| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Riluzole hydrochloride perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Riluzole hydrochloride_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| BCL2L1 | BCL2-like 1 | 0.195884 |
| KRT8 | keratin 8, type II | 0.155479 |
| KRT18 | keratin 18, type I | 0.147097 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.115349 |
| MACC1 | metastasis associated in colon cancer 1 | 0.100305 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0967049 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0963737 |
| FAT1 | FAT atypical cadherin 1 | 0.0959482 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.094841 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0909714 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0898793 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0731958 |
| LDHA | lactate dehydrogenase A | 0.0720588 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0703352 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0703213 |
| NEBL | nebulette | 0.0686326 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0616067 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0612309 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.059551 |
| NONO | non-POU domain containing, octamer-binding | 0.0593037 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0589893 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0579219 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0577165 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0551607 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0533048 |
| ANXA11 | annexin A11 | 0.0530522 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0529979 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0524152 |
| DSPP | dentin sialophosphoprotein | 0.0515621 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0509916 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0509481 |
| PLEC | plectin | 0.0504671 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0504328 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0487755 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0468664 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0455635 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0453305 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0449963 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0438035 |
| PGK1 | phosphoglycerate kinase 1 | 0.0436698 |
| PRELID3B | PRELI domain containing 3B | 0.0430835 |
| MKRN1 | makorin ring finger protein 1 | 0.0428023 |
| B2M | beta-2-microglobulin | 0.0418649 |
| RPL3 | ribosomal protein L3 | 0.0418607 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0411913 |
| MYOF | myoferlin | 0.0409659 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0407705 |
| SON | SON DNA binding protein | 0.0397411 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0391466 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0383979 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0381781 |
| MED15 | mediator complex subunit 15 | 0.0379698 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0377728 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0372189 |
| HYOU1 | hypoxia up-regulated 1 | 0.036994 |
| MX2 | MX dynamin-like GTPase 2 | 0.036944 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0364131 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0360473 |
| SVIL | supervillin | 0.036034 |
| ETV6 | ets variant 6 | 0.0355179 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0349516 |
| CEP250 | centrosomal protein 250kDa | 0.0349299 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0348789 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0345281 |
| CD9 | CD9 molecule | 0.0343422 |
| YAP1 | Yes-associated protein 1 | 0.034158 |
| CTBP2 | C-terminal binding protein 2 | 0.0331661 |
| DIAPH1 | diaphanous-related formin 1 | 0.0331437 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0327872 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.032673 |
| BLCAP | bladder cancer associated protein | 0.032668 |
| VEGFA | vascular endothelial growth factor A | 0.032329 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0322288 |
| CALR | calreticulin | 0.0321083 |
| SMAD3 | SMAD family member 3 | 0.0314764 |
| FTL | ferritin, light polypeptide | 0.0312473 |
| MYO5B | myosin VB | 0.031182 |
| EXOC4 | exocyst complex component 4 | 0.0308096 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0307996 |
| APP | amyloid beta (A4) precursor protein | 0.0307555 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0303658 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0303497 |
| SET | SET nuclear proto-oncogene | 0.0301594 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0301475 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0301407 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | 0.029951 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.029768 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0296111 |
| TJP1 | tight junction protein 1 | 0.0295642 |
| HDLBP | high density lipoprotein binding protein | 0.0294554 |
| CMIP | c-Maf inducing protein | 0.028665 |
| AMOTL2 | angiomotin like 2 | 0.0283542 |
| TMEM41B | transmembrane protein 41B | 0.0282146 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0278551 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.027832 |
| CUX1 | cut-like homeobox 1 | 0.0277927 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0277136 |
| MKI67 | marker of proliferation Ki-67 | 0.0276304 |
| NFIA | nuclear factor I/A | 0.027437 |
| DCUN1D3 | DCN1, defective in cullin neddylation 1, domain containing 3 | 0.0273838 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.12782 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.111799 |
| GNAS | GNAS complex locus | -0.0773527 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0546956 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0511129 |
| RBM39 | RNA binding motif protein 39 | -0.0505867 |
| CCND1 | cyclin D1 | -0.0488774 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0480608 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0468968 |
| IER3 | immediate early response 3 | -0.0453664 |
| S100A10 | S100 calcium binding protein A10 | -0.0451083 |
| ZNF292 | zinc finger protein 292 | -0.0449774 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0442549 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.044197 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0438166 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0429015 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0424442 |
| RYBP | RING1 and YY1 binding protein | -0.0412988 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0411312 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0405265 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0404732 |
| H1-0 | H1.0 linker histone | -0.0401543 |
| SQSTM1 | sequestosome 1 | -0.0399102 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0396985 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0387406 |
| INTS6 | integrator complex subunit 6 | -0.0368696 |
| TMEM123 | transmembrane protein 123 | -0.0362914 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0357908 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0346773 |
| ZNF207 | zinc finger protein 207 | -0.034251 |
| ANXA2 | annexin A2 | -0.0340428 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0321602 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0315739 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0306965 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -0.030327 |
| CCNL1 | cyclin L1 | -0.0303204 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.029833 |
| NOP58 | NOP58 ribonucleoprotein | -0.0295989 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0294311 |
| TFRC | transferrin receptor | -0.0291217 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0284029 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.02832 |
| CDK13 | cyclin-dependent kinase 13 | -0.0282723 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0280985 |
| MATR3 | matrin 3 | -0.0280707 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0268422 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0268286 |
| PERP | PERP, TP53 apoptosis effector | -0.0257572 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0255086 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0251116 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0249826 |
| SEPTIN7 | septin 7 | -0.0249511 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0248961 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0248641 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0248567 |
| GTF2B | general transcription factor IIB | -0.0244226 |
| VMP1 | vacuole membrane protein 1 | -0.0236669 |
| RPS6 | ribosomal protein S6 | -0.0236652 |
| RPS11 | ribosomal protein S11 | -0.0235942 |
| RYK | receptor-like tyrosine kinase | -0.0233286 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.023227 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0231686 |
| RPL32 | ribosomal protein L32 | -0.0229945 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0228717 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0228409 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0227397 |
| RASA2 | RAS p21 protein activator 2 | -0.0225689 |
| RPL8 | ribosomal protein L8 | -0.0225639 |
| HBP1 | HMG-box transcription factor 1 | -0.0224994 |
| USP3 | ubiquitin specific peptidase 3 | -0.0224294 |
| CUL3 | cullin 3 | -0.0223523 |
| HMGA1 | high mobility group AT-hook 1 | -0.0220247 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0218732 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.021706 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0216277 |
| PAPOLA | poly(A) polymerase alpha | -0.0213892 |
| ARF1 | ADP-ribosylation factor 1 | -0.0212474 |
| MEF2A | myocyte enhancer factor 2A | -0.0209938 |
| OLA1 | Obg-like ATPase 1 | -0.0209531 |
| DEK | DEK proto-oncogene | -0.0208225 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0206479 |
| NCOA3 | nuclear receptor coactivator 3 | -0.020633 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0206022 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0205187 |
| HMGB1 | high mobility group box 1 | -0.020494 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0202872 |
| OGA | O-GlcNAcase | -0.0201952 |
| UBE2D1 | ubiquitin-conjugating enzyme E2D 1 | -0.0200565 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0199832 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0198984 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0197328 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.019657 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.0195842 |
| RPS15 | ribosomal protein S15 | -0.0195676 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | -0.0195551 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.01946 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0194133 |
| FBXO11 | F-box protein 11 | -0.0193831 |
| PDS5B | PDS5 cohesin associated factor B | -0.019377 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0192987 |
