| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rimonabant (Hydrochloride) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rimonabant (Hydrochloride)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.192674 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.176948 |
| THBS1 | thrombospondin 1 | 0.141974 |
| TMSB4X | thymosin beta 4, X-linked | 0.136565 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.101279 |
| COL11A1 | collagen, type XI, alpha 1 | 0.100563 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0954698 |
| VIM | vimentin | 0.0902476 |
| CALR | calreticulin | 0.0831549 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0804213 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.078103 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0744277 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0675812 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0600424 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0596329 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0589695 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.0558096 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0546722 |
| RPS12 | ribosomal protein S12 | 0.0546048 |
| AHNAK | AHNAK nucleoprotein | 0.0542205 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.053146 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0522626 |
| SET | SET nuclear proto-oncogene | 0.0520683 |
| RPS8 | ribosomal protein S8 | 0.0520499 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0518709 |
| COL3A1 | collagen, type III, alpha 1 | 0.0515747 |
| MATR3 | matrin 3 | 0.0509989 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0490827 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0484687 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0480817 |
| RPS3 | ribosomal protein S3 | 0.0477942 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0466792 |
| ITGAV | integrin, alpha V | 0.0434567 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0433157 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0421828 |
| RPL4 | ribosomal protein L4 | 0.0417653 |
| RAI1 | retinoic acid induced 1 | 0.0416916 |
| FBL | fibrillarin | 0.0415415 |
| MKI67 | marker of proliferation Ki-67 | 0.0404004 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0399843 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0398251 |
| RPS21 | ribosomal protein S21 | 0.0397522 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0387751 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0385449 |
| RPS27A | ribosomal protein S27a | 0.0385354 |
| CALU | calumenin | 0.0378272 |
| RPL19 | ribosomal protein L19 | 0.0377288 |
| MYO10 | myosin X | 0.0376731 |
| RPL23 | ribosomal protein L23 | 0.0373129 |
| GPHN | gephyrin | 0.0371182 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0371051 |
| FST | follistatin | 0.0369882 |
| TPM3 | tropomyosin 3 | 0.0368987 |
| RPL7 | ribosomal protein L7 | 0.0367263 |
| CAVIN1 | caveolae associated protein 1 | 0.0366836 |
| EMP1 | epithelial membrane protein 1 | 0.0364664 |
| RPL12 | ribosomal protein L12 | 0.0363058 |
| RHEB | Ras homolog enriched in brain | 0.0361606 |
| OGA | O-GlcNAcase | 0.0361478 |
| ANXA1 | annexin A1 | 0.0356179 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.0354621 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0354585 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0352982 |
| RPL37 | ribosomal protein L37 | 0.0348349 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0348308 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0348057 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0343758 |
| HMGB2 | high mobility group box 2 | 0.0341989 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.034041 |
| BBX | bobby sox homolog (Drosophila) | 0.0335988 |
| TPR | translocated promoter region, nuclear basket protein | 0.0334229 |
| CANX | calnexin | 0.033337 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0331248 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.032926 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0329062 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0328892 |
| GPC6 | glypican 6 | 0.0326308 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0324749 |
| RPLP2 | ribosomal protein, large, P2 | 0.0323327 |
| LDHA | lactate dehydrogenase A | 0.0322376 |
| CENPF | centromere protein F, 350/400kDa | 0.0320809 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0318351 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0318242 |
| USP53 | ubiquitin specific peptidase 53 | 0.0314366 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0309552 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0301991 |
| STMN1 | stathmin 1 | 0.0299819 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.02993 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0298021 |
| IPO7 | importin 7 | 0.029761 |
| RPS6 | ribosomal protein S6 | 0.0296437 |
| PGK1 | phosphoglycerate kinase 1 | 0.0293865 |
| H1-4 | H1.4 linker histone, cluster member | 0.0289708 |
| PDCD5 | programmed cell death 5 | 0.0289402 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0289323 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0286337 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.0285241 |
| RPLP1 | ribosomal protein, large, P1 | 0.0283962 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0283514 |
| RPS16 | ribosomal protein S16 | 0.0281511 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0968875 |
| SPAG9 | sperm associated antigen 9 | -0.0861299 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0658177 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0640098 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0634974 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0629379 |
| SYT1 | synaptotagmin I | -0.0559096 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0550123 |
| FBXO11 | F-box protein 11 | -0.0545982 |
| SRP54 | signal recognition particle 54kDa | -0.0497665 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0438959 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0429267 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.041183 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0396867 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.038534 |
| MAP4 | microtubule-associated protein 4 | -0.0379853 |
| NUP58 | nucleoporin 58 | -0.0363633 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0361734 |
| POTEF | POTE ankyrin domain family, member F | -0.0360455 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0352783 |
| JMJD1C | jumonji domain containing 1C | -0.0351029 |
| HDAC9 | histone deacetylase 9 | -0.0347578 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0335181 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0334195 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0332383 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0327342 |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | -0.031755 |
| UBXN7 | UBX domain protein 7 | -0.0310892 |
| COG6 | component of oligomeric golgi complex 6 | -0.0310609 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0308203 |
| LRRN3 | leucine rich repeat neuronal 3 | -0.0307582 |
| NRG1 | neuregulin 1 | -0.0306079 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0302953 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.030045 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0299193 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0297623 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0297071 |
| UBN2 | ubinuclein 2 | -0.0282248 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0279896 |
| SMYD3 | SET and MYND domain containing 3 | -0.0273918 |
| FGF13 | fibroblast growth factor 13 | -0.0273916 |
| PFN1 | profilin 1 | -0.0272439 |
| EPHA5 | EPH receptor A5 | -0.0267329 |
| RIGI | RNA sensor RIG-I | -0.0265613 |
| B2M | beta-2-microglobulin | -0.0264941 |
| GPC4 | glypican 4 | -0.0264624 |
| ZNF292 | zinc finger protein 292 | -0.0261843 |
| LATS2 | large tumor suppressor kinase 2 | -0.0261777 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0260354 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0257029 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0250972 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0249003 |
| ECT2 | epithelial cell transforming 2 | -0.024843 |
| NBEAL1 | neurobeachin-like 1 | -0.0248398 |
| WDR26 | WD repeat domain 26 | -0.0248267 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0243461 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | -0.0241692 |
| PKN2 | protein kinase N2 | -0.0240775 |
| PALS1 | protein associated with LIN7 1, MAGUK p55 family member | -0.0239049 |
| TGFB2 | transforming growth factor, beta 2 | -0.0238255 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | -0.0235992 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | -0.0234478 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.023379 |
| SASS6 | spindle assembly 6 homolog (C. elegans) | -0.0233291 |
| SCFD1 | sec1 family domain containing 1 | -0.0232698 |
| FOXK1 | forkhead box K1 | -0.0231002 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | -0.0230018 |
| PGPEP1L | pyroglutamyl-peptidase I-like | -0.0225828 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0223629 |
| PDS5B | PDS5 cohesin associated factor B | -0.0223259 |
| MAP2K4 | mitogen-activated protein kinase kinase 4 | -0.0223172 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 | -0.0222792 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0222211 |
| NFX1 | nuclear transcription factor, X-box binding 1 | -0.0221185 |
| RTN3 | reticulon 3 | -0.0220073 |
| CDH19 | cadherin 19, type 2 | -0.0219908 |
| RBM33 | RNA binding motif protein 33 | -0.021929 |
| PARD3 | par-3 family cell polarity regulator | -0.0217811 |
| NCOA1 | nuclear receptor coactivator 1 | -0.0217655 |
| DAG1 | dystroglycan 1 (dystrophin-associated glycoprotein 1) | -0.0216205 |
| CEP170 | centrosomal protein 170kDa | -0.0215219 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.0214175 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0213754 |
| CDH8 | cadherin 8, type 2 | -0.0213499 |
| E2F3 | E2F transcription factor 3 | -0.0211789 |
| CDK6 | cyclin-dependent kinase 6 | -0.02103 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0209498 |
| TAPBP | TAP binding protein (tapasin) | -0.02085 |
| MECP2 | methyl CpG binding protein 2 | -0.0206069 |
| SVIL | supervillin | -0.0204114 |
| OSBPL9 | oxysterol binding protein-like 9 | -0.0203456 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0203061 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0200227 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 | -0.0200061 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0199972 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | -0.019997 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0199214 |
| WDR43 | WD repeat domain 43 | -0.0199141 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | -0.0198374 |
| TXNRD1 | thioredoxin reductase 1 | -0.0198051 |
