| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rimonabant (Hydrochloride) perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rimonabant (Hydrochloride)_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VEGFA | vascular endothelial growth factor A | 0.0843435 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0827374 |
| TMSB4X | thymosin beta 4, X-linked | 0.0652838 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0626803 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0620626 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0602855 |
| OGA | O-GlcNAcase | 0.0596753 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0593273 |
| AHNAK | AHNAK nucleoprotein | 0.0568285 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0551605 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0536161 |
| ZNF292 | zinc finger protein 292 | 0.0504941 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0500087 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0477924 |
| SET | SET nuclear proto-oncogene | 0.0471561 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0449448 |
| WDR45B | WD repeat domain 45B | 0.0442982 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0438508 |
| HMGB2 | high mobility group box 2 | 0.0426274 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0420452 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0414666 |
| FMNL2 | formin-like 2 | 0.0413877 |
| PGK1 | phosphoglycerate kinase 1 | 0.041072 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.041027 |
| SPAG9 | sperm associated antigen 9 | 0.0402773 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0402124 |
| RBM25 | RNA binding motif protein 25 | 0.03843 |
| XPO1 | exportin 1 | 0.0379716 |
| UTRN | utrophin | 0.0376541 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0374927 |
| TOP1 | topoisomerase (DNA) I | 0.0372795 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0369444 |
| ASPH | aspartate beta-hydroxylase | 0.0366105 |
| DST | dystonin | 0.036295 |
| KLHDC10 | kelch domain containing 10 | 0.0362651 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.0355172 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0355109 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0354036 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0354018 |
| PDGFC | platelet derived growth factor C | 0.0348302 |
| SPAG5 | sperm associated antigen 5 | 0.0346848 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.0345584 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0345019 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0344028 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0343221 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.03381 |
| PTMA | prothymosin, alpha | 0.0337668 |
| CALD1 | caldesmon 1 | 0.0327841 |
| MKI67 | marker of proliferation Ki-67 | 0.0326411 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0324182 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0322943 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0318652 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0318543 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0317158 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0316886 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0316153 |
| PLEKHA7 | pleckstrin homology domain containing, family A member 7 | 0.0314315 |
| GOLGA4 | golgin A4 | 0.0312938 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0311869 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0311726 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0307551 |
| PHF3 | PHD finger protein 3 | 0.0303066 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0294006 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0293901 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0293633 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0291393 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0290576 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0290192 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0289973 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0289606 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0288029 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0284948 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0281448 |
| RNF145 | ring finger protein 145 | 0.0279797 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0278438 |
| ANLN | anillin, actin binding protein | 0.0276461 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0276243 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0274714 |
| EXOC4 | exocyst complex component 4 | 0.0271997 |
| RREB1 | ras responsive element binding protein 1 | 0.0271501 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0269822 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0268499 |
| RPL4 | ribosomal protein L4 | 0.0268306 |
| WDR26 | WD repeat domain 26 | 0.0266055 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0265915 |
| CHD3 | chromodomain helicase DNA binding protein 3 | 0.0263828 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0263474 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0261478 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0260742 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0259165 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0257774 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0257559 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0256996 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0255805 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0255351 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0252684 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0248859 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0248629 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | 0.0247157 |
| YEATS2 | YEATS domain containing 2 | 0.0246547 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.210999 |
| MEST | mesoderm specific transcript | -0.210762 |
| VIM | vimentin | -0.206654 |
| RPLP1 | ribosomal protein, large, P1 | -0.087206 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0850333 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0807502 |
| PEG10 | paternally expressed 10 | -0.0787122 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0717244 |
| HMGA1 | high mobility group AT-hook 1 | -0.0644635 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0612974 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0606979 |
| RPL11 | ribosomal protein L11 | -0.0552877 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0503349 |
| EGR1 | early growth response 1 | -0.0499779 |
| RPL35A | ribosomal protein L35a | -0.0473939 |
| RPS24 | ribosomal protein S24 | -0.0466674 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0466379 |
| RPS6 | ribosomal protein S6 | -0.0454806 |
| NFIB | nuclear factor I/B | -0.0437699 |
| TUBB | tubulin, beta class I | -0.043223 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0428563 |
| PKM | pyruvate kinase, muscle | -0.0413046 |
| RPL34 | ribosomal protein L34 | -0.0403369 |
| SIK3 | SIK family kinase 3 | -0.0399585 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.03984 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0395646 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0387572 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0384028 |
| HMGA2 | high mobility group AT-hook 2 | -0.0380975 |
| JMJD1C | jumonji domain containing 1C | -0.0378344 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.0375166 |
| RPLP0 | ribosomal protein, large, P0 | -0.0367591 |
| PCM1 | pericentriolar material 1 | -0.0365724 |
| ERBIN | erbb2 interacting protein | -0.0365713 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0362425 |
| VCL | vinculin | -0.036049 |
| RPS20 | ribosomal protein S20 | -0.0360035 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0349792 |
| IGF2 | insulin-like growth factor 2 | -0.0348732 |
| FTL | ferritin, light polypeptide | -0.0348245 |
| MGP | matrix Gla protein | -0.0346623 |
| PALLD | palladin, cytoskeletal associated protein | -0.0340043 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0338755 |
| POTEF | POTE ankyrin domain family, member F | -0.0335365 |
| LDHA | lactate dehydrogenase A | -0.0323977 |
| RANBP17 | RAN binding protein 17 | -0.0321741 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0321661 |
| GSE1 | Gse1 coiled-coil protein | -0.0316816 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0314955 |
| DOCK3 | dedicator of cytokinesis 3 | -0.0312706 |
| RPL12 | ribosomal protein L12 | -0.0308604 |
| S100A9 | S100 calcium binding protein A9 | -0.03071 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0303232 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | -0.0299578 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0299532 |
| RPL28 | ribosomal protein L28 | -0.0293714 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0288614 |
| FAM193A | family with sequence similarity 193, member A | -0.0285607 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | -0.0280154 |
| PDS5A | PDS5 cohesin associated factor A | -0.0277755 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0274267 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0271461 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | -0.0268997 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0268315 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0268217 |
| MAP1B | microtubule-associated protein 1B | -0.026805 |
| GATAD2A | GATA zinc finger domain containing 2A | -0.0260266 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0259228 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0258506 |
| RPS19 | ribosomal protein S19 | -0.0255145 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0254969 |
| RACK1 | receptor for activated C kinase 1 | -0.0254799 |
| RDX | radixin | -0.0253396 |
| RPL30 | ribosomal protein L30 | -0.0253057 |
| NBEA | neurobeachin | -0.0252912 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0250325 |
| PDE10A | phosphodiesterase 10A | -0.0250309 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0246776 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0244631 |
| CLINT1 | clathrin interactor 1 | -0.0243929 |
| RPS5 | ribosomal protein S5 | -0.0242305 |
| RPL36 | ribosomal protein L36 | -0.0242164 |
| GLG1 | golgi glycoprotein 1 | -0.0242159 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0240369 |
| B2M | beta-2-microglobulin | -0.0239683 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0233792 |
| RPL32 | ribosomal protein L32 | -0.0232722 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0231959 |
| RPS2 | ribosomal protein S2 | -0.0231787 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0228289 |
| HIP1 | huntingtin interacting protein 1 | -0.0227006 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0226717 |
| CRY1 | cryptochrome circadian clock 1 | -0.0226713 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.0226124 |
| SIN3A | SIN3 transcription regulator family member A | -0.0224505 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0224466 |
| TMEM87A | transmembrane protein 87A | -0.0224262 |
| SLMAP | sarcolemma associated protein | -0.0223251 |
| SHOC2 | soc-2 suppressor of clear homolog (C. elegans) | -0.0221863 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0221126 |
