| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rimonabant (Hydrochloride) perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rimonabant (Hydrochloride)_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0820405 |
| ACTG1 | actin gamma 1 | 0.0778915 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0677649 |
| OGA | O-GlcNAcase | 0.0578517 |
| NUP58 | nucleoporin 58 | 0.0558792 |
| LAMB3 | laminin, beta 3 | 0.054695 |
| USP3 | ubiquitin specific peptidase 3 | 0.0537391 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0528401 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0525768 |
| RLF | rearranged L-myc fusion | 0.0505656 |
| ZNF292 | zinc finger protein 292 | 0.0494861 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0494487 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0477553 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0467439 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.045573 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0442987 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0436378 |
| TXNRD1 | thioredoxin reductase 1 | 0.0429982 |
| TPD52 | tumor protein D52 | 0.0427569 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0420325 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0414516 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0403024 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0380106 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0377933 |
| ATP13A3 | ATPase type 13A3 | 0.0374968 |
| RASA2 | RAS p21 protein activator 2 | 0.0354788 |
| NCKAP1 | NCK-associated protein 1 | 0.0349261 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0342491 |
| FOXO3 | forkhead box O3 | 0.0338555 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0335274 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0332126 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0330934 |
| SPAG9 | sperm associated antigen 9 | 0.0327925 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0316675 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0316193 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0311252 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0308297 |
| CDK17 | cyclin-dependent kinase 17 | 0.0304856 |
| SNX9 | sorting nexin 9 | 0.0303262 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0302766 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0297228 |
| RNF145 | ring finger protein 145 | 0.0296227 |
| RBM39 | RNA binding motif protein 39 | 0.0295943 |
| GOLGA4 | golgin A4 | 0.0292457 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0288845 |
| STC1 | stanniocalcin 1 | 0.0288277 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0287802 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0281434 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0276894 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0276295 |
| YEATS2 | YEATS domain containing 2 | 0.0275741 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0272785 |
| WAC | WW domain containing adaptor with coiled-coil | 0.027137 |
| WDR45B | WD repeat domain 45B | 0.0271363 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0269337 |
| SET | SET nuclear proto-oncogene | 0.0269277 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0268109 |
| SBF2 | SET binding factor 2 | 0.0266255 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0265958 |
| PUM2 | pumilio RNA-binding family member 2 | 0.026585 |
| RBM33 | RNA binding motif protein 33 | 0.0264579 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0262267 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0259958 |
| SEPTIN7 | septin 7 | 0.0259826 |
| YTHDC1 | YTH domain containing 1 | 0.025899 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0257308 |
| RTN4 | reticulon 4 | 0.025686 |
| NEK7 | NIMA-related kinase 7 | 0.0255464 |
| FOXJ3 | forkhead box J3 | 0.0252479 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0252109 |
| ANXA5 | annexin A5 | 0.0251381 |
| SRPK2 | SRSF protein kinase 2 | 0.0248231 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0246741 |
| NAA35 | N(alpha)-acetyltransferase 35, NatC auxiliary subunit | 0.0245334 |
| MTF2 | metal response element binding transcription factor 2 | 0.0244104 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0243578 |
| PTK2 | protein tyrosine kinase 2 | 0.0240246 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0237628 |
| PHIP | pleckstrin homology domain interacting protein | 0.0237539 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0236231 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0235939 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0235196 |
| HELZ | helicase with zinc finger | 0.0234124 |
| LRRC8C | leucine rich repeat containing 8 family, member C | 0.023391 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.023355 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0233322 |
| RAB18 | RAB18, member RAS oncogene family | 0.0232374 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0231934 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0231213 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0230595 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0228156 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.022696 |
| WDR43 | WD repeat domain 43 | 0.0226811 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0225869 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0221737 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.022163 |
| TPR | translocated promoter region, nuclear basket protein | 0.0220795 |
| ECT2 | epithelial cell transforming 2 | 0.0219981 |
| XPO1 | exportin 1 | 0.0219607 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0218635 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.224047 |
| ZNF438 | zinc finger protein 438 | -0.168612 |
| FRMD6 | FERM domain containing 6 | -0.168186 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.145083 |
| MT2A | metallothionein 2A | -0.132478 |
| HMGA2 | high mobility group AT-hook 2 | -0.112791 |
| HDAC9 | histone deacetylase 9 | -0.108871 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.104749 |
| NAV3 | neuron navigator 3 | -0.102118 |
| NABP1 | nucleic acid binding protein 1 | -0.0945769 |
| FRMD4A | FERM domain containing 4A | -0.078107 |
| SP100 | SP100 nuclear antigen | -0.0749963 |
| RPS6 | ribosomal protein S6 | -0.0737424 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0723522 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0714305 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0668672 |
| BNC2 | basonuclin 2 | -0.0654305 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0652154 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0641471 |
| TMSB10 | thymosin beta 10 | -0.0625581 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0581229 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0571219 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0565742 |
| RPL35A | ribosomal protein L35a | -0.0562462 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0561119 |
| FLNB | filamin B, beta | -0.0559909 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.053047 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0523975 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0518111 |
| INTS6 | integrator complex subunit 6 | -0.0513923 |
| FTL | ferritin, light polypeptide | -0.0476276 |
| RAD51B | RAD51 paralog B | -0.0469587 |
| TTR | transthyretin | -0.0465943 |
| PCNX4 | pecanex 4 | -0.0464191 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0438807 |
| EGR1 | early growth response 1 | -0.0438545 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0437388 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0436955 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0426749 |
| RPLP1 | ribosomal protein, large, P1 | -0.0421477 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0420932 |
| NAV2 | neuron navigator 2 | -0.0409725 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.040449 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0402767 |
| FHIT | fragile histidine triad | -0.0401328 |
| MTAP | methylthioadenosine phosphorylase | -0.039441 |
| RPS8 | ribosomal protein S8 | -0.0388195 |
| RPS19 | ribosomal protein S19 | -0.038719 |
| EFNB2 | ephrin-B2 | -0.0383174 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.037378 |
| RPL31 | ribosomal protein L31 | -0.037145 |
| HMGA1 | high mobility group AT-hook 1 | -0.0364461 |
| RPS24 | ribosomal protein S24 | -0.0362564 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0361784 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0360671 |
| RPL12 | ribosomal protein L12 | -0.0360581 |
| CAST | calpastatin | -0.0351407 |
| RIGI | RNA sensor RIG-I | -0.0351236 |
| DGKI | diacylglycerol kinase, iota | -0.0340408 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0339237 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0338533 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0332878 |
| RPL34 | ribosomal protein L34 | -0.0332715 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0332355 |
| RPLP2 | ribosomal protein, large, P2 | -0.0315839 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0314749 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0314695 |
| RPL35 | ribosomal protein L35 | -0.0308299 |
| RPL9 | ribosomal protein L9 | -0.0306625 |
| RPL11 | ribosomal protein L11 | -0.0305278 |
| RPL8 | ribosomal protein L8 | -0.0303504 |
| TCF12 | transcription factor 12 | -0.0302587 |
| RPL23 | ribosomal protein L23 | -0.0300541 |
| AEBP2 | AE binding protein 2 | -0.0299839 |
| RPS21 | ribosomal protein S21 | -0.0294711 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0292827 |
| PHF14 | PHD finger protein 14 | -0.0292604 |
| MYRFL | myelin regulatory factor-like | -0.0291826 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0287031 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0284668 |
| EXOC4 | exocyst complex component 4 | -0.028333 |
| CUX1 | cut-like homeobox 1 | -0.0278849 |
| DENND1A | DENN/MADD domain containing 1A | -0.0277143 |
| RASAL2 | RAS protein activator like 2 | -0.0271529 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | -0.0270542 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.026818 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0264257 |
| RPLP0 | ribosomal protein, large, P0 | -0.0263987 |
| RPS25 | ribosomal protein S25 | -0.0261794 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0261179 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0256983 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0255394 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0255058 |
| RPL30 | ribosomal protein L30 | -0.0254176 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0252676 |
| ASPH | aspartate beta-hydroxylase | -0.0249863 |
| PLSCR1 | phospholipid scramblase 1 | -0.0249507 |
| COL27A1 | collagen, type XXVII, alpha 1 | -0.0249258 |
| ANK2 | ankyrin 2, neuronal | -0.0247338 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0247062 |
