| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rimonabant (Hydrochloride) perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rimonabant (Hydrochloride)_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GRAMD1B | GRAM domain containing 1B | 0.132989 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0857179 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0730806 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0729687 |
| TXNRD1 | thioredoxin reductase 1 | 0.0630499 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0630484 |
| OGA | O-GlcNAcase | 0.0624019 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0484557 |
| RRM2 | ribonucleotide reductase M2 | 0.0440543 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0433728 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0432268 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0429384 |
| PTMA | prothymosin, alpha | 0.0422281 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0405437 |
| XPO1 | exportin 1 | 0.0389196 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.038164 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0370797 |
| TPM3 | tropomyosin 3 | 0.0367243 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0361115 |
| SET | SET nuclear proto-oncogene | 0.0354643 |
| CEP192 | centrosomal protein 192kDa | 0.034588 |
| MKI67 | marker of proliferation Ki-67 | 0.0339261 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0338133 |
| RPL37 | ribosomal protein L37 | 0.033593 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.0321284 |
| RTN4 | reticulon 4 | 0.0318532 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0318233 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0315574 |
| ZNF292 | zinc finger protein 292 | 0.0313906 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.030492 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0298756 |
| RPL4 | ribosomal protein L4 | 0.029785 |
| AHNAK | AHNAK nucleoprotein | 0.0294045 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0293659 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0287898 |
| CTTN | cortactin | 0.0287623 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0283956 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0281911 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0279506 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0277608 |
| CPSF6 | cleavage and polyadenylation specific factor 6, 68kDa | 0.027573 |
| SMAD3 | SMAD family member 3 | 0.0271159 |
| EXOC4 | exocyst complex component 4 | 0.0266225 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0265477 |
| MED13L | mediator complex subunit 13-like | 0.0263766 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0262705 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0255624 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.0255352 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0248306 |
| KCMF1 | potassium channel modulatory factor 1 | 0.024536 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.024337 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0243214 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0242195 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0241293 |
| APP | amyloid beta (A4) precursor protein | 0.0238969 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0238931 |
| CEP250 | centrosomal protein 250kDa | 0.0237111 |
| ANKRD36B | ankyrin repeat domain 36B | 0.0233044 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.0232848 |
| TLK1 | tousled-like kinase 1 | 0.0232822 |
| PLCB4 | phospholipase C, beta 4 | 0.0232055 |
| ZFR | zinc finger RNA binding protein | 0.0231865 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0228052 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | 0.0227388 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0227311 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0227175 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0226114 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0225713 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.0225649 |
| RNF145 | ring finger protein 145 | 0.0225028 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0223461 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0223217 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0223096 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0221387 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0219894 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0219007 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0218338 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0217541 |
| SRPK2 | SRSF protein kinase 2 | 0.0217008 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0214466 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.021378 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0213515 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.021331 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0212469 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 | 0.0212305 |
| MELK | maternal embryonic leucine zipper kinase | 0.021181 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | 0.0211198 |
| TMEM41B | transmembrane protein 41B | 0.0209419 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0208742 |
| TNPO1 | transportin 1 | 0.0206859 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0205398 |
| PALS1 | protein associated with LIN7 1, MAGUK p55 family member | 0.020504 |
| RAD51B | RAD51 paralog B | 0.0201967 |
| ANO6 | anoctamin 6 | 0.0201303 |
| STX16 | syntaxin 16 | 0.0201192 |
| RNF169 | ring finger protein 169 | 0.019996 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0199908 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0196751 |
| PNN | pinin, desmosome associated protein | 0.0195173 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | 0.0193491 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.453588 |
| EGR1 | early growth response 1 | -0.19566 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0792777 |
| TMSB10 | thymosin beta 10 | -0.0774021 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0766705 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0764336 |
| POTEF | POTE ankyrin domain family, member F | -0.0762568 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0716632 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0676673 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0670355 |
| VIM | vimentin | -0.0667227 |
| MCL1 | myeloid cell leukemia 1 | -0.0654176 |
| COPA | coatomer protein complex, subunit alpha | -0.0551445 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0513952 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0489281 |
| BRD2 | bromodomain containing 2 | -0.0478875 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0460951 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.045141 |
| PFN1 | profilin 1 | -0.044794 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0434362 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0391982 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0385069 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0384543 |
| RPL35A | ribosomal protein L35a | -0.038306 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.038149 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0378945 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0374638 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0367039 |
| NABP1 | nucleic acid binding protein 1 | -0.0362133 |
| INTS6 | integrator complex subunit 6 | -0.0360239 |
| TAPBP | TAP binding protein (tapasin) | -0.0352379 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0347937 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0344519 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0341965 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0338423 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0331789 |
| OSMR | oncostatin M receptor | -0.0326023 |
| FTL | ferritin, light polypeptide | -0.0325861 |
| HMGA1 | high mobility group AT-hook 1 | -0.0320672 |
| VCL | vinculin | -0.0319836 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0315132 |
| YBX1 | Y box binding protein 1 | -0.0305318 |
| TPM4 | tropomyosin 4 | -0.0303414 |
| ZNF207 | zinc finger protein 207 | -0.0302579 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0301054 |
| ATXN1 | ataxin 1 | -0.0299304 |
| GNAS | GNAS complex locus | -0.0294581 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0291532 |
| STC1 | stanniocalcin 1 | -0.0289452 |
| ACTG1 | actin gamma 1 | -0.0288749 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0286216 |
| TLN1 | talin 1 | -0.0284933 |
| GPATCH2L | G patch domain containing 2-like | -0.0280533 |
| RPS19 | ribosomal protein S19 | -0.0272472 |
| BPTF | bromodomain PHD finger transcription factor | -0.027214 |
| MORF4L2 | mortality factor 4 like 2 | -0.0268556 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0265227 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0261373 |
| GOLGB1 | golgin B1 | -0.0260841 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.02577 |
| RPLP1 | ribosomal protein, large, P1 | -0.0256953 |
| TPM2 | tropomyosin 2 (beta) | -0.0255895 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0255395 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0254289 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0251031 |
| TPI1 | triosephosphate isomerase 1 | -0.0248379 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0247798 |
| ARF4 | ADP-ribosylation factor 4 | -0.0247693 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0246715 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0243057 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0243056 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0241039 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0235105 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0234939 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0229868 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0229051 |
| BSG | basigin (Ok blood group) | -0.0226229 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0226032 |
| VMP1 | vacuole membrane protein 1 | -0.0218588 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.021821 |
| RSF1 | remodeling and spacing factor 1 | -0.0217786 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0217731 |
| RYR3 | ryanodine receptor 3 | -0.0216817 |
| RPLP0 | ribosomal protein, large, P0 | -0.0214741 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0214567 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0213284 |
| NDRG1 | N-myc downstream regulated 1 | -0.0212303 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0211264 |
| BRD4 | bromodomain containing 4 | -0.02107 |
| RPS6 | ribosomal protein S6 | -0.0209859 |
| IGF2 | insulin-like growth factor 2 | -0.0209849 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0208631 |
| MYADM | myeloid-associated differentiation marker | -0.0208018 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0207973 |
| HLA-B | major histocompatibility complex, class I, B | -0.0206679 |
| JUN | jun proto-oncogene | -0.0204616 |
| TAGLN2 | transgelin 2 | -0.0202713 |
| MEF2D | myocyte enhancer factor 2D | -0.0198156 |
| SETX | senataxin | -0.0198073 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0196014 |
