| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rimonabant (Hydrochloride) perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rimonabant (Hydrochloride)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VMP1 | vacuole membrane protein 1 | 0.159199 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.104825 |
| CEP250 | centrosomal protein 250kDa | 0.0778362 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.0632038 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0618963 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0616472 |
| ANKRD36C | ankyrin repeat domain 36C | 0.060049 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0593346 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0531868 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0497477 |
| GRB10 | growth factor receptor-bound protein 10 | 0.048861 |
| VEGFA | vascular endothelial growth factor A | 0.0469803 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0460864 |
| SRCIN1 | SRC kinase signaling inhibitor 1 | 0.0426464 |
| KIF16B | kinesin family member 16B | 0.0397723 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0388247 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0386804 |
| PTK2 | protein tyrosine kinase 2 | 0.0382806 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0373657 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0366733 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0361089 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0358176 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0354371 |
| PLSCR1 | phospholipid scramblase 1 | 0.0347839 |
| DTNA | dystrobrevin, alpha | 0.0343849 |
| USP53 | ubiquitin specific peptidase 53 | 0.0341251 |
| MSI2 | musashi RNA-binding protein 2 | 0.0336711 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0328447 |
| CCNL1 | cyclin L1 | 0.0325935 |
| KIAA1217 | KIAA1217 | 0.0325288 |
| MCL1 | myeloid cell leukemia 1 | 0.0313923 |
| PRELID2 | PRELI domain containing 2 | 0.0305639 |
| ANLN | anillin, actin binding protein | 0.0305167 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0303617 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0303271 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0302381 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0300347 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0299617 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0289563 |
| RAD51B | RAD51 paralog B | 0.0289148 |
| SHROOM3 | shroom family member 3 | 0.0288626 |
| SP100 | SP100 nuclear antigen | 0.0279592 |
| CCNY | cyclin Y | 0.0279446 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0276548 |
| EFNA5 | ephrin-A5 | 0.0275305 |
| BBX | bobby sox homolog (Drosophila) | 0.0271191 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0264977 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0262029 |
| MYO1B | myosin IB | 0.0260683 |
| YEATS2 | YEATS domain containing 2 | 0.0258497 |
| RTN4 | reticulon 4 | 0.0257086 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0253555 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0248195 |
| TOM1L1 | target of myb1 (chicken)-like 1 | 0.0246965 |
| RBM39 | RNA binding motif protein 39 | 0.0246797 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0241689 |
| MYO5B | myosin VB | 0.0237247 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0236388 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0235907 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.0235434 |
| APP | amyloid beta (A4) precursor protein | 0.0234937 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0234926 |
| YAP1 | Yes-associated protein 1 | 0.0229411 |
| TMEM165 | transmembrane protein 165 | 0.0229407 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | 0.0229341 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.022934 |
| DST | dystonin | 0.0226517 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0223548 |
| PNN | pinin, desmosome associated protein | 0.0223049 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0221999 |
| EXOC4 | exocyst complex component 4 | 0.0221731 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0220646 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0219959 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0219634 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.0219262 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0218292 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0216768 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0213712 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0212954 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0212706 |
| VCL | vinculin | 0.0212657 |
| OSMR | oncostatin M receptor | 0.0211625 |
| AFDN | afadin, adherens junction formation factor | 0.021022 |
| GSE1 | Gse1 coiled-coil protein | 0.0209245 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.02075 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0207486 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.02069 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0206035 |
| FOXO3 | forkhead box O3 | 0.020501 |
| TPM3 | tropomyosin 3 | 0.0202505 |
| ATP13A3 | ATPase type 13A3 | 0.0201298 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.020099 |
| FAM168A | family with sequence similarity 168, member A | 0.0200073 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0199209 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0198964 |
| ECT2 | epithelial cell transforming 2 | 0.0196801 |
| CEP192 | centrosomal protein 192kDa | 0.0194806 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0191742 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0190973 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0190794 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL19 | ribosomal protein L19 | -0.194681 |
| RPL23 | ribosomal protein L23 | -0.186763 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.134778 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.134685 |
| ACTG1 | actin gamma 1 | -0.106435 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.102575 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.091978 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0784317 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0781115 |
| CDK12 | cyclin-dependent kinase 12 | -0.0715394 |
| CCND1 | cyclin D1 | -0.0685337 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0663317 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -0.0637538 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0628914 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0607291 |
| CCNI | cyclin I | -0.0584598 |
| TMSB10 | thymosin beta 10 | -0.0564374 |
| RPL35A | ribosomal protein L35a | -0.0561959 |
| LASP1 | LIM and SH3 protein 1 | -0.0529721 |
| LOC112694756 | uncharaterized LOC112694756 | -0.04842 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0462221 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0455364 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | -0.0422669 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0417964 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0410305 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0407618 |
| MT2A | metallothionein 2A | -0.0391114 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0385234 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0377958 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0373498 |
| INTS6 | integrator complex subunit 6 | -0.037325 |
| KRT19 | keratin 19, type I | -0.0372077 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0369215 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0364689 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0360857 |
| SMIM14 | small integral membrane protein 14 | -0.0358139 |
| CLTC | clathrin, heavy chain (Hc) | -0.034604 |
| GRB7 | growth factor receptor-bound protein 7 | -0.0342036 |
| RPS8 | ribosomal protein S8 | -0.0337743 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0333419 |
| RPLP1 | ribosomal protein, large, P1 | -0.0332332 |
| HDLBP | high density lipoprotein binding protein | -0.0329168 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | -0.0325276 |
| S100A9 | S100 calcium binding protein A9 | -0.0324824 |
| TMEM123 | transmembrane protein 123 | -0.0323872 |
| RPLP0 | ribosomal protein, large, P0 | -0.0319486 |
| SDC4 | syndecan 4 | -0.0309304 |
| RPS3 | ribosomal protein S3 | -0.0303322 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0302735 |
| S100A14 | S100 calcium binding protein A14 | -0.0302543 |
| MBD4 | methyl-CpG binding domain protein 4 | -0.029953 |
| RPL12 | ribosomal protein L12 | -0.0296864 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.0294971 |
| MLLT6 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 | -0.0293245 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0290515 |
| GDPD1 | glycerophosphodiester phosphodiesterase domain containing 1 | -0.0289169 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0288027 |
| ASPH | aspartate beta-hydroxylase | -0.0283319 |
| IER3 | immediate early response 3 | -0.0283199 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.028047 |
| B2M | beta-2-microglobulin | -0.0279107 |
| RPS6 | ribosomal protein S6 | -0.0277859 |
| GNAS | GNAS complex locus | -0.0269183 |
| RPL8 | ribosomal protein L8 | -0.0262084 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | -0.026038 |
| BPTF | bromodomain PHD finger transcription factor | -0.0258321 |
| ZNF217 | zinc finger protein 217 | -0.0254591 |
| RPL32 | ribosomal protein L32 | -0.0253996 |
| MTDH | metadherin | -0.0253609 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0253134 |
| FTL | ferritin, light polypeptide | -0.0245842 |
| RPL34 | ribosomal protein L34 | -0.0244989 |
| PFN1 | profilin 1 | -0.0243979 |
| LMNA | lamin A/C | -0.0241062 |
| GOLGB1 | golgin B1 | -0.0240589 |
| SERF2 | small EDRK-rich factor 2 | -0.0238093 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0237386 |
| NCOA6 | nuclear receptor coactivator 6 | -0.0236637 |
| PFDN4 | prefoldin subunit 4 | -0.0235122 |
| LDHA | lactate dehydrogenase A | -0.0231388 |
| RPS19 | ribosomal protein S19 | -0.022989 |
| PKM | pyruvate kinase, muscle | -0.0228865 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0228122 |
| MIEN1 | migration and invasion enhancer 1 | -0.0226519 |
| TPI1 | triosephosphate isomerase 1 | -0.0226058 |
| CADPS2 | Ca++-dependent secretion activator 2 | -0.022536 |
| AHNAK | AHNAK nucleoprotein | -0.0225174 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0224418 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0224117 |
| RPS16 | ribosomal protein S16 | -0.0222989 |
| RAB14 | RAB14, member RAS oncogene family | -0.0222937 |
| POTEF | POTE ankyrin domain family, member F | -0.0219408 |
| S100A11 | S100 calcium binding protein A11 | -0.0218268 |
| HRNR | hornerin | -0.0216763 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0215117 |
| SDCBP | syndecan binding protein (syntenin) | -0.0214735 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0214641 |
| TC2N | tandem C2 domains, nuclear | -0.0212977 |
| RACK1 | receptor for activated C kinase 1 | -0.0210511 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0209684 |
