| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Riluzole hydrochloride perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Riluzole hydrochloride_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.19097 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.140971 |
| HSPA8 | heat shock 70kDa protein 8 | 0.112447 |
| LAMB3 | laminin, beta 3 | 0.0979034 |
| EZR | ezrin | 0.0963615 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0960054 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0952965 |
| FAT1 | FAT atypical cadherin 1 | 0.0945021 |
| EGFR | epidermal growth factor receptor | 0.0914452 |
| RPL3 | ribosomal protein L3 | 0.0854617 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0813984 |
| ATXN1 | ataxin 1 | 0.0748752 |
| LAMC2 | laminin, gamma 2 | 0.0724677 |
| LMO7 | LIM domain 7 | 0.0714464 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.068742 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0655739 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0638665 |
| AHNAK | AHNAK nucleoprotein | 0.0637007 |
| DSPP | dentin sialophosphoprotein | 0.0609218 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0564605 |
| ACTG1 | actin gamma 1 | 0.05565 |
| EPHA2 | EPH receptor A2 | 0.0547333 |
| PLEC | plectin | 0.0507448 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0494179 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0487289 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0485921 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.048586 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0472979 |
| SEPTIN9 | septin 9 | 0.0471723 |
| CTSB | cathepsin B | 0.0470607 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0448808 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0447246 |
| SMAD3 | SMAD family member 3 | 0.0438584 |
| FLNA | filamin A, alpha | 0.0424789 |
| RNF43 | ring finger protein 43 | 0.0419094 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0415078 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0409242 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0406189 |
| AXIN2 | axin 2 | 0.0404085 |
| ANXA1 | annexin A1 | 0.0402376 |
| CENPF | centromere protein F, 350/400kDa | 0.03936 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0391122 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0388766 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0381208 |
| NONO | non-POU domain containing, octamer-binding | 0.0372001 |
| RPS4X | ribosomal protein S4, X-linked | 0.0363663 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0359554 |
| DOCK5 | dedicator of cytokinesis 5 | 0.03569 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | 0.0352988 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0352565 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0351988 |
| BMP4 | bone morphogenetic protein 4 | 0.0349603 |
| MKI67 | marker of proliferation Ki-67 | 0.0349027 |
| TMSB10 | thymosin beta 10 | 0.0342536 |
| KRT8 | keratin 8, type II | 0.033811 |
| PFKP | phosphofructokinase, platelet | 0.0337743 |
| SNX9 | sorting nexin 9 | 0.0333838 |
| BCL2L1 | BCL2-like 1 | 0.0327022 |
| DUSP4 | dual specificity phosphatase 4 | 0.0319143 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0318213 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0316516 |
| DST | dystonin | 0.0314263 |
| ANXA11 | annexin A11 | 0.0304707 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0304487 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.0302811 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0300491 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0297417 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0297157 |
| TES | testin LIM domain protein | 0.0297102 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0295768 |
| EMP1 | epithelial membrane protein 1 | 0.0292492 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0290844 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0290072 |
| CD9 | CD9 molecule | 0.0288722 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0287515 |
| ACTN4 | actinin, alpha 4 | 0.0285564 |
| APP | amyloid beta (A4) precursor protein | 0.0280229 |
| RPL4 | ribosomal protein L4 | 0.0279709 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.0279549 |
| NIBAN2 | niban apoptosis regulator 2 | 0.027843 |
| SFTPA2 | surfactant protein A2 | 0.027819 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0277169 |
| IGSF9B | immunoglobulin superfamily, member 9B | 0.0273201 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | 0.0266411 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0266218 |
| H1-2 | H1.2 linker histone, cluster member | 0.0265221 |
| YBX3 | Y box binding protein 3 | 0.0262459 |
| HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 | 0.02613 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0255854 |
| MYO5B | myosin VB | 0.0254494 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0249088 |
| JUN | jun proto-oncogene | 0.02474 |
| FHL2 | four and a half LIM domains 2 | 0.0246595 |
| HDLBP | high density lipoprotein binding protein | 0.0245982 |
| CEP250 | centrosomal protein 250kDa | 0.0245935 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0245777 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0242725 |
| HMGB2 | high mobility group box 2 | 0.0240838 |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 | 0.023856 |
| SON | SON DNA binding protein | 0.0237145 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.171426 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0836839 |
| PTMA | prothymosin, alpha | -0.0812576 |
| RPS6 | ribosomal protein S6 | -0.0752391 |
| IER3 | immediate early response 3 | -0.0722304 |
| RPS29 | ribosomal protein S29 | -0.0635654 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0632926 |
| RPS8 | ribosomal protein S8 | -0.062881 |
| GPHN | gephyrin | -0.0608428 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0582763 |
| RPL37A | ribosomal protein L37a | -0.057384 |
| RPS23 | ribosomal protein S23 | -0.0527375 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0503725 |
| FLOT1 | flotillin 1 | -0.0500551 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0477049 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0470568 |
| FHIT | fragile histidine triad | -0.0447259 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0438436 |
| RPS13 | ribosomal protein S13 | -0.04201 |
| RPLP1 | ribosomal protein, large, P1 | -0.0416561 |
| SETD5 | SET domain containing 5 | -0.0407492 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0406181 |
| RPS25 | ribosomal protein S25 | -0.0405767 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0404282 |
| CDK13 | cyclin-dependent kinase 13 | -0.0397147 |
| RPS12 | ribosomal protein S12 | -0.0384047 |
| RPS15 | ribosomal protein S15 | -0.0372525 |
| RCOR1 | REST corepressor 1 | -0.0372364 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0372093 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0366995 |
| GDF15 | growth differentiation factor 15 | -0.0363774 |
| COG5 | component of oligomeric golgi complex 5 | -0.0363083 |
| MAP4 | microtubule-associated protein 4 | -0.0361965 |
| RPL31 | ribosomal protein L31 | -0.0352062 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.033503 |
| RPS24 | ribosomal protein S24 | -0.0331991 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0322962 |
| FBXO11 | F-box protein 11 | -0.0320424 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0317719 |
| RPL35A | ribosomal protein L35a | -0.0317457 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0316201 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0304593 |
| RPS11 | ribosomal protein S11 | -0.0303844 |
| RPL5 | ribosomal protein L5 | -0.0301804 |
| FTL | ferritin, light polypeptide | -0.0299122 |
| SBF2 | SET binding factor 2 | -0.029883 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0291564 |
| PARD3 | par-3 family cell polarity regulator | -0.0291223 |
| HDAC2 | histone deacetylase 2 | -0.0289554 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.028723 |
| RPL8 | ribosomal protein L8 | -0.0286329 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0285779 |
| RPLP2 | ribosomal protein, large, P2 | -0.0284694 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0276991 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0257341 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0255164 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0254098 |
| RPL32 | ribosomal protein L32 | -0.0251505 |
| RPS27A | ribosomal protein S27a | -0.0251474 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0251235 |
| CUX1 | cut-like homeobox 1 | -0.025083 |
| RPS5 | ribosomal protein S5 | -0.0250534 |
| RPS2 | ribosomal protein S2 | -0.0246027 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0236896 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.023672 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0235771 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.023416 |
| DIAPH2 | diaphanous-related formin 2 | -0.0232087 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0226253 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0225905 |
| RPS17 | ribosomal protein S17 | -0.0225778 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.022277 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0218421 |
| SCFD1 | sec1 family domain containing 1 | -0.0218376 |
| GPC5 | glypican 5 | -0.0215247 |
| GOLGA4 | golgin A4 | -0.0213229 |
| SKAP1 | src kinase associated phosphoprotein 1 | -0.0210805 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.02092 |
| RPL34 | ribosomal protein L34 | -0.0208887 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0208407 |
| HMGA1 | high mobility group AT-hook 1 | -0.0206288 |
| RPL12 | ribosomal protein L12 | -0.0206266 |
| BPTF | bromodomain PHD finger transcription factor | -0.0205629 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0204512 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0203768 |
| RPL9 | ribosomal protein L9 | -0.0201202 |
| RPS16 | ribosomal protein S16 | -0.0199589 |
| TXNIP | thioredoxin interacting protein | -0.0197654 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0195709 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0194834 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0194149 |
| NDRG1 | N-myc downstream regulated 1 | -0.0193768 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0193733 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0193187 |
| ARMH4 | armadillo like helical domain containing 4 | -0.0192006 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0191554 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0190982 |
| UBAP2 | ubiquitin associated protein 2 | -0.0187871 |
| MTDH | metadherin | -0.0187248 |
| RPL7A | ribosomal protein L7a | -0.0187127 |
