| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rimonabant (Hydrochloride) perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rimonabant (Hydrochloride)_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.0896623 |
| PDE10A | phosphodiesterase 10A | 0.0733082 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0711088 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0591251 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0518455 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0488016 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0426359 |
| RPL4 | ribosomal protein L4 | 0.0424749 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0417259 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0415899 |
| CENPF | centromere protein F, 350/400kDa | 0.0412446 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0406918 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0402203 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0370214 |
| SET | SET nuclear proto-oncogene | 0.0364908 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.03495 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0346918 |
| VEGFA | vascular endothelial growth factor A | 0.0342252 |
| XPO1 | exportin 1 | 0.0337577 |
| TPM3 | tropomyosin 3 | 0.0336564 |
| MATR3 | matrin 3 | 0.0335777 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0328143 |
| CCNY | cyclin Y | 0.0324054 |
| MED13L | mediator complex subunit 13-like | 0.0313911 |
| MKI67 | marker of proliferation Ki-67 | 0.0311538 |
| CA8 | carbonic anhydrase VIII | 0.0311497 |
| RPS3 | ribosomal protein S3 | 0.0311019 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0308778 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.030726 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0306507 |
| ZNF292 | zinc finger protein 292 | 0.0300838 |
| HMGB2 | high mobility group box 2 | 0.0293642 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0290793 |
| HMGB3 | high mobility group box 3 | 0.028955 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0286747 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0281059 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.027897 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.026564 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0260714 |
| SPAG5 | sperm associated antigen 5 | 0.0258269 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0253725 |
| PCBP3 | poly(rC) binding protein 3 | 0.025144 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 | 0.0249851 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0249425 |
| IRS2 | insulin receptor substrate 2 | 0.0247784 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0246409 |
| DENND1A | DENN/MADD domain containing 1A | 0.0245765 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0244476 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0243781 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.023783 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0236449 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0235908 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.02349 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0232673 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0231025 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0230709 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0229014 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0228642 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0226838 |
| MYEF2 | myelin expression factor 2 | 0.0224515 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0223958 |
| NCKAP1 | NCK-associated protein 1 | 0.0222708 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0222251 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0220091 |
| PCM1 | pericentriolar material 1 | 0.0219274 |
| RPS12 | ribosomal protein S12 | 0.0217196 |
| LMNB1 | lamin B1 | 0.0215629 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0215478 |
| TMSB4X | thymosin beta 4, X-linked | 0.0215448 |
| PTK2 | protein tyrosine kinase 2 | 0.0215034 |
| OGA | O-GlcNAcase | 0.0213427 |
| TSPYL2 | TSPY-like 2 | 0.0211979 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.021168 |
| RPL37 | ribosomal protein L37 | 0.0210729 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0210592 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0208836 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0208309 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0207045 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0206058 |
| RPL7 | ribosomal protein L7 | 0.0202643 |
| NCAM1 | neural cell adhesion molecule 1 | 0.0202272 |
| FAT1 | FAT atypical cadherin 1 | 0.020207 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0201541 |
| YY1AP1 | YY1 associated protein 1 | 0.0201454 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 0.0200084 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0199474 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0198878 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0198392 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0197904 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0196611 |
| NBAS | neuroblastoma amplified sequence | 0.019652 |
| KDM1A | lysine (K)-specific demethylase 1A | 0.0196051 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0195045 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0194821 |
| SYBU | syntabulin (syntaxin-interacting) | 0.0192683 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0192099 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0191582 |
| RRM2 | ribonucleotide reductase M2 | 0.0190067 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0190025 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0189656 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EGR1 | early growth response 1 | -0.0962014 |
| NRG1 | neuregulin 1 | -0.0948258 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.090877 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0827569 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.0735884 |
| STC1 | stanniocalcin 1 | -0.0711857 |
| MAP1B | microtubule-associated protein 1B | -0.0711381 |
| GPC6 | glypican 6 | -0.0668419 |
| SNTG1 | syntrophin, gamma 1 | -0.0618998 |
| NDRG1 | N-myc downstream regulated 1 | -0.0618742 |
| NKAIN2 | Na+/K+ transporting ATPase interacting 2 | -0.0555204 |
| FTL | ferritin, light polypeptide | -0.0523574 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0493651 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.0492861 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0465587 |
| KCNB2 | potassium channel, voltage gated Shab related subfamily B, member 2 | -0.0445539 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0441248 |
| PTCHD4 | patched domain containing 4 | -0.0419522 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0415396 |
| TOX | thymocyte selection-associated high mobility group box | -0.0399132 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0391087 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.039076 |
| PEG10 | paternally expressed 10 | -0.0386618 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0376114 |
| FNDC3A | fibronectin type III domain containing 3A | -0.037566 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0373816 |
| CNKSR3 | CNKSR family member 3 | -0.0372344 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0368333 |
| ACTG1 | actin gamma 1 | -0.0367447 |
| NBEA | neurobeachin | -0.0361953 |
| SMYD3 | SET and MYND domain containing 3 | -0.0353477 |
| MT2A | metallothionein 2A | -0.0344287 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0343994 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | -0.0335644 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0330679 |
| SCG2 | secretogranin II | -0.0320056 |
| RIT2 | Ras-like without CAAX 2 | -0.0296084 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0292337 |
| RPS6 | ribosomal protein S6 | -0.0285795 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0281588 |
| EPHA6 | EPH receptor A6 | -0.0275511 |
| NCKAP5 | NCK-associated protein 5 | -0.0274397 |
| PARM1 | prostate androgen-regulated mucin-like protein 1 | -0.0273 |
| ARFGEF3 | ARFGEF family member 3 | -0.0269312 |
| ST18 | suppression of tumorigenicity 18, zinc finger | -0.0268165 |
| CPE | carboxypeptidase E | -0.0266469 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0266324 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0261351 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0261259 |
| TXNRD1 | thioredoxin reductase 1 | -0.02607 |
| INHBA | inhibin, beta A | -0.0257742 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0256441 |
| SCFD2 | sec1 family domain containing 2 | -0.0256354 |
| RNF213 | ring finger protein 213 | -0.02556 |
| GNAS | GNAS complex locus | -0.0251449 |
| ZNF804A | zinc finger protein 804A | -0.0245199 |
| SYT1 | synaptotagmin I | -0.0243693 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0242652 |
| POTEF | POTE ankyrin domain family, member F | -0.0236875 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | -0.0234499 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0234271 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0230614 |
| NF1 | neurofibromin 1 | -0.0230414 |
| SLC36A4 | solute carrier family 36 (proton/amino acid symporter), member 4 | -0.0229737 |
| PEX5L | peroxisomal biogenesis factor 5-like | -0.022922 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0228922 |
| EFNA5 | ephrin-A5 | -0.0227572 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0227465 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.022568 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 | -0.0223185 |
| KCND2 | potassium channel, voltage gated Shal related subfamily D, member 2 | -0.0222326 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0222011 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0221162 |
| RPL35A | ribosomal protein L35a | -0.0220669 |
| KIF26B | kinesin family member 26B | -0.0219741 |
| CALCA | calcitonin-related polypeptide alpha | -0.0219285 |
| DGKB | diacylglycerol kinase, beta 90kDa | -0.0217751 |
| GPC5 | glypican 5 | -0.0209851 |
| HM13 | histocompatibility (minor) 13 | -0.0209827 |
| POU6F2 | POU class 6 homeobox 2 | -0.0206854 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0206834 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0205702 |
| SSR2 | signal sequence receptor, beta (translocon-associated protein beta) | -0.0204091 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0203181 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0197593 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.019654 |
| RIGI | RNA sensor RIG-I | -0.0193745 |
| NAV2 | neuron navigator 2 | -0.0191443 |
| ESRRG | estrogen-related receptor gamma | -0.0190862 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.01886 |
| ENO1 | enolase 1, (alpha) | -0.0187658 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0187251 |
| SIK2 | salt-inducible kinase 2 | -0.0186609 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0184603 |
| CDK13 | cyclin-dependent kinase 13 | -0.0183582 |
| PFN1 | profilin 1 | -0.0183112 |
| RORA | RAR-related orphan receptor A | -0.01831 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0182699 |
| ZFHX3 | zinc finger homeobox 3 | -0.0182626 |
| PALLD | palladin, cytoskeletal associated protein | -0.0182238 |
