| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Riluzole hydrochloride perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Riluzole hydrochloride_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.182773 |
| YBX3 | Y box binding protein 3 | 0.089393 |
| B2M | beta-2-microglobulin | 0.0752827 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0722758 |
| HLA-B | major histocompatibility complex, class I, B | 0.0722278 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0700893 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0640925 |
| TMSB10 | thymosin beta 10 | 0.0631824 |
| LMNA | lamin A/C | 0.0615611 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0611996 |
| GLIS3 | GLIS family zinc finger 3 | 0.0593994 |
| MT2A | metallothionein 2A | 0.0570578 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0560505 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0544114 |
| TXNIP | thioredoxin interacting protein | 0.0529435 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0524794 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0520679 |
| SMAD3 | SMAD family member 3 | 0.0507723 |
| TMSB4X | thymosin beta 4, X-linked | 0.0500652 |
| SQSTM1 | sequestosome 1 | 0.0482676 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0458141 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0453647 |
| AOPEP | aminopeptidase O (putative) | 0.0453492 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0452393 |
| OSMR | oncostatin M receptor | 0.045032 |
| RNF213 | ring finger protein 213 | 0.0448663 |
| ETV1 | ets variant 1 | 0.0432703 |
| TXNRD1 | thioredoxin reductase 1 | 0.0427311 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.0421451 |
| FOXP1 | forkhead box P1 | 0.0413497 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0410914 |
| RUNX2 | runt-related transcription factor 2 | 0.0404713 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0403245 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0398041 |
| PELO | pelota homolog (Drosophila) | 0.0392482 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0383011 |
| SON | SON DNA binding protein | 0.0372348 |
| ASPH | aspartate beta-hydroxylase | 0.0368081 |
| PGK1 | phosphoglycerate kinase 1 | 0.0356698 |
| SVIL | supervillin | 0.0342402 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0339917 |
| SYNJ2 | synaptojanin 2 | 0.0329855 |
| SFTPA2 | surfactant protein A2 | 0.0326457 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0323724 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0317742 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0317331 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0314958 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0313072 |
| CD44 | CD44 molecule (Indian blood group) | 0.030833 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0301878 |
| TPR | translocated promoter region, nuclear basket protein | 0.0298227 |
| CAB39 | calcium binding protein 39 | 0.0297242 |
| FTL | ferritin, light polypeptide | 0.0292189 |
| EREG | epiregulin | 0.0288015 |
| MT1X | metallothionein 1X | 0.0284713 |
| HLA-C | major histocompatibility complex, class I, C | 0.0284707 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.027792 |
| HLA-A | major histocompatibility complex, class I, A | 0.0276445 |
| SMOX | spermine oxidase | 0.0275009 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0272566 |
| LDHA | lactate dehydrogenase A | 0.027213 |
| NDRG1 | N-myc downstream regulated 1 | 0.0266477 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0265783 |
| RPL35A | ribosomal protein L35a | 0.0261992 |
| SDC4 | syndecan 4 | 0.0261809 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0261425 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.026076 |
| SSH1 | slingshot protein phosphatase 1 | 0.0249077 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.0246104 |
| CEP250 | centrosomal protein 250kDa | 0.0243231 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0242624 |
| BCL3 | B-cell CLL/lymphoma 3 | 0.0239905 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0239582 |
| RPL37 | ribosomal protein L37 | 0.0239021 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0238556 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0234642 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.0227762 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0227443 |
| FNBP1 | formin binding protein 1 | 0.0226631 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0225417 |
| FLNA | filamin A, alpha | 0.0221981 |
| NRP1 | neuropilin 1 | 0.0221292 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0219553 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0219072 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0218886 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0218233 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0218205 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0217891 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | 0.0216994 |
| NONO | non-POU domain containing, octamer-binding | 0.0215706 |
| KSR1 | kinase suppressor of ras 1 | 0.0215621 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0213227 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.021261 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0209307 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0208955 |
| AHR | aryl hydrocarbon receptor | 0.0208796 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0208202 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0206958 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0204655 |
| RNF149 | ring finger protein 149 | 0.0203113 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.221297 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.186717 |
| FN1 | fibronectin 1 | -0.154783 |
| NRG1 | neuregulin 1 | -0.141508 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.134916 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.110899 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.104347 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.102219 |
| CANX | calnexin | -0.0886071 |
| VCL | vinculin | -0.0757386 |
| EFNA5 | ephrin-A5 | -0.0716434 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0713637 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0708933 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0685897 |
| PTMA | prothymosin, alpha | -0.0650361 |
| RAI14 | retinoic acid induced 14 | -0.0603711 |
| CADM1 | cell adhesion molecule 1 | -0.0598058 |
| PALLD | palladin, cytoskeletal associated protein | -0.0588915 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0587791 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0586088 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0585401 |
| HMGA2 | high mobility group AT-hook 2 | -0.0569601 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0553915 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0514942 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0483184 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0478594 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0440922 |
| STC2 | stanniocalcin 2 | -0.0439117 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0438773 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0437661 |
| TMEM165 | transmembrane protein 165 | -0.0433461 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0426584 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0421333 |
| PLIN2 | perilipin 2 | -0.0413667 |
| ERO1B | endoplasmic reticulum oxidoreductase 1 beta | -0.0383769 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0377229 |
| POTEF | POTE ankyrin domain family, member F | -0.0368125 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.036507 |
| ITGA1 | integrin, alpha 1 | -0.0362924 |
| LRRC23 | leucine rich repeat containing 23 | -0.0357325 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0356157 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0350004 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0349915 |
| INTS6 | integrator complex subunit 6 | -0.0349581 |
| FBXW11 | F-box and WD repeat domain containing 11 | -0.0344167 |
| GOLGA4 | golgin A4 | -0.0341674 |
| AEBP2 | AE binding protein 2 | -0.0332924 |
| CEP350 | centrosomal protein 350kDa | -0.0332277 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0331717 |
| FNIP1 | folliculin interacting protein 1 | -0.0328321 |
| UBAP1 | ubiquitin associated protein 1 | -0.0328004 |
| AHNAK | AHNAK nucleoprotein | -0.0326482 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0320822 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0308866 |
| LOX | lysyl oxidase | -0.030849 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0307369 |
| CTSD | cathepsin D | -0.0305957 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0305822 |
| TPM4 | tropomyosin 4 | -0.0299779 |
| CDK13 | cyclin-dependent kinase 13 | -0.0298844 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0290273 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0288615 |
| VMP1 | vacuole membrane protein 1 | -0.0286989 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0284452 |
| RCOR1 | REST corepressor 1 | -0.0281487 |
| LOXL2 | lysyl oxidase-like 2 | -0.0280897 |
| NUMB | numb homolog (Drosophila) | -0.0274284 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0274039 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0272101 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0267739 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0267054 |
| SNX14 | sorting nexin 14 | -0.0264126 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0262374 |
| CENPF | centromere protein F, 350/400kDa | -0.0262218 |
| IER3 | immediate early response 3 | -0.0261939 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0261202 |
| RASAL2 | RAS protein activator like 2 | -0.026107 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0260624 |
| MCU | mitochondrial calcium uniporter | -0.0260454 |
| FAM114A1 | family with sequence similarity 114, member A1 | -0.0259651 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0258249 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0255059 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0252834 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0252074 |
| ACTG1 | actin gamma 1 | -0.0251771 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0250642 |
| SUCO | SUN domain containing ossification factor | -0.024893 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0248314 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0247682 |
| RTN3 | reticulon 3 | -0.0247581 |
| GNAS | GNAS complex locus | -0.024713 |
| UBAP2 | ubiquitin associated protein 2 | -0.0247076 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0245276 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0243535 |
| FLNB | filamin B, beta | -0.0242938 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0242771 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0242364 |
| TOR1AIP2 | torsin A interacting protein 2 | -0.0241256 |
| HDLBP | high density lipoprotein binding protein | -0.0240345 |
| YME1L1 | YME1-like 1 ATPase | -0.023804 |
