| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rimonabant (Hydrochloride) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rimonabant (Hydrochloride)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.149283 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.122582 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.103811 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0973841 |
| ASPH | aspartate beta-hydroxylase | 0.085542 |
| VIM | vimentin | 0.0806545 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.078138 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0770487 |
| MT2A | metallothionein 2A | 0.0762609 |
| AHNAK | AHNAK nucleoprotein | 0.0579434 |
| APP | amyloid beta (A4) precursor protein | 0.0556052 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0532477 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0523564 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0510961 |
| INSIG1 | insulin induced gene 1 | 0.0455591 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0455248 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0451835 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0434657 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0432961 |
| SFTPA2 | surfactant protein A2 | 0.0410205 |
| RHEB | Ras homolog enriched in brain | 0.0400867 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0396076 |
| RPS12 | ribosomal protein S12 | 0.0394424 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0393045 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.039303 |
| ANXA2 | annexin A2 | 0.0391684 |
| SMAD3 | SMAD family member 3 | 0.0388357 |
| RPLP1 | ribosomal protein, large, P1 | 0.0387239 |
| PTMA | prothymosin, alpha | 0.0386772 |
| CALU | calumenin | 0.0382293 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0379814 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0370981 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0367604 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0363425 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0363283 |
| S100A6 | S100 calcium binding protein A6 | 0.0354545 |
| MRTFA | myocardin related transcription factor A | 0.03532 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0342124 |
| SEPTIN9 | septin 9 | 0.0337118 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0333826 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0331746 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0327555 |
| RPS8 | ribosomal protein S8 | 0.0324229 |
| ACTG1 | actin gamma 1 | 0.0323133 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0315768 |
| NEK7 | NIMA-related kinase 7 | 0.0314393 |
| CALR | calreticulin | 0.0306235 |
| SEPTIN7 | septin 7 | 0.0306184 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0296876 |
| RYBP | RING1 and YY1 binding protein | 0.0293825 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0289712 |
| NAV1 | neuron navigator 1 | 0.0287304 |
| HMGB2 | high mobility group box 2 | 0.0286396 |
| S100A9 | S100 calcium binding protein A9 | 0.0282334 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0279624 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0279577 |
| PHF21A | PHD finger protein 21A | 0.02724 |
| RPS3 | ribosomal protein S3 | 0.026874 |
| S100A10 | S100 calcium binding protein A10 | 0.0262736 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0262522 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0260319 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0259556 |
| MKI67 | marker of proliferation Ki-67 | 0.0257712 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0254866 |
| RPL12 | ribosomal protein L12 | 0.0254361 |
| B2M | beta-2-microglobulin | 0.0254181 |
| UBC | ubiquitin C | 0.0253597 |
| PKM | pyruvate kinase, muscle | 0.0252824 |
| PGK1 | phosphoglycerate kinase 1 | 0.0252099 |
| YBX3 | Y box binding protein 3 | 0.0251178 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0244391 |
| LDHA | lactate dehydrogenase A | 0.0241562 |
| RPL37A | ribosomal protein L37a | 0.0241061 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0239203 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0237476 |
| ATXN1 | ataxin 1 | 0.0232377 |
| RPL19 | ribosomal protein L19 | 0.0232315 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0229185 |
| RPS19 | ribosomal protein S19 | 0.0227783 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0227671 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0227261 |
| IER3 | immediate early response 3 | 0.022642 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0225288 |
| CD63 | CD63 molecule | 0.022095 |
| RPL4 | ribosomal protein L4 | 0.0220612 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0220559 |
| CORO1C | coronin, actin binding protein, 1C | 0.0220274 |
| ANKRD10 | ankyrin repeat domain 10 | 0.021982 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0219752 |
| YBX1 | Y box binding protein 1 | 0.02191 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0219067 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0218645 |
| AFAP1 | actin filament associated protein 1 | 0.0218444 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0218324 |
| RBM33 | RNA binding motif protein 33 | 0.0218202 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0218083 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0217456 |
| MYOF | myoferlin | 0.021529 |
| LMNA | lamin A/C | 0.0215287 |
| ANXA5 | annexin A5 | 0.0213912 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.462145 |
| NDRG1 | N-myc downstream regulated 1 | -0.119946 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0957038 |
| GPC6 | glypican 6 | -0.0951713 |
| EGR1 | early growth response 1 | -0.0835398 |
| GDF15 | growth differentiation factor 15 | -0.0800984 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0697001 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.067789 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0651716 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0640951 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0578825 |
| EHBP1 | EH domain binding protein 1 | -0.0574069 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0564579 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0553322 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0531077 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0523082 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0520071 |
| PTCHD4 | patched domain containing 4 | -0.0495194 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0451751 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0448735 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.043502 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.042967 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0427717 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0425628 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0425231 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0411009 |
| AHCYL2 | adenosylhomocysteinase-like 2 | -0.0397965 |
| OXR1 | oxidation resistance 1 | -0.039783 |
| COL19A1 | collagen, type XIX, alpha 1 | -0.0396658 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0395909 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0384799 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0383234 |
| PLIN2 | perilipin 2 | -0.0375289 |
| SCFD2 | sec1 family domain containing 2 | -0.0360255 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.036 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.035491 |
| TMEM123 | transmembrane protein 123 | -0.0352695 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0351073 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0347921 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0345723 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.033744 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0337132 |
| PRKD1 | protein kinase D1 | -0.0337099 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0335177 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.033081 |
| TRIM2 | tripartite motif containing 2 | -0.033048 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.030667 |
| LAMB1 | laminin, beta 1 | -0.0305826 |
| SEC24A | SEC24 family member A | -0.0304532 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0301376 |
| SBF2 | SET binding factor 2 | -0.0300394 |
| RUNX1 | runt-related transcription factor 1 | -0.029863 |
| VCL | vinculin | -0.0282554 |
| NF1 | neurofibromin 1 | -0.0277679 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0276166 |
| HMGA2 | high mobility group AT-hook 2 | -0.0275549 |
| STXBP1 | syntaxin binding protein 1 | -0.0273743 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0272989 |
| NBAS | neuroblastoma amplified sequence | -0.0272616 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0272254 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0264796 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0263982 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0262222 |
| IGF2 | insulin-like growth factor 2 | -0.0255486 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.0254987 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.02527 |
| GHR | growth hormone receptor | -0.0251026 |
| CTTNBP2 | cortactin binding protein 2 | -0.0243538 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0241771 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0241581 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0239482 |
| HIP1 | huntingtin interacting protein 1 | -0.0236711 |
| ITGB8 | integrin, beta 8 | -0.0229634 |
| A2M | alpha-2-macroglobulin | -0.0227407 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0227048 |
| ADAM19 | ADAM metallopeptidase domain 19 | -0.0226979 |
| CUX1 | cut-like homeobox 1 | -0.0226596 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0223304 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0222084 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0218939 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | -0.021819 |
| ADM | adrenomedullin | -0.021474 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0213397 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0213352 |
| NBEA | neurobeachin | -0.0212565 |
| JAZF1 | JAZF zinc finger 1 | -0.0211305 |
| FNIP1 | folliculin interacting protein 1 | -0.0209444 |
| TXNIP | thioredoxin interacting protein | -0.0207848 |
| PYGB | phosphorylase, glycogen; brain | -0.0207331 |
| POM121C | POM121 transmembrane nucleoporin C | -0.0207235 |
| NPR2 | natriuretic peptide receptor 2 | -0.0206538 |
| NAV3 | neuron navigator 3 | -0.020479 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0204747 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0203945 |
| CCDC91 | coiled-coil domain containing 91 | -0.0203641 |
| CDH19 | cadherin 19, type 2 | -0.0203613 |
| UBE3C | ubiquitin protein ligase E3C | -0.0199428 |
| SERINC5 | serine incorporator 5 | -0.0199348 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0197829 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.0197446 |
