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0518125 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0512489 |
| MAP1B | microtubule-associated protein 1B | -0.0508834 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0493683 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0466763 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0457043 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0450347 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0448412 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0445014 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0442347 |
| FMNL2 | formin-like 2 | -0.043933 |
| CLINT1 | clathrin interactor 1 | -0.0428601 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0416277 |
| EFNA5 | ephrin-A5 | -0.0394326 |
| COL5A2 | collagen, type V, alpha 2 | -0.0384268 |
| NAV2 | neuron navigator 2 | -0.0381054 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0376981 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0372942 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0367573 |
| AHNAK | AHNAK nucleoprotein | -0.0367187 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0361726 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0360138 |
| CD99 | CD99 molecule | -0.035863 |
| PTMA | prothymosin, alpha | -0.0357923 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0350712 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0340026 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0339743 |
| TMEM165 | transmembrane protein 165 | -0.0334394 |
| FTL | ferritin, light polypeptide | -0.0331184 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0329158 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.032694 |
| CDK13 | cyclin-dependent kinase 13 | -0.0325804 |
| CCNI | cyclin I | -0.0325747 |
| POTEF | POTE ankyrin domain family, member F | -0.0322564 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.032037 |
| NDRG1 | N-myc downstream regulated 1 | -0.0317529 |
| VIM | vimentin | -0.0317176 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0314719 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0310608 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0307181 |
| RLF | rearranged L-myc fusion | -0.0305025 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0302437 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0302079 |
| PGM3 | phosphoglucomutase 3 | -0.0298496 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0297484 |
| NOP58 | NOP58 ribonucleoprotein | -0.0296926 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0294255 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0293636 |
| RAB7A | RAB7A, member RAS oncogene family | -0.028884 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0287654 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0285118 |
| SKIC3 | SKI3 subunit of superkiller complex | -0.028461 |
| GOLGB1 | golgin B1 | -0.0283665 |
| FAF2 | Fas associated factor family member 2 | -0.0283608 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0283179 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0279178 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0278332 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0277328 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0276105 |
| NABP1 | nucleic acid binding protein 1 | -0.0275453 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0275439 |
| CD109 | CD109 molecule | -0.0274912 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0274693 |
| RARS1 | arginyl-tRNA synthetase 1 | -0.0273012 |
| UBC | ubiquitin C | -0.0271077 |
| CANX | calnexin | -0.0270898 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0270859 |
| PRRC1 | proline-rich coiled-coil 1 | -0.026973 |
| RTN4 | reticulon 4 | -0.0269291 |
| MYO9A | myosin IXA | -0.0267838 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0267643 |
| WASF2 | WAS protein family, member 2 | -0.0267632 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0267517 |
| TFG | TRK-fused gene | -0.0267221 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0266605 |
| RNF145 | ring finger protein 145 | -0.0266437 |
| MYADM | myeloid-associated differentiation marker | -0.0263588 |
| CCDC88A | coiled-coil domain containing 88A | -0.0263274 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0262901 |
| DSTN | destrin (actin depolymerizing factor) | -0.0257205 |
| YIPF5 | Yip1 domain family, member 5 | -0.0257158 |
| ELP2 | elongator acetyltransferase complex subunit 2 | -0.0254786 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0247968 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0247391 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0247216 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0246597 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0246157 |
| RBM39 | RNA binding motif protein 39 | -0.0245507 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0245256 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0245187 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.024496 |
