| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rimonabant (Hydrochloride) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rimonabant (Hydrochloride)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.171496 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.117377 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0976183 |
| TMSB4X | thymosin beta 4, X-linked | 0.0775893 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0603951 |
| FMNL2 | formin-like 2 | 0.0597719 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0576289 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0534344 |
| RPL37A | ribosomal protein L37a | 0.0514598 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0503027 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0499355 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0497873 |
| RPS12 | ribosomal protein S12 | 0.0480285 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0479643 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0472572 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.047077 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0469196 |
| SET | SET nuclear proto-oncogene | 0.0462145 |
| CAPRIN2 | caprin family member 2 | 0.0461413 |
| RPL3 | ribosomal protein L3 | 0.0456596 |
| CALR | calreticulin | 0.0435589 |
| OGA | O-GlcNAcase | 0.043453 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0421676 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0417978 |
| RNF145 | ring finger protein 145 | 0.0414965 |
| HDGF | hepatoma-derived growth factor | 0.0413638 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0408474 |
| RPS3 | ribosomal protein S3 | 0.0403937 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0392662 |
| RPS27A | ribosomal protein S27a | 0.0392211 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0390179 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0386263 |
| WDR43 | WD repeat domain 43 | 0.03747 |
| TPM3 | tropomyosin 3 | 0.0372031 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0368342 |
| XPO1 | exportin 1 | 0.0362806 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0359257 |
| MATR3 | matrin 3 | 0.0358 |
| RPL4 | ribosomal protein L4 | 0.0356973 |
| PCBP2 | poly(rC) binding protein 2 | 0.0354619 |
| VEGFA | vascular endothelial growth factor A | 0.0353713 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0345441 |
| RPL7A | ribosomal protein L7a | 0.0342979 |
| RASAL2 | RAS protein activator like 2 | 0.0339441 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0335505 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0335408 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0334327 |
| RPS6 | ribosomal protein S6 | 0.0334022 |
| TOP1 | topoisomerase (DNA) I | 0.0328611 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0322221 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0321552 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0319724 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0319564 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0318545 |
| RPS17 | ribosomal protein S17 | 0.0317104 |
| RBM25 | RNA binding motif protein 25 | 0.0317046 |
| RPL23 | ribosomal protein L23 | 0.031524 |
| RPL5 | ribosomal protein L5 | 0.0309363 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.030681 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0306546 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.030058 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0293953 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.0293432 |
| WAC | WW domain containing adaptor with coiled-coil | 0.029317 |
| ZNF292 | zinc finger protein 292 | 0.0292828 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0289574 |
| RPL7 | ribosomal protein L7 | 0.028942 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0287154 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0285953 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0285167 |
| FTL | ferritin, light polypeptide | 0.0284306 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0283801 |
| NUP58 | nucleoporin 58 | 0.0283718 |
| HELZ | helicase with zinc finger | 0.0279719 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0278774 |
| FBXO42 | F-box protein 42 | 0.0278697 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0277857 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0276943 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0276015 |
| RPS8 | ribosomal protein S8 | 0.0275821 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0275195 |
| RBM39 | RNA binding motif protein 39 | 0.0267836 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0267629 |
| RPL31 | ribosomal protein L31 | 0.0265896 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0264318 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0262683 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0261841 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0260968 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0256252 |
| RPS23 | ribosomal protein S23 | 0.025375 |
| MOK | MOK protein kinase | 0.0252659 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0252244 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0250412 |
| SETD5 | SET domain containing 5 | 0.0249798 |
| RPL37 | ribosomal protein L37 | 0.0249309 |
| MKI67 | marker of proliferation Ki-67 | 0.0246547 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0246051 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0245722 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0238752 |
| FAM13B | family with sequence similarity 13, member B | 0.0237797 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.266348 |
| TP63 | tumor protein p63 | -0.167726 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.152955 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.117238 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.114548 |
| LOC112694756 | uncharaterized LOC112694756 | -0.105856 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.104473 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0904464 |
| CD44 | CD44 molecule (Indian blood group) | -0.0887013 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0864737 |
| VIM | vimentin | -0.0840945 |
| RIGI | RNA sensor RIG-I | -0.070683 |
| EGR1 | early growth response 1 | -0.0700279 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0660172 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0605737 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0594605 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0567645 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0554764 |
| ACTG1 | actin gamma 1 | -0.0551292 |
| TXNRD1 | thioredoxin reductase 1 | -0.0549937 |
| EHBP1 | EH domain binding protein 1 | -0.0545348 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0538755 |
| RNF213 | ring finger protein 213 | -0.0528552 |
| CADM2 | cell adhesion molecule 2 | -0.0520916 |
| SP100 | SP100 nuclear antigen | -0.0501033 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0500657 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0497987 |
| HMGA1 | high mobility group AT-hook 1 | -0.0488058 |
| RUNX1 | runt-related transcription factor 1 | -0.0484166 |
| PLSCR1 | phospholipid scramblase 1 | -0.0471075 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0466085 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0452612 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0449425 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0446937 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0435301 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0415855 |
| PDE10A | phosphodiesterase 10A | -0.0386616 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0381491 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0380925 |
| HDAC9 | histone deacetylase 9 | -0.037521 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0361496 |
| HLA-B | major histocompatibility complex, class I, B | -0.0360076 |
| PMP22 | peripheral myelin protein 22 | -0.0355484 |
| KLF6 | Kruppel-like factor 6 | -0.0347238 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0337014 |
| EXOC4 | exocyst complex component 4 | -0.0328461 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0325013 |
| TMSB10 | thymosin beta 10 | -0.0323106 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0321374 |
| DST | dystonin | -0.0316503 |
| RPL35A | ribosomal protein L35a | -0.0309714 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0308507 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0303948 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0300659 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0298239 |
| OSMR | oncostatin M receptor | -0.0296934 |
| SQSTM1 | sequestosome 1 | -0.0294409 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0294331 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0293325 |
| LDHA | lactate dehydrogenase A | -0.0291067 |
| MT2A | metallothionein 2A | -0.0290242 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0288959 |
| AHNAK | AHNAK nucleoprotein | -0.0286692 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0285722 |
| TNS3 | tensin 3 | -0.0281286 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0278655 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0278251 |
| EMP1 | epithelial membrane protein 1 | -0.0266492 |
| TAPBP | TAP binding protein (tapasin) | -0.0262389 |
| PODXL | podocalyxin-like | -0.0258345 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0254366 |
| VCL | vinculin | -0.0254327 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0252367 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0251104 |
| DTX3L | deltex 3 like, E3 ubiquitin ligase | -0.0248008 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0246905 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -0.0242202 |
| SMYD3 | SET and MYND domain containing 3 | -0.0240926 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.023907 |
| JUN | jun proto-oncogene | -0.0238516 |
| NDRG1 | N-myc downstream regulated 1 | -0.023506 |
| FBXO11 | F-box protein 11 | -0.0233415 |
| ZNF644 | zinc finger protein 644 | -0.022929 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0229115 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0227747 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0227169 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0227078 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0226819 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0225626 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0225107 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.022509 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0224225 |
| DPH6 | diphthamine biosynthesis 6 | -0.0222893 |
| PYGL | phosphorylase, glycogen, liver | -0.0219832 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0219739 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0217765 |
| ZNF217 | zinc finger protein 217 | -0.021731 |
| DNER | delta/notch-like EGF repeat containing | -0.0215634 |
| PYGB | phosphorylase, glycogen; brain | -0.0214565 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0212989 |