| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Riluzole hydrochloride perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Riluzole hydrochloride_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DST | dystonin | 0.123373 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.092937 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0927555 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0859843 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0832467 |
| SMAD3 | SMAD family member 3 | 0.0763666 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0751159 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0749647 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0701402 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0664267 |
| ANGPTL4 | angiopoietin-like 4 | 0.0659567 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.065739 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0654043 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0647335 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0647264 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0642555 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0633314 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0585018 |
| HMGA2 | high mobility group AT-hook 2 | 0.058057 |
| LDHA | lactate dehydrogenase A | 0.0578071 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0571694 |
| PLEC | plectin | 0.0562925 |
| FMNL2 | formin-like 2 | 0.0558957 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0553279 |
| CEP250 | centrosomal protein 250kDa | 0.0547149 |
| COL5A1 | collagen, type V, alpha 1 | 0.0530999 |
| TMSB10 | thymosin beta 10 | 0.0529876 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.052133 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.05034 |
| PRSS23 | protease, serine, 23 | 0.0502874 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0496781 |
| FLNA | filamin A, alpha | 0.0485369 |
| ACTN1 | actinin, alpha 1 | 0.0473057 |
| FLNB | filamin B, beta | 0.0470474 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0457769 |
| MSN | moesin | 0.0449451 |
| PRKCA | protein kinase C, alpha | 0.0448931 |
| MYO9B | myosin IXB | 0.0439409 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0439118 |
| ITGB4 | integrin, beta 4 | 0.0428928 |
| STEAP3 | STEAP family member 3, metalloreductase | 0.0410272 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0408963 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0406527 |
| ANO6 | anoctamin 6 | 0.0406234 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0403519 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0400869 |
| B2M | beta-2-microglobulin | 0.039818 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0396539 |
| AHNAK | AHNAK nucleoprotein | 0.0394211 |
| ATXN1 | ataxin 1 | 0.0392445 |
| PKM | pyruvate kinase, muscle | 0.0389375 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0385168 |
| POTEF | POTE ankyrin domain family, member F | 0.0385139 |
| SVIL | supervillin | 0.0384735 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0383931 |
| CAPRIN2 | caprin family member 2 | 0.038101 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0378912 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.037684 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0375769 |
| CD44 | CD44 molecule (Indian blood group) | 0.0368698 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0367928 |
| PCED1B | PC-esterase domain containing 1B | 0.0354919 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0353099 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0351014 |
| PODXL | podocalyxin-like | 0.0350789 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0348129 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0347747 |
| JUN | jun proto-oncogene | 0.0346275 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0343265 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0343075 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0339543 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0337871 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0337295 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0335719 |
| PRR16 | proline rich 16 | 0.0334858 |
| NAV2 | neuron navigator 2 | 0.0332552 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0330142 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.032953 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0329517 |
| NONO | non-POU domain containing, octamer-binding | 0.0327417 |
| PYGL | phosphorylase, glycogen, liver | 0.0327316 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0325264 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0315121 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0313655 |
| INTS6 | integrator complex subunit 6 | 0.0307485 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0303035 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0300212 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0298944 |
| EGFR | epidermal growth factor receptor | 0.0298371 |
| SDC4 | syndecan 4 | 0.0297368 |
| CMIP | c-Maf inducing protein | 0.0295414 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.028838 |
| ASPH | aspartate beta-hydroxylase | 0.0284233 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0282951 |
| HLA-B | major histocompatibility complex, class I, B | 0.0282945 |
| RIGI | RNA sensor RIG-I | 0.0281941 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0280221 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0279663 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0279043 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0276175 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.266141 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0819575 |
| ZNF292 | zinc finger protein 292 | -0.0758238 |
| RBM39 | RNA binding motif protein 39 | -0.0660417 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0611626 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0545752 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.053981 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0530415 |
| GOLGA4 | golgin A4 | -0.0462511 |
| TPX2 | TPX2, microtubule-associated | -0.045487 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0443766 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0434162 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0421012 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0415919 |
| KIAA1958 | KIAA1958 | -0.0399414 |
| MATR3 | matrin 3 | -0.0395224 |
| VIM | vimentin | -0.0392896 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0388543 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0384215 |
| NUP58 | nucleoporin 58 | -0.0381421 |
| ANLN | anillin, actin binding protein | -0.0366403 |
| GNAS | GNAS complex locus | -0.0362772 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.035542 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0347255 |
| CENPF | centromere protein F, 350/400kDa | -0.0341094 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.033682 |
| DIAPH3 | diaphanous-related formin 3 | -0.0325073 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0322832 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.032163 |
| ECT2 | epithelial cell transforming 2 | -0.031612 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0309463 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0309449 |
| OSMR | oncostatin M receptor | -0.0307113 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0306917 |
| WDR45B | WD repeat domain 45B | -0.0305652 |
| KIAA1328 | KIAA1328 | -0.0302113 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.030085 |
| RPL4 | ribosomal protein L4 | -0.0296743 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0294694 |
| SGO2 | shugoshin 2 | -0.0290051 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0283749 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0278472 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0277218 |
| SNX14 | sorting nexin 14 | -0.0273619 |
| COG5 | component of oligomeric golgi complex 5 | -0.027066 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | -0.0269942 |
| JMJD1C | jumonji domain containing 1C | -0.0269143 |
| DNER | delta/notch-like EGF repeat containing | -0.0268774 |
| PAPOLA | poly(A) polymerase alpha | -0.0267764 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0264139 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.02621 |
| SRP54 | signal recognition particle 54kDa | -0.0261659 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0258907 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0258003 |
| PTMA | prothymosin, alpha | -0.0257433 |
| RPL23 | ribosomal protein L23 | -0.0256577 |
| CUL5 | cullin 5 | -0.0253541 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0253427 |
| DEK | DEK proto-oncogene | -0.0252811 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0251638 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0249319 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0248337 |
| NOP58 | NOP58 ribonucleoprotein | -0.0248081 |
| NKTR | natural killer cell triggering receptor | -0.0247643 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0247373 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0242852 |
| TPM4 | tropomyosin 4 | -0.0241347 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0240925 |
| SEPTIN7 | septin 7 | -0.0240435 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | -0.0239248 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0237823 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0237726 |
| AHCTF1 | AT hook containing transcription factor 1 | -0.0237427 |
| TTK | TTK protein kinase | -0.0234827 |
| CCDC138 | coiled-coil domain containing 138 | -0.0234106 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | -0.0233361 |
| CEP95 | centrosomal protein 95kDa | -0.0231175 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0230821 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0229762 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | -0.0229333 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0228449 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0227079 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0226622 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.02248 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0224474 |
| NUP98 | nucleoporin 98kDa | -0.0222997 |
| TLK1 | tousled-like kinase 1 | -0.0219763 |
| CANX | calnexin | -0.0219565 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0217043 |
| RAD18 | RAD18 E3 ubiquitin protein ligase | -0.0217009 |
| HMGB1 | high mobility group box 1 | -0.021693 |
| CLINT1 | clathrin interactor 1 | -0.0215346 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0215077 |
| RPL30 | ribosomal protein L30 | -0.0213606 |
| SEC24A | SEC24 family member A | -0.0213476 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0213057 |
| MED17 | mediator complex subunit 17 | -0.0210849 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0209689 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0208654 |
| ATP13A3 | ATPase type 13A3 | -0.0207888 |
