Rimonabant (Hydrochloride)_SW 1088 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Rimonabant (Hydrochloride) perturbation in SW 1088 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Rimonabant (Hydrochloride)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
TRIO trio Rho guanine nucleotide exchange factor 0.0981036
PRELID2 PRELI domain containing 2 0.0643549
KAZN kazrin, periplakin interacting protein 0.0541277
ZCCHC7 zinc finger, CCHC domain containing 7 0.0488235
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.0487958
SDC4 syndecan 4 0.0481824
COL1A1 collagen, type I, alpha 1 0.047772
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.047424
PARD3 par-3 family cell polarity regulator 0.0457184
TPT1 tumor protein, translationally-controlled 1 0.0450354
ZC3HAV1 zinc finger CCCH-type, antiviral 1 0.044745
CDH13 cadherin 13 0.0447108
AHNAK AHNAK nucleoprotein 0.0444921
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 0.0440922
ATXN1 ataxin 1 0.0439052
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0428158
THRAP3 thyroid hormone receptor associated protein 3 0.0420296
OGA O-GlcNAcase 0.0411568
TNS3 tensin 3 0.0409857
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0391056
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0386482
ZEB1 zinc finger E-box binding homeobox 1 0.0383466
LPP LIM domain containing preferred translocation partner in lipoma 0.0382036
ETV6 ets variant 6 0.0380146
ANO6 anoctamin 6 0.0371426
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.0367925
ANKRD17 ankyrin repeat domain 17 0.0356978
FMNL2 formin-like 2 0.0356564
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0350397
SRSF11 serine/arginine-rich splicing factor 11 0.0346776
ANTXR2 anthrax toxin receptor 2 0.0341264
YEATS2 YEATS domain containing 2 0.0340824
ITGAV integrin, alpha V 0.0338978
DST dystonin 0.0336905
MSI2 musashi RNA-binding protein 2 0.0335152
EXOC4 exocyst complex component 4 0.0331896
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0327322
VEGFC vascular endothelial growth factor C 0.0326822
PSD3 pleckstrin and Sec7 domain containing 3 0.0322195
TMSB4X thymosin beta 4, X-linked 0.0316409
ZMYND8 zinc finger, MYND-type containing 8 0.0314473
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 0.0313513
NKD1 naked cuticle homolog 1 (Drosophila) 0.0309901
SYT1 synaptotagmin I 0.0308429
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.030473
NAV1 neuron navigator 1 0.0302644
ZBTB20 zinc finger and BTB domain containing 20 0.030094
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.0299274
NALF1 NALCN channel auxiliary factor 1 0.0298626
SAMD4A sterile alpha motif domain containing 4A 0.0296934
SOD2 superoxide dismutase 2, mitochondrial 0.0296473
VCL vinculin 0.0296222
ANKRD11 ankyrin repeat domain 11 0.0295828
AFDN afadin, adherens junction formation factor 0.029002
OXSR1 oxidative stress responsive 1 0.0286557
NCOR1 nuclear receptor corepressor 1 0.0283834
COL7A1 collagen, type VII, alpha 1 0.0282916
RERE arginine-glutamic acid dipeptide (RE) repeats 0.0279602
RAD51B RAD51 paralog B 0.027555
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 0.0273834
FAM20C family with sequence similarity 20, member C 0.0273557
IGFBP7 insulin-like growth factor binding protein 7 0.027128
GLS2 glutaminase 2 (liver, mitochondrial) 0.0269471
WAC WW domain containing adaptor with coiled-coil 0.0268735
PHF14 PHD finger protein 14 0.0267136
GPBP1L1 GC-rich promoter binding protein 1-like 1 0.0267131
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.0265779
WNK1 WNK lysine deficient protein kinase 1 0.0264203
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0261857
ESYT2 extended synaptotagmin-like protein 2 0.0261416
SDK1 sidekick cell adhesion molecule 1 0.0260954
MAML2 mastermind-like 2 (Drosophila) 0.026007
ZFAND3 zinc finger, AN1-type domain 3 0.0259335
SDC2 syndecan 2 0.0258389
FNIP1 folliculin interacting protein 1 0.0256207
BRAF B-Raf proto-oncogene, serine/threonine kinase 0.0253524
HMGA2 high mobility group AT-hook 2 0.0251273
WAPL WAPL cohesin release factor 0.0249154
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.0248708
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.0248256
FRMD4A FERM domain containing 4A 0.0248014
HOOK3 hook microtubule-tethering protein 3 0.0247007
SENP6 SUMO1/sentrin specific peptidase 6 0.0246974
MYO10 myosin X 0.0246859
MYH9 myosin, heavy chain 9, non-muscle 0.0244879
KIRREL1 kirre like nephrin family adhesion molecule 1 0.024476
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.0242441
MYOF myoferlin 0.0241988
PTK2 protein tyrosine kinase 2 0.0239867
PPP6R3 protein phosphatase 6, regulatory subunit 3 0.0237564
WRN Werner syndrome, RecQ helicase-like 0.0237039
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 0.0235975
SIPA1L1 signal-induced proliferation-associated 1 like 1 0.0235641
AKAP12 A kinase (PRKA) anchor protein 12 0.023409
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.023325
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) 0.023273
BPTF bromodomain PHD finger transcription factor 0.0231575
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 0.023049
WTAP Wilms tumor 1 associated protein 0.0230099
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0225868

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.364218
IGFBP3 insulin-like growth factor binding protein 3 -0.222371
NDRG1 N-myc downstream regulated 1 -0.201884
FTH1 ferritin, heavy polypeptide 1 -0.168069
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.148683
TMSB10 thymosin beta 10 -0.142
FTL ferritin, light polypeptide -0.129887
TGFBI transforming growth factor, beta-induced, 68kDa -0.105274
VIM vimentin -0.087523
LOX lysyl oxidase -0.0835852
B2M beta-2-microglobulin -0.083494
LOC112694756 uncharaterized LOC112694756 -0.081548
MAP1B microtubule-associated protein 1B -0.0813152
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) -0.0727
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -0.0726023
KMT2E lysine (K)-specific methyltransferase 2E -0.0700289
HILPDA hypoxia inducible lipid droplet-associated -0.0657167
ZNF292 zinc finger protein 292 -0.0647269
PKM pyruvate kinase, muscle -0.0623626
MT2A metallothionein 2A -0.0541428
LMAN1 lectin, mannose-binding, 1 -0.0536562
POTEF POTE ankyrin domain family, member F -0.0528156
ENO1 enolase 1, (alpha) -0.0524262
HLA-A major histocompatibility complex, class I, A -0.0506916
RYBP RING1 and YY1 binding protein -0.0473735
PDIA3 protein disulfide isomerase family A, member 3 -0.0468525
ZNF395 zinc finger protein 395 -0.0468441
RPL28 ribosomal protein L28 -0.046569
ADM adrenomedullin -0.0457388
SLC39A14 solute carrier family 39 (zinc transporter), member 14 -0.0450138
PFN1 profilin 1 -0.0439818
TRA2A transformer 2 alpha homolog (Drosophila) -0.0437876
WASF2 WAS protein family, member 2 -0.0429112
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0427602
CALR calreticulin -0.0426778
LGALS1 lectin, galactoside-binding, soluble, 1 -0.0421644
CCNI cyclin I -0.0419642
MARCHF6 membrane associated ring-CH-type finger 6 -0.0407948
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.040716
SEC31A SEC31 homolog A (S. cerevisiae) -0.040516
NAMPT nicotinamide phosphoribosyltransferase -0.0397998
ANKRD37 ankyrin repeat domain 37 -0.0394602
COL6A1 collagen, type VI, alpha 1 -0.0380951
STC1 stanniocalcin 1 -0.0377687
ECE1 endothelin converting enzyme 1 -0.0365726
TPI1 triosephosphate isomerase 1 -0.0358001
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -0.0356605
BHLHE40 basic helix-loop-helix family, member e40 -0.0349225
S100A10 S100 calcium binding protein A10 -0.0347643
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.0345845
FKBP10 FK506 binding protein 10, 65 kDa -0.0344131
GNAS GNAS complex locus -0.0339203
MEF2A myocyte enhancer factor 2A -0.0336011
COPB2 coatomer protein complex, subunit beta 2 (beta prime) -0.0332238
CAV1 caveolin 1, caveolae protein, 22kDa -0.0331913
CD99 CD99 molecule -0.0331882
ITM2B integral membrane protein 2B -0.0329116
BSG basigin (Ok blood group) -0.0327116
SQSTM1 sequestosome 1 -0.0326795
CCNL1 cyclin L1 -0.0326701
RPL5 ribosomal protein L5 -0.0320261
RAB7A RAB7A, member RAS oncogene family -0.0308313
AKAP9 A kinase (PRKA) anchor protein 9 -0.0306947
GPBP1 GC-rich promoter binding protein 1 -0.0301501
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.0301086
CD44 CD44 molecule (Indian blood group) -0.0298114
TAGLN2 transgelin 2 -0.0297208
TGDS TDP-glucose 4,6-dehydratase -0.0290567
EPAS1 endothelial PAS domain protein 1 -0.0289462
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.0286384
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.0285959
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0285539
AP2B1 adaptor-related protein complex 2, beta 1 subunit -0.0280121
PPDPF pancreatic progenitor cell differentiation and proliferation factor -0.027747
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 -0.0273263
FNDC3A fibronectin type III domain containing 3A -0.0268293
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -0.0264906
ACBD3 acyl-CoA binding domain containing 3 -0.0260501
PDIA6 protein disulfide isomerase family A, member 6 -0.0258503
UGP2 UDP-glucose pyrophosphorylase 2 -0.0254325
TTC3 tetratricopeptide repeat domain 3 -0.0252242
TLN1 talin 1 -0.025022
SETD5 SET domain containing 5 -0.0249499
EPRS1 glutamyl-prolyl-tRNA synthetase 1 -0.0248297
HLA-C major histocompatibility complex, class I, C -0.024806
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.0246956
FNDC3B fibronectin type III domain containing 3B -0.0246334
NMD3 NMD3 ribosome export adaptor -0.0244814
RRBP1 ribosome binding protein 1 -0.0243749
TMBIM6 transmembrane BAX inhibitor motif containing 6 -0.0243616
GOLGA4 golgin A4 -0.0242823
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 -0.0241226
TIMP2 TIMP metallopeptidase inhibitor 2 -0.0238869
ERLEC1 endoplasmic reticulum lectin 1 -0.0238169
HIP1 huntingtin interacting protein 1 -0.0238052
CST3 cystatin C -0.0237815
TFRC transferrin receptor -0.0235687
GRID1 glutamate receptor, ionotropic, delta 1 -0.0233746
ARRDC3 arrestin domain containing 3 -0.0233621
UBXN4 UBX domain protein 4 -0.0231565