| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rimonabant (Hydrochloride) perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rimonabant (Hydrochloride)_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.13799 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.110414 |
| PDE10A | phosphodiesterase 10A | 0.0766871 |
| SUCO | SUN domain containing ossification factor | 0.0716713 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0715452 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0706538 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0694943 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0684785 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.068075 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.067276 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0650518 |
| OGA | O-GlcNAcase | 0.0648381 |
| GOLGA4 | golgin A4 | 0.0644325 |
| PTMA | prothymosin, alpha | 0.0640107 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0636779 |
| SETD5 | SET domain containing 5 | 0.0628974 |
| HELZ | helicase with zinc finger | 0.061523 |
| HDLBP | high density lipoprotein binding protein | 0.0600601 |
| CANX | calnexin | 0.0590878 |
| CCNY | cyclin Y | 0.0577699 |
| WDR43 | WD repeat domain 43 | 0.0574997 |
| TFG | TRK-fused gene | 0.0566279 |
| ACTN4 | actinin, alpha 4 | 0.056392 |
| EGFR | epidermal growth factor receptor | 0.0562137 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0553044 |
| CERT1 | ceramide transporter 1 | 0.0542037 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0541196 |
| CTBP2 | C-terminal binding protein 2 | 0.0534686 |
| CSNK2A2 | casein kinase 2, alpha prime polypeptide | 0.0529578 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0519104 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0517851 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0514735 |
| RYBP | RING1 and YY1 binding protein | 0.0512491 |
| VEGFA | vascular endothelial growth factor A | 0.0503943 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0500019 |
| GLG1 | golgi glycoprotein 1 | 0.0496165 |
| MED13 | mediator complex subunit 13 | 0.0493855 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0492142 |
| USP3 | ubiquitin specific peptidase 3 | 0.0490981 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0486996 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.0486356 |
| ATP11A | ATPase, class VI, type 11A | 0.0486158 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.048517 |
| DEK | DEK proto-oncogene | 0.0484862 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0479649 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0478683 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0477442 |
| NBEAL1 | neurobeachin-like 1 | 0.047592 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.047236 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | 0.046542 |
| RPL4 | ribosomal protein L4 | 0.0463588 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0462645 |
| SET | SET nuclear proto-oncogene | 0.0458934 |
| DSTN | destrin (actin depolymerizing factor) | 0.0455285 |
| PTK2 | protein tyrosine kinase 2 | 0.044728 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0445174 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0444744 |
| SBF2 | SET binding factor 2 | 0.0438442 |
| MAP4 | microtubule-associated protein 4 | 0.0436921 |
| ZNF148 | zinc finger protein 148 | 0.0431308 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0427086 |
| PKN2 | protein kinase N2 | 0.0422963 |
| FAM168A | family with sequence similarity 168, member A | 0.04221 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.042096 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0418007 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 0.0414084 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0409851 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0409793 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0407685 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.0407634 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0406817 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.040549 |
| BBX | bobby sox homolog (Drosophila) | 0.0400837 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0396323 |
| NCKAP1 | NCK-associated protein 1 | 0.0396119 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0393742 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0392945 |
| XPO1 | exportin 1 | 0.039268 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0391068 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0389991 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0389845 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0384675 |
| APP | amyloid beta (A4) precursor protein | 0.0381872 |
| TMEM65 | transmembrane protein 65 | 0.0379278 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0377101 |
| OLA1 | Obg-like ATPase 1 | 0.0376323 |
| STK24 | serine/threonine kinase 24 | 0.0367239 |
| COPA | coatomer protein complex, subunit alpha | 0.0366661 |
| HDAC8 | histone deacetylase 8 | 0.0363774 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0363035 |
| PDS5A | PDS5 cohesin associated factor A | 0.0361757 |
| WDR45B | WD repeat domain 45B | 0.035837 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0357773 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0355645 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0355642 |
| NDRG1 | N-myc downstream regulated 1 | 0.0354547 |
| AFF1 | AF4/FMR2 family, member 1 | 0.035261 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0351866 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0350993 |
| NBAS | neuroblastoma amplified sequence | 0.0350223 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.165386 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.150446 |
| S100A9 | S100 calcium binding protein A9 | -0.149294 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.146977 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.118419 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.113044 |
| LMO7 | LIM domain 7 | -0.110025 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.107471 |
| FN1 | fibronectin 1 | -0.104356 |
| MUC16 | mucin 16, cell surface associated | -0.0977746 |
| TMSB10 | thymosin beta 10 | -0.0975956 |
| ASPH | aspartate beta-hydroxylase | -0.0930539 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0885326 |
| EFNA5 | ephrin-A5 | -0.0876158 |
| ABHD17C | abhydrolase domain containing 17C | -0.0838199 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0807386 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0793472 |
| TPM4 | tropomyosin 4 | -0.0748344 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.074798 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0725065 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0710512 |
| FTL | ferritin, light polypeptide | -0.0702038 |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | -0.0701337 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0680492 |
| VIM | vimentin | -0.0670169 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0662492 |
| PRKCSH | protein kinase C substrate 80K-H | -0.0638512 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0621494 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0618561 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0616402 |
| PRKCA | protein kinase C, alpha | -0.0606535 |
| RAB10 | RAB10, member RAS oncogene family | -0.0595903 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0594564 |
| ATOSA | atos homolog A | -0.0594342 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0574061 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0569766 |
| RBM47 | RNA binding motif protein 47 | -0.0564905 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0563201 |
| RNF213 | ring finger protein 213 | -0.0553947 |
| THBS1 | thrombospondin 1 | -0.0549615 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0548757 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0547936 |
| RPLP0 | ribosomal protein, large, P0 | -0.0546156 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.054427 |
| JMJD1C | jumonji domain containing 1C | -0.0540723 |
| RPS25 | ribosomal protein S25 | -0.0537414 |
| KATNBL1 | katanin p80 subunit B-like 1 | -0.0531857 |
| LAMC2 | laminin, gamma 2 | -0.052964 |
| RAI14 | retinoic acid induced 14 | -0.051877 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0517996 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0515528 |
| S100A6 | S100 calcium binding protein A6 | -0.051261 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0504379 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0502233 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0495995 |
| KYNU | kynureninase | -0.0491617 |
| MAPK6 | mitogen-activated protein kinase 6 | -0.047504 |
| RPL35A | ribosomal protein L35a | -0.0468846 |
| NABP1 | nucleic acid binding protein 1 | -0.0467339 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0464588 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0444641 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0444103 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0442538 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0442308 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0439355 |
| RPS14 | ribosomal protein S14 | -0.0437098 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0430781 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0420376 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0417582 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0417257 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0417229 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0415225 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0412513 |
| GNAS | GNAS complex locus | -0.0409055 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0406643 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0402938 |
| SEPTIN10 | septin 10 | -0.040277 |
| TRIM33 | tripartite motif containing 33 | -0.0402496 |
| RHOA | ras homolog family member A | -0.0401738 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0401175 |
| STC1 | stanniocalcin 1 | -0.040104 |
| RPS24 | ribosomal protein S24 | -0.0400601 |
| RPS8 | ribosomal protein S8 | -0.0399136 |
| HLA-B | major histocompatibility complex, class I, B | -0.0397234 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.039716 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0395056 |
| EGR1 | early growth response 1 | -0.039227 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0390444 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0389665 |
| EXOC6B | exocyst complex component 6B | -0.0387282 |
| RCOR1 | REST corepressor 1 | -0.0383201 |
| RPS16 | ribosomal protein S16 | -0.0382714 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0379473 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0376328 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0372728 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0366549 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0363471 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0357267 |
| SNX14 | sorting nexin 14 | -0.0353483 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0349234 |
