| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Riluzole hydrochloride perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Riluzole hydrochloride_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.415875 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.190601 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.160775 |
| STC1 | stanniocalcin 1 | 0.143008 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.114196 |
| ACTG1 | actin gamma 1 | 0.0922219 |
| HLA-B | major histocompatibility complex, class I, B | 0.0903942 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0899593 |
| MYO10 | myosin X | 0.089928 |
| B2M | beta-2-microglobulin | 0.0858521 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0842755 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0833479 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0791641 |
| SMAD3 | SMAD family member 3 | 0.0769342 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0640519 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0612842 |
| CD44 | CD44 molecule (Indian blood group) | 0.0550955 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0541454 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0527684 |
| NAV1 | neuron navigator 1 | 0.0524523 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.04927 |
| COL1A2 | collagen, type I, alpha 2 | 0.0491242 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0485546 |
| MSN | moesin | 0.0465356 |
| RUNX1 | runt-related transcription factor 1 | 0.0461926 |
| FAM13A | family with sequence similarity 13, member A | 0.0457688 |
| NDRG1 | N-myc downstream regulated 1 | 0.0455197 |
| MAP1B | microtubule-associated protein 1B | 0.0447571 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0427016 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0417419 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0410545 |
| VEGFA | vascular endothelial growth factor A | 0.0391719 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0389319 |
| FRMD6 | FERM domain containing 6 | 0.038624 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0383109 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0381698 |
| LDHA | lactate dehydrogenase A | 0.0376813 |
| MT2A | metallothionein 2A | 0.0372585 |
| COL5A3 | collagen, type V, alpha 3 | 0.0371942 |
| TMSB4X | thymosin beta 4, X-linked | 0.0363647 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0353219 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0343483 |
| FAT1 | FAT atypical cadherin 1 | 0.0338437 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0334835 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0333421 |
| TNS1 | tensin 1 | 0.0332929 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0330697 |
| HLA-A | major histocompatibility complex, class I, A | 0.0303796 |
| FLNA | filamin A, alpha | 0.0303564 |
| CALU | calumenin | 0.0298728 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0293641 |
| SFTPA2 | surfactant protein A2 | 0.0292443 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0287373 |
| RPL3 | ribosomal protein L3 | 0.0284771 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0281865 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0281147 |
| ITGA11 | integrin, alpha 11 | 0.0280323 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0277079 |
| CALR | calreticulin | 0.0277077 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0275525 |
| NONO | non-POU domain containing, octamer-binding | 0.0268414 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.026686 |
| SEPTIN9 | septin 9 | 0.0263525 |
| LOXL2 | lysyl oxidase-like 2 | 0.0262855 |
| APP | amyloid beta (A4) precursor protein | 0.0262134 |
| FOXP1 | forkhead box P1 | 0.0259658 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0259473 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0258109 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0256758 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0250695 |
| ANXA2 | annexin A2 | 0.0249144 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0247117 |
| HSPA8 | heat shock 70kDa protein 8 | 0.024657 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0236108 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0233514 |
| KLF12 | Kruppel-like factor 12 | 0.0232594 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0232475 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0230842 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0228244 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0223047 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0222997 |
| SON | SON DNA binding protein | 0.0221584 |
| TLN1 | talin 1 | 0.0221147 |
| HLA-C | major histocompatibility complex, class I, C | 0.021734 |
| BRD2 | bromodomain containing 2 | 0.0216913 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0215536 |
| ACTN1 | actinin, alpha 1 | 0.0214327 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0214141 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0208911 |
| COL5A1 | collagen, type V, alpha 1 | 0.0208787 |
| PKM | pyruvate kinase, muscle | 0.0208685 |
| DST | dystonin | 0.0207862 |
| LMNA | lamin A/C | 0.020665 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.0203578 |
| SMTN | smoothelin | 0.0203111 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0202992 |
| TPM3 | tropomyosin 3 | 0.019961 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0198727 |
| WLS | wntless Wnt ligand secretion mediator | 0.0198355 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0198092 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.226669 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.135752 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.134923 |
| INHBA | inhibin, beta A | -0.132519 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.123253 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0827021 |
| OXR1 | oxidation resistance 1 | -0.0809445 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.076522 |
| MMP1 | matrix metallopeptidase 1 | -0.0743777 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0702001 |
| FN1 | fibronectin 1 | -0.0695718 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0685573 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0642679 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0564967 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0537061 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0523926 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.051053 |
| AHNAK | AHNAK nucleoprotein | -0.0484906 |
| MMP12 | matrix metallopeptidase 12 | -0.0483747 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0476841 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0441907 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0421175 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0400007 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0399632 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0393761 |
| GOLGA4 | golgin A4 | -0.0393209 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0391749 |
| HMGA2 | high mobility group AT-hook 2 | -0.0372432 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0366513 |
| NCKAP5 | NCK-associated protein 5 | -0.0364541 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0354211 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.0350616 |
| TTC23L | tetratricopeptide repeat domain 23-like | -0.0329793 |
| DIAPH2 | diaphanous-related formin 2 | -0.0311795 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0310582 |
| TMEM165 | transmembrane protein 165 | -0.0309274 |
| RAI14 | retinoic acid induced 14 | -0.0303808 |
| COL5A2 | collagen, type V, alpha 2 | -0.0303551 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0302819 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0294052 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0290915 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.029014 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0280755 |
| TMEM263 | transmembrane protein 263 | -0.0278773 |
| SBF2 | SET binding factor 2 | -0.0266416 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0262876 |
| VCAN | versican | -0.0261148 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0257339 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0250809 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0248259 |
| PRRX1 | paired related homeobox 1 | -0.0245266 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0243728 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0241302 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0238148 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.0236733 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0235306 |
| GPATCH2L | G patch domain containing 2-like | -0.0233979 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0233637 |
| NBEAL1 | neurobeachin-like 1 | -0.0231167 |
| GOLGB1 | golgin B1 | -0.0231044 |
| H1-0 | H1.0 linker histone | -0.0229063 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0223759 |
| CDH13 | cadherin 13 | -0.0222255 |
| PGM3 | phosphoglucomutase 3 | -0.0218723 |
| MAP4 | microtubule-associated protein 4 | -0.0217265 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0215769 |
| FNDC3A | fibronectin type III domain containing 3A | -0.021487 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0213375 |
| LOX | lysyl oxidase | -0.0211909 |
| EMP1 | epithelial membrane protein 1 | -0.0211341 |
| VIM | vimentin | -0.0211165 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0209466 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0208346 |
| MEIS1 | Meis homeobox 1 | -0.020573 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0204295 |
| DNER | delta/notch-like EGF repeat containing | -0.0204258 |
| ITGA1 | integrin, alpha 1 | -0.0203571 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0203464 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.020331 |
| VCL | vinculin | -0.0201787 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0197362 |
| SRP54 | signal recognition particle 54kDa | -0.0197068 |
| NREP | neuronal regeneration related protein | -0.019531 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0191397 |
| EGFR | epidermal growth factor receptor | -0.0191123 |
| MYSM1 | Myb-like, SWIRM and MPN domains 1 | -0.019066 |
| PHF3 | PHD finger protein 3 | -0.0189173 |
| COG6 | component of oligomeric golgi complex 6 | -0.0184646 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0183501 |
| RPS6 | ribosomal protein S6 | -0.0182237 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0181342 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.018017 |
| FBN2 | fibrillin 2 | -0.0179486 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0175066 |
| HDLBP | high density lipoprotein binding protein | -0.0172959 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | -0.017196 |
| CFDP1 | craniofacial development protein 1 | -0.0171572 |
| NABP1 | nucleic acid binding protein 1 | -0.0170464 |
| RAD51B | RAD51 paralog B | -0.0169855 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0169778 |
