| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rimonabant (Hydrochloride) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rimonabant (Hydrochloride)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.133572 |
| FBN1 | fibrillin 1 | 0.0940041 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0869807 |
| OGA | O-GlcNAcase | 0.0827709 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0715405 |
| FNDC3B | fibronectin type III domain containing 3B | 0.069073 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0658802 |
| UBC | ubiquitin C | 0.0622626 |
| PTMA | prothymosin, alpha | 0.0596532 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.057014 |
| ATP13A3 | ATPase type 13A3 | 0.0562517 |
| LOXL2 | lysyl oxidase-like 2 | 0.053966 |
| SQSTM1 | sequestosome 1 | 0.0537852 |
| COL3A1 | collagen, type III, alpha 1 | 0.0536995 |
| MT2A | metallothionein 2A | 0.0534292 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0524852 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0504289 |
| SBF2 | SET binding factor 2 | 0.0503131 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0495805 |
| COL1A2 | collagen, type I, alpha 2 | 0.0494134 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0479031 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0464887 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.046378 |
| GPC6 | glypican 6 | 0.0448756 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0437349 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0412365 |
| NAV2 | neuron navigator 2 | 0.041057 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0410144 |
| AUTS2 | autism susceptibility candidate 2 | 0.0393499 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.039275 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0391713 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0390253 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0389658 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0383998 |
| STC1 | stanniocalcin 1 | 0.038274 |
| GOLGA4 | golgin A4 | 0.0375112 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0370501 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | 0.0368339 |
| OPTN | optineurin | 0.0365701 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0365647 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0364539 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.03627 |
| APP | amyloid beta (A4) precursor protein | 0.035879 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0358132 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0354225 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0353378 |
| FMNL2 | formin-like 2 | 0.0344819 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0343979 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0343025 |
| HIP1 | huntingtin interacting protein 1 | 0.0342384 |
| WTAP | Wilms tumor 1 associated protein | 0.0341697 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0340185 |
| FLNB | filamin B, beta | 0.033565 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0320971 |
| XPO1 | exportin 1 | 0.032049 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0318398 |
| HELZ | helicase with zinc finger | 0.0317565 |
| INSIG2 | insulin induced gene 2 | 0.0314877 |
| DENND5A | DENN/MADD domain containing 5A | 0.0312087 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0310003 |
| RNF24 | ring finger protein 24 | 0.0309264 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.030198 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0301089 |
| ARRDC3 | arrestin domain containing 3 | 0.0299163 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0298873 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0295681 |
| SEPTIN9 | septin 9 | 0.0295248 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0293527 |
| SETD5 | SET domain containing 5 | 0.0289486 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0289248 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0285834 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0285201 |
| ZNF292 | zinc finger protein 292 | 0.0282855 |
| CD109 | CD109 molecule | 0.0281629 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0281167 |
| COL5A2 | collagen, type V, alpha 2 | 0.0278311 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0276815 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0272642 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0271652 |
| NGLY1 | N-glycanase 1 | 0.0270897 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0270432 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0269313 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0268762 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0268652 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0268385 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.02664 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.026579 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0265269 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0259504 |
| RNF145 | ring finger protein 145 | 0.0257027 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0254397 |
| SDC4 | syndecan 4 | 0.0254079 |
| YEATS2 | YEATS domain containing 2 | 0.0252645 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0251651 |
| FNIP1 | folliculin interacting protein 1 | 0.0251284 |
| TMOD1 | tropomodulin 1 | 0.0249855 |
| AHNAK | AHNAK nucleoprotein | 0.0248131 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0247692 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0245084 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0244943 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.245173 |
| PODXL | podocalyxin-like | -0.176891 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.157435 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.146352 |
| VIM | vimentin | -0.136858 |
| CDH13 | cadherin 13 | -0.122747 |
| MAP1B | microtubule-associated protein 1B | -0.120046 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.106813 |
| FN1 | fibronectin 1 | -0.10335 |
| TMSB10 | thymosin beta 10 | -0.0966376 |
| COL5A1 | collagen, type V, alpha 1 | -0.0962255 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0757653 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0735039 |
| NAV1 | neuron navigator 1 | -0.0709706 |
| SUCNR1 | succinate receptor 1 | -0.0660285 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0659603 |
| EGFR | epidermal growth factor receptor | -0.0611857 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0518162 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0479773 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0474463 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0463946 |
| PRSS23 | protease, serine, 23 | -0.0455188 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0441283 |
| EFNA5 | ephrin-A5 | -0.0439705 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0435266 |
| DGKG | diacylglycerol kinase, gamma 90kDa | -0.0416022 |
| TAGLN2 | transgelin 2 | -0.0412406 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0381081 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0379112 |
| LOX | lysyl oxidase | -0.037807 |
| CYTH3 | cytohesin 3 | -0.0376491 |
| PLXNA2 | plexin A2 | -0.036648 |
| POTEF | POTE ankyrin domain family, member F | -0.0361159 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0349275 |
| ASPH | aspartate beta-hydroxylase | -0.0343511 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.033285 |
| RIGI | RNA sensor RIG-I | -0.0327878 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0324567 |
| DCLK2 | doublecortin-like kinase 2 | -0.0320154 |
| PLAT | plasminogen activator, tissue | -0.0315273 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0313421 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0308127 |
| LRRC17 | leucine rich repeat containing 17 | -0.0302705 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0293654 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0290312 |
| S100A10 | S100 calcium binding protein A10 | -0.0290078 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0284014 |
| MX2 | MX dynamin-like GTPase 2 | -0.0278461 |
| CUX1 | cut-like homeobox 1 | -0.0276136 |
| RASAL2 | RAS protein activator like 2 | -0.0275394 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0273492 |
| CSTB | cystatin B (stefin B) | -0.0273107 |
| CCND1 | cyclin D1 | -0.0269981 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0269626 |
| PKM | pyruvate kinase, muscle | -0.0268935 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0264937 |
| KRT81 | keratin 81, type II | -0.0263171 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0261235 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0260344 |
| IL7R | interleukin 7 receptor | -0.0258331 |
| FMN2 | formin 2 | -0.0256202 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | -0.0255156 |
| PCDH7 | protocadherin 7 | -0.0252546 |
| KIAA1549L | KIAA1549-like | -0.0251799 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0249403 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.02454 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0241114 |
| LOC112694756 | uncharaterized LOC112694756 | -0.023675 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0231069 |
| S100A6 | S100 calcium binding protein A6 | -0.022908 |
| FSTL1 | follistatin-like 1 | -0.0228324 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0224181 |
| PFN1 | profilin 1 | -0.0223629 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0222542 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.0219924 |
| RNF213 | ring finger protein 213 | -0.0219863 |
| FLNA | filamin A, alpha | -0.0219466 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0219224 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.021263 |
| VCL | vinculin | -0.0212498 |
| SP100 | SP100 nuclear antigen | -0.0208923 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0207187 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0200761 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0199991 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0199398 |
| TPM4 | tropomyosin 4 | -0.0197538 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0195506 |
| MYADM | myeloid-associated differentiation marker | -0.0195205 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0193267 |
| MSN | moesin | -0.0190597 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0189981 |
| FRMD4A | FERM domain containing 4A | -0.0188529 |
| TPM1 | tropomyosin 1 (alpha) | -0.018775 |
| L1CAM | L1 cell adhesion molecule | -0.0187169 |
| FNDC3A | fibronectin type III domain containing 3A | -0.018639 |
| S100A11 | S100 calcium binding protein A11 | -0.0185038 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0184918 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0184084 |
| INTS6 | integrator complex subunit 6 | -0.0180931 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0178774 |