| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rimonabant (Hydrochloride) perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rimonabant (Hydrochloride)_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VEGFA | vascular endothelial growth factor A | 0.150201 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0930295 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0876148 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0776498 |
| CADM1 | cell adhesion molecule 1 | 0.0763859 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.066901 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0620739 |
| ATP13A3 | ATPase type 13A3 | 0.0563232 |
| PTMA | prothymosin, alpha | 0.0556808 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0548542 |
| PTK2 | protein tyrosine kinase 2 | 0.0539668 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0508755 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0478295 |
| CALR | calreticulin | 0.0460672 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0450004 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0438313 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0410051 |
| NAV2 | neuron navigator 2 | 0.0381081 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0373725 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0372712 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0370823 |
| SMAD3 | SMAD family member 3 | 0.0370764 |
| USP3 | ubiquitin specific peptidase 3 | 0.0353949 |
| FMNL2 | formin-like 2 | 0.0352838 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0344327 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0341969 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0340366 |
| MATR3 | matrin 3 | 0.0330351 |
| TMSB4X | thymosin beta 4, X-linked | 0.0329542 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0313285 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0313165 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0306073 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0298646 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.029237 |
| OGA | O-GlcNAcase | 0.0289001 |
| ARRDC3 | arrestin domain containing 3 | 0.0285993 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0284475 |
| RPL3 | ribosomal protein L3 | 0.0280257 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0278731 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0273534 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0272003 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0271519 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0271174 |
| MRTFA | myocardin related transcription factor A | 0.0263681 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0255452 |
| VCAN | versican | 0.0247664 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0243972 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.023651 |
| FAM168A | family with sequence similarity 168, member A | 0.0234153 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0233386 |
| PRELID2 | PRELI domain containing 2 | 0.0232852 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0232395 |
| RPL7 | ribosomal protein L7 | 0.0229856 |
| INSIG2 | insulin induced gene 2 | 0.0225132 |
| PDE8A | phosphodiesterase 8A | 0.0223395 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0222522 |
| ZNF292 | zinc finger protein 292 | 0.0222179 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0221819 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0219543 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0218765 |
| TNS1 | tensin 1 | 0.0218356 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0216726 |
| UBC | ubiquitin C | 0.021568 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0211745 |
| FAT1 | FAT atypical cadherin 1 | 0.0208202 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0207856 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0207145 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0205304 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0200805 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0198565 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0197107 |
| RLF | rearranged L-myc fusion | 0.0194285 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0192888 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0192425 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.019124 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0190216 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0188884 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0188059 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0185352 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0184867 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.018468 |
| RPL4 | ribosomal protein L4 | 0.0184511 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0182963 |
| QKI | QKI, KH domain containing, RNA binding | 0.0182598 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0182593 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0180514 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0178945 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0178007 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0176313 |
| COPA | coatomer protein complex, subunit alpha | 0.0174907 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0174435 |
| RBM39 | RNA binding motif protein 39 | 0.0174378 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0171553 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0171035 |
| RNF24 | ring finger protein 24 | 0.0170919 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0170186 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0169742 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0169262 |
| RHOA | ras homolog family member A | 0.0169173 |
| RPL14 | ribosomal protein L14 | 0.0169126 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.496119 |
| FN1 | fibronectin 1 | -0.342616 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.259569 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.140598 |
| NDRG1 | N-myc downstream regulated 1 | -0.0947796 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0928157 |
| LOX | lysyl oxidase | -0.0831618 |
| COL1A2 | collagen, type I, alpha 2 | -0.0662631 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0646956 |
| GLIS3 | GLIS family zinc finger 3 | -0.0603914 |
| ACTG1 | actin gamma 1 | -0.0600225 |
| MT2A | metallothionein 2A | -0.0588867 |
| VIM | vimentin | -0.0580342 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0529429 |
| RPL35A | ribosomal protein L35a | -0.0492915 |
| EGR1 | early growth response 1 | -0.0468225 |
| PALLD | palladin, cytoskeletal associated protein | -0.0467285 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0465338 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0459874 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0440108 |
| HLA-B | major histocompatibility complex, class I, B | -0.0439158 |
| HMGA2 | high mobility group AT-hook 2 | -0.043899 |
| VCL | vinculin | -0.0409377 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0402366 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0397642 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0391462 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0387022 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0386577 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0385457 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0377206 |
| ZNF644 | zinc finger protein 644 | -0.0360033 |
| MAP1B | microtubule-associated protein 1B | -0.0348188 |
| GOLGB1 | golgin B1 | -0.0337977 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0331254 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.032189 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0319174 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0318706 |
| TMSB10 | thymosin beta 10 | -0.0314649 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0304971 |
| OSMR | oncostatin M receptor | -0.0298163 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0292544 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0274178 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0268752 |
| POSTN | periostin, osteoblast specific factor | -0.0262732 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0261536 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0255203 |
| CALD1 | caldesmon 1 | -0.0254882 |
| LDHA | lactate dehydrogenase A | -0.0248907 |
| INHBA | inhibin, beta A | -0.0245903 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0242978 |
| NABP1 | nucleic acid binding protein 1 | -0.0242786 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0241587 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0238788 |
| MT1X | metallothionein 1X | -0.0235496 |
| FBN1 | fibrillin 1 | -0.0233059 |
| RSU1 | Ras suppressor protein 1 | -0.0232389 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0231753 |
| HMGA1 | high mobility group AT-hook 1 | -0.0228272 |
| RAB7A | RAB7A, member RAS oncogene family | -0.022249 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0222408 |
| MYADM | myeloid-associated differentiation marker | -0.0218681 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0215587 |
| STC1 | stanniocalcin 1 | -0.0213432 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0208805 |
| CMIP | c-Maf inducing protein | -0.020619 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0204349 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0203977 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0203051 |
| TAGLN2 | transgelin 2 | -0.0199124 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.019631 |
| S100A6 | S100 calcium binding protein A6 | -0.0193397 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0190227 |
| BPTF | bromodomain PHD finger transcription factor | -0.0188045 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0184191 |
| DUSP6 | dual specificity phosphatase 6 | -0.0181733 |
| RAB2A | RAB2A, member RAS oncogene family | -0.018164 |
| CCND1 | cyclin D1 | -0.0181176 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0180086 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0176864 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0175307 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.017421 |
| HLA-A | major histocompatibility complex, class I, A | -0.017266 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.017111 |
| COL3A1 | collagen, type III, alpha 1 | -0.0169958 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0167736 |
| B2M | beta-2-microglobulin | -0.0167567 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0165442 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0165249 |
| AHI1 | Abelson helper integration site 1 | -0.0164522 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0164414 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0163973 |
| COL1A1 | collagen, type I, alpha 1 | -0.0163838 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0161981 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.01619 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.01614 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.01606 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0160503 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0160429 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0160205 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0158512 |
