| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rimonabant (Hydrochloride) perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rimonabant (Hydrochloride)_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.158835 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.132998 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.130225 |
| VEGFA | vascular endothelial growth factor A | 0.129994 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.119664 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.113211 |
| POTEF | POTE ankyrin domain family, member F | 0.0970212 |
| ASPH | aspartate beta-hydroxylase | 0.0771375 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0734616 |
| TPM3 | tropomyosin 3 | 0.0710977 |
| CALR | calreticulin | 0.0710884 |
| TMSB4X | thymosin beta 4, X-linked | 0.0700714 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0676457 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0674234 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0606891 |
| HSPA8 | heat shock 70kDa protein 8 | 0.060098 |
| HDGF | hepatoma-derived growth factor | 0.0598424 |
| PTMA | prothymosin, alpha | 0.0596028 |
| RNF145 | ring finger protein 145 | 0.0592363 |
| MSN | moesin | 0.0583064 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0576297 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0574715 |
| KRT18 | keratin 18, type I | 0.0562741 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0548805 |
| UBC | ubiquitin C | 0.0545802 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.053353 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0532184 |
| NAV2 | neuron navigator 2 | 0.052423 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0523212 |
| ARRDC3 | arrestin domain containing 3 | 0.0510977 |
| PCBP2 | poly(rC) binding protein 2 | 0.0507946 |
| RPL4 | ribosomal protein L4 | 0.0505981 |
| RPS3 | ribosomal protein S3 | 0.0505965 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.04766 |
| RPS12 | ribosomal protein S12 | 0.0473551 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0468751 |
| RHOA | ras homolog family member A | 0.0467743 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0461197 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0441279 |
| SET | SET nuclear proto-oncogene | 0.0440879 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0436532 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0432516 |
| RPL3 | ribosomal protein L3 | 0.042961 |
| HMGB2 | high mobility group box 2 | 0.0426305 |
| ENO1 | enolase 1, (alpha) | 0.0421914 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0411141 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0400865 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0388767 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0383307 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0370775 |
| AHNAK | AHNAK nucleoprotein | 0.0365188 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0356731 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0349605 |
| RPL7 | ribosomal protein L7 | 0.0346177 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0343169 |
| LDHA | lactate dehydrogenase A | 0.0340572 |
| PKM | pyruvate kinase, muscle | 0.0338009 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0336584 |
| KRT7 | keratin 7, type II | 0.0336203 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.033068 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0329322 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0323644 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.032342 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0322704 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0322144 |
| DSPP | dentin sialophosphoprotein | 0.032073 |
| LAMC2 | laminin, gamma 2 | 0.0319998 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0319637 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0316323 |
| PLEC | plectin | 0.0311134 |
| PTK2 | protein tyrosine kinase 2 | 0.0309609 |
| RPL5 | ribosomal protein L5 | 0.030721 |
| GRB10 | growth factor receptor-bound protein 10 | 0.029943 |
| FAM13A | family with sequence similarity 13, member A | 0.0298377 |
| PAPOLA | poly(A) polymerase alpha | 0.0295566 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0290346 |
| MATR3 | matrin 3 | 0.0287486 |
| RPS17 | ribosomal protein S17 | 0.0286655 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0284999 |
| NUP58 | nucleoporin 58 | 0.0283824 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0278836 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0276454 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0275057 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0271431 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0271413 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0269928 |
| CCNL1 | cyclin L1 | 0.0267288 |
| IRF6 | interferon regulatory factor 6 | 0.0260555 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0259342 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0258612 |
| RPL14 | ribosomal protein L14 | 0.0252629 |
| PLAU | plasminogen activator, urokinase | 0.0248315 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0247974 |
| DSTN | destrin (actin depolymerizing factor) | 0.0246497 |
| RACK1 | receptor for activated C kinase 1 | 0.0246446 |
| HMGB3 | high mobility group box 3 | 0.0242759 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0242722 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.02423 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0242099 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.023942 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.215933 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.19375 |
| FTL | ferritin, light polypeptide | -0.127152 |
| FN1 | fibronectin 1 | -0.0965284 |
| RPL35A | ribosomal protein L35a | -0.0934326 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0760856 |
| TMSB10 | thymosin beta 10 | -0.0713731 |
| ACTG1 | actin gamma 1 | -0.0681753 |
| LMO7 | LIM domain 7 | -0.0565467 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0551114 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0545668 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0538888 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0532587 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0514113 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0489443 |
| RPL34 | ribosomal protein L34 | -0.0484468 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0460921 |
| CD2AP | CD2-associated protein | -0.0456791 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0432737 |
| ARF1 | ADP-ribosylation factor 1 | -0.04158 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0410828 |
| TMEM263 | transmembrane protein 263 | -0.0408921 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0397822 |
| GNAS | GNAS complex locus | -0.0394571 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.038471 |
| S100A6 | S100 calcium binding protein A6 | -0.0375224 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0364937 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0364356 |
| EGR1 | early growth response 1 | -0.0362023 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0356253 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0355721 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0347159 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0347046 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.033971 |
| MYO1E | myosin IE | -0.0335618 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0318362 |
| EXT1 | exostosin glycosyltransferase 1 | -0.031588 |
| ERBIN | erbb2 interacting protein | -0.0315411 |
| OCLN | occludin | -0.0309181 |
| KLHL24 | kelch-like family member 24 | -0.0303967 |
| PALLD | palladin, cytoskeletal associated protein | -0.0299915 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0293323 |
| JMJD1C | jumonji domain containing 1C | -0.0285813 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0283934 |
| HMGA1 | high mobility group AT-hook 1 | -0.0282685 |
| TXNIP | thioredoxin interacting protein | -0.0280232 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0278783 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0277503 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.0274659 |
| FNIP1 | folliculin interacting protein 1 | -0.0267494 |
| FBXO11 | F-box protein 11 | -0.0264773 |
| H1-0 | H1.0 linker histone | -0.0261995 |
| ANKRD17 | ankyrin repeat domain 17 | -0.026041 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0258115 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0256249 |
| S100A10 | S100 calcium binding protein A10 | -0.0255782 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0255072 |
| IL6ST | interleukin 6 signal transducer | -0.0254967 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0253786 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0252108 |
| FBXO34 | F-box protein 34 | -0.0245292 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0245266 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0245059 |
| NEK7 | NIMA-related kinase 7 | -0.0244528 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0244074 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0243174 |
| VGLL3 | vestigial-like family member 3 | -0.0243054 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0240019 |
| NDRG1 | N-myc downstream regulated 1 | -0.0239658 |
| TJP1 | tight junction protein 1 | -0.0237155 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0235849 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0234201 |
| RPLP1 | ribosomal protein, large, P1 | -0.0233316 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0233091 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0232147 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0229858 |
| UBAP1 | ubiquitin associated protein 1 | -0.0229085 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | -0.0227695 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 | -0.0224065 |
| TMEM123 | transmembrane protein 123 | -0.0222866 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0220624 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha | -0.0220136 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0219038 |
| ARHGAP20 | Rho GTPase activating protein 20 | -0.0217317 |
| SH3RF1 | SH3 domain containing ring finger 1 | -0.0216238 |
| CEP95 | centrosomal protein 95kDa | -0.0215017 |
| EFNA5 | ephrin-A5 | -0.0214894 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0213057 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0212617 |
| SMIM14 | small integral membrane protein 14 | -0.0212157 |
| NF1 | neurofibromin 1 | -0.0210485 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0208842 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0208088 |
| ATOSA | atos homolog A | -0.0208022 |
| USP53 | ubiquitin specific peptidase 53 | -0.0206459 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0204875 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0201947 |
| INPP5F | inositol polyphosphate-5-phosphatase F | -0.0200441 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0199981 |
| OSMR | oncostatin M receptor | -0.0198778 |
