| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rimonabant (Hydrochloride) perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rimonabant (Hydrochloride)_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.114492 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.111838 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.103134 |
| RPL4 | ribosomal protein L4 | 0.0967747 |
| PTMA | prothymosin, alpha | 0.0926327 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0876422 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0846992 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0644595 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0629859 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0547275 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0511313 |
| KRT18 | keratin 18, type I | 0.0504852 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0465316 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0457133 |
| RPS27A | ribosomal protein S27a | 0.0434987 |
| PRELID2 | PRELI domain containing 2 | 0.041161 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0408905 |
| OGA | O-GlcNAcase | 0.0407727 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0406579 |
| MED13L | mediator complex subunit 13-like | 0.04021 |
| DENND1A | DENN/MADD domain containing 1A | 0.0402091 |
| RNF145 | ring finger protein 145 | 0.0399781 |
| RPL3 | ribosomal protein L3 | 0.0380201 |
| RPL14 | ribosomal protein L14 | 0.0374656 |
| RPS3 | ribosomal protein S3 | 0.0372281 |
| KRT8 | keratin 8, type II | 0.0372199 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0370632 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0365365 |
| FRMD5 | FERM domain containing 5 | 0.0348903 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0347463 |
| LAMB3 | laminin, beta 3 | 0.0346999 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0342171 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0331593 |
| CANX | calnexin | 0.0330847 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.030555 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0305397 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0302577 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0298735 |
| RPS12 | ribosomal protein S12 | 0.0294786 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0293322 |
| EREG | epiregulin | 0.0292088 |
| EPCAM | epithelial cell adhesion molecule | 0.0289599 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.028597 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0285625 |
| PTK2 | protein tyrosine kinase 2 | 0.0280462 |
| MKI67 | marker of proliferation Ki-67 | 0.0273941 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0273715 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 0.0272538 |
| CALR | calreticulin | 0.0267174 |
| AHNAK | AHNAK nucleoprotein | 0.0263594 |
| USP3 | ubiquitin specific peptidase 3 | 0.0261574 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0261187 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0256711 |
| RPL37A | ribosomal protein L37a | 0.0253836 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0253054 |
| RREB1 | ras responsive element binding protein 1 | 0.0251963 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0250927 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0250452 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.02501 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0249045 |
| ABHD17C | abhydrolase domain containing 17C | 0.0248542 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0246106 |
| FHIT | fragile histidine triad | 0.024246 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0240901 |
| MSI2 | musashi RNA-binding protein 2 | 0.0240864 |
| SET | SET nuclear proto-oncogene | 0.0240174 |
| ANO6 | anoctamin 6 | 0.0239125 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.023773 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0237532 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0234225 |
| RPS17 | ribosomal protein S17 | 0.0232965 |
| ANLN | anillin, actin binding protein | 0.0232786 |
| NFIA | nuclear factor I/A | 0.023132 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0230353 |
| NCKAP1 | NCK-associated protein 1 | 0.0227042 |
| TPR | translocated promoter region, nuclear basket protein | 0.0226426 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0223993 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0222659 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.02225 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0222253 |
| EXOC4 | exocyst complex component 4 | 0.0222207 |
| RPS18 | ribosomal protein S18 | 0.022211 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.021822 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0216123 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0215808 |
| AFDN | afadin, adherens junction formation factor | 0.0215741 |
| SLK | STE20-like kinase | 0.0213121 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0211311 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0211219 |
| STK39 | serine threonine kinase 39 | 0.0211038 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0210826 |
| WAC | WW domain containing adaptor with coiled-coil | 0.021081 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0210393 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0209808 |
| DSPP | dentin sialophosphoprotein | 0.0208954 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0208009 |
| CCNY | cyclin Y | 0.0207128 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0207088 |
| RPL7A | ribosomal protein L7a | 0.0206453 |
| NEK7 | NIMA-related kinase 7 | 0.0204941 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.17745 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.123452 |
| LMO7 | LIM domain 7 | -0.111714 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.102661 |
| FLNB | filamin B, beta | -0.0956716 |
| MYO1E | myosin IE | -0.0901588 |
| RPL35A | ribosomal protein L35a | -0.0899657 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0857992 |
| ACTG1 | actin gamma 1 | -0.0830803 |
| RPLP1 | ribosomal protein, large, P1 | -0.0785008 |
| EGR1 | early growth response 1 | -0.0742193 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0692099 |
| RPS6 | ribosomal protein S6 | -0.0679808 |
| VCL | vinculin | -0.0666073 |
| MYOF | myoferlin | -0.0657269 |
| CLDN4 | claudin 4 | -0.0655384 |
| TJP1 | tight junction protein 1 | -0.0636775 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0606391 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | -0.0602927 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0598643 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0596096 |
| RPS19 | ribosomal protein S19 | -0.0576373 |
| OXSR1 | oxidative stress responsive 1 | -0.0571159 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0565626 |
| TMSB10 | thymosin beta 10 | -0.0555142 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0539139 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0537839 |
| TXNRD1 | thioredoxin reductase 1 | -0.0515321 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0514112 |
| MX1 | MX dynamin-like GTPase 1 | -0.0505031 |
| PRSS3 | protease, serine, 3 | -0.0496459 |
| CALB1 | calbindin 1, 28kDa | -0.0480241 |
| RIGI | RNA sensor RIG-I | -0.0477787 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0439448 |
| ANXA2 | annexin A2 | -0.0437569 |
| PKP2 | plakophilin 2 | -0.0430924 |
| POTEF | POTE ankyrin domain family, member F | -0.0419509 |
| SQSTM1 | sequestosome 1 | -0.0415996 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0413628 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0403802 |
| RNF213 | ring finger protein 213 | -0.0403789 |
| MX2 | MX dynamin-like GTPase 2 | -0.0382025 |
| LAMA4 | laminin, alpha 4 | -0.0377734 |
| PLSCR1 | phospholipid scramblase 1 | -0.0372536 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0370828 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0368781 |
| GDF15 | growth differentiation factor 15 | -0.0366461 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0362736 |
| MT2A | metallothionein 2A | -0.0355055 |
| SP100 | SP100 nuclear antigen | -0.0350045 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0347941 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0332472 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0330144 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0325642 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0316122 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.03054 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.0301826 |
| DSG3 | desmoglein 3 | -0.0300663 |
| FHL2 | four and a half LIM domains 2 | -0.0297747 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0297015 |
| TRIM2 | tripartite motif containing 2 | -0.0295986 |
| RPLP0 | ribosomal protein, large, P0 | -0.0293501 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.029153 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0288893 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0287789 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0286742 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0284853 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0283527 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | -0.0274993 |
| HMGA1 | high mobility group AT-hook 1 | -0.0273787 |
| ATP10B | ATPase, class V, type 10B | -0.0272686 |
| AREG | amphiregulin | -0.0269213 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0268415 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0262576 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0262556 |
| ETNK1 | ethanolamine kinase 1 | -0.0259864 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0253752 |
| RPS20 | ribosomal protein S20 | -0.0253635 |
| TMEM45B | transmembrane protein 45B | -0.0253271 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0253149 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0252961 |
| NDRG1 | N-myc downstream regulated 1 | -0.0250595 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | -0.0250045 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0247295 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0244814 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0242908 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.024018 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0237674 |
| RPL34 | ribosomal protein L34 | -0.0235908 |
| AHCYL2 | adenosylhomocysteinase-like 2 | -0.0230321 |
| PLEKHG1 | pleckstrin homology domain containing, family G (with RhoGef domain) member 1 | -0.0228878 |
| UBAP2 | ubiquitin associated protein 2 | -0.0228177 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.022735 |
| PKM | pyruvate kinase, muscle | -0.0226323 |
| RPS14 | ribosomal protein S14 | -0.0225478 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0223266 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | -0.022159 |
| GOLGA4 | golgin A4 | -0.0220125 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.021919 |
| NLRP1 | NLR family, pyrin domain containing 1 | -0.0217969 |
