| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rimonabant perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rimonabant_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP1B | microtubule-associated protein 1B | 0.110097 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.107724 |
| PLAT | plasminogen activator, tissue | 0.102912 |
| COL5A1 | collagen, type V, alpha 1 | 0.0962428 |
| DST | dystonin | 0.0944001 |
| CDH13 | cadherin 13 | 0.0856391 |
| FLNA | filamin A, alpha | 0.082125 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0819871 |
| PODXL | podocalyxin-like | 0.0779132 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.072734 |
| RNF213 | ring finger protein 213 | 0.0724281 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0698087 |
| PRELID2 | PRELI domain containing 2 | 0.0666631 |
| HDAC9 | histone deacetylase 9 | 0.065663 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0648805 |
| MX2 | MX dynamin-like GTPase 2 | 0.0643153 |
| RIGI | RNA sensor RIG-I | 0.062533 |
| NAV1 | neuron navigator 1 | 0.0622646 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0600608 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0562831 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0538294 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0537902 |
| SP100 | SP100 nuclear antigen | 0.0537819 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0531152 |
| FN1 | fibronectin 1 | 0.0524934 |
| CD44 | CD44 molecule (Indian blood group) | 0.0523405 |
| AHNAK | AHNAK nucleoprotein | 0.0489432 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0488456 |
| FSTL1 | follistatin-like 1 | 0.0474759 |
| PRSS23 | protease, serine, 23 | 0.0459192 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0458116 |
| PLEC | plectin | 0.0454994 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0451365 |
| LOX | lysyl oxidase | 0.0450023 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0443798 |
| INTS6 | integrator complex subunit 6 | 0.043916 |
| VEGFC | vascular endothelial growth factor C | 0.043048 |
| NEK7 | NIMA-related kinase 7 | 0.0428736 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0426444 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0423057 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0420364 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0416886 |
| EGFR | epidermal growth factor receptor | 0.0411769 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.0405887 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.040187 |
| PLXNA2 | plexin A2 | 0.0396665 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0393419 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0389156 |
| GLIS3 | GLIS family zinc finger 3 | 0.0367385 |
| L1CAM | L1 cell adhesion molecule | 0.036521 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0362035 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0361961 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0358467 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0356254 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0354218 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0354062 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0353996 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0351087 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0347372 |
| PCDH7 | protocadherin 7 | 0.0345694 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0344484 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0342941 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0342056 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0340675 |
| JAZF1 | JAZF zinc finger 1 | 0.0337762 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0327639 |
| ADAR | adenosine deaminase, RNA-specific | 0.0327049 |
| RASAL2 | RAS protein activator like 2 | 0.0325776 |
| EFNA5 | ephrin-A5 | 0.0320972 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0320784 |
| GOLGB1 | golgin B1 | 0.0319497 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0318724 |
| MB21D2 | Mab-21 domain containing 2 | 0.0317027 |
| DCLK2 | doublecortin-like kinase 2 | 0.0312195 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0310499 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0295295 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0294088 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0293787 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0293518 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0290648 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.0289352 |
| CLTC | clathrin, heavy chain (Hc) | 0.0283756 |
| MYOF | myoferlin | 0.0283352 |
| SON | SON DNA binding protein | 0.0282486 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.028174 |
| E2F7 | E2F transcription factor 7 | 0.0279936 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.0278914 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0278026 |
| TLE4 | transducin-like enhancer of split 4 | 0.0276512 |
| NIBAN1 | niban apoptosis regulator 1 | 0.0274545 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0273237 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF | 0.0269732 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0266208 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0265503 |
| VCL | vinculin | 0.0261581 |
| HDLBP | high density lipoprotein binding protein | 0.0259447 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0257903 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0256653 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0256122 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0255918 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.220943 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.128839 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.121178 |
| PTMA | prothymosin, alpha | -0.0972507 |
| S100A6 | S100 calcium binding protein A6 | -0.0825734 |
| UBC | ubiquitin C | -0.078454 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0666124 |
| TPM4 | tropomyosin 4 | -0.0661053 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0627872 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0615613 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0521946 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0512539 |
| ANXA2 | annexin A2 | -0.0481842 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0480347 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0464915 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.045641 |
| NDRG1 | N-myc downstream regulated 1 | -0.0450225 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.043705 |
| MT2A | metallothionein 2A | -0.0422894 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | -0.0419943 |
| RPS6 | ribosomal protein S6 | -0.0407322 |
| FTL | ferritin, light polypeptide | -0.0403674 |
| TMSB10 | thymosin beta 10 | -0.039919 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0396302 |
| CD99 | CD99 molecule | -0.0390139 |
| CCND1 | cyclin D1 | -0.0383217 |
| COL3A1 | collagen, type III, alpha 1 | -0.0373888 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0361965 |
| CD109 | CD109 molecule | -0.035888 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0346341 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0345468 |
| RPS8 | ribosomal protein S8 | -0.034461 |
| CSTB | cystatin B (stefin B) | -0.034123 |
| RAI1 | retinoic acid induced 1 | -0.0337977 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0335014 |
| RTN4 | reticulon 4 | -0.0333386 |
| JUN | jun proto-oncogene | -0.0332234 |
| INSIG1 | insulin induced gene 1 | -0.0330391 |
| RPS27A | ribosomal protein S27a | -0.0329423 |
| RPL23 | ribosomal protein L23 | -0.0328668 |
| RPL37A | ribosomal protein L37a | -0.0324144 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0322447 |
| GOLGA4 | golgin A4 | -0.0318197 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -0.0314638 |
| RPLP1 | ribosomal protein, large, P1 | -0.0312105 |
| FAM107B | family with sequence similarity 107, member B | -0.0294911 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.029435 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0291333 |
| VDAC1 | voltage-dependent anion channel 1 | -0.028297 |
| ADM | adrenomedullin | -0.0282562 |
| STC1 | stanniocalcin 1 | -0.0281917 |
| RPL12 | ribosomal protein L12 | -0.027703 |
| MYADM | myeloid-associated differentiation marker | -0.0274053 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0273499 |
| RPS3 | ribosomal protein S3 | -0.0272228 |
| RPL35A | ribosomal protein L35a | -0.0269748 |
| SBF2 | SET binding factor 2 | -0.0264414 |
| CAVIN1 | caveolae associated protein 1 | -0.0262984 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0261589 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0260179 |
| S100A10 | S100 calcium binding protein A10 | -0.0258262 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0252765 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0252283 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0250988 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0250598 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0250506 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0243023 |
| TMSB4X | thymosin beta 4, X-linked | -0.0239356 |
| CALR | calreticulin | -0.023681 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.023585 |
| RPL26 | ribosomal protein L26 | -0.0233351 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0232631 |
| RPS12 | ribosomal protein S12 | -0.0231671 |
| RPL19 | ribosomal protein L19 | -0.0228623 |
| HLA-E | major histocompatibility complex, class I, E | -0.0228015 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0226368 |
| RPL28 | ribosomal protein L28 | -0.0225194 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.022012 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0218026 |
| RPLP2 | ribosomal protein, large, P2 | -0.0217824 |
| SQSTM1 | sequestosome 1 | -0.0216231 |
| MMP12 | matrix metallopeptidase 12 | -0.0213721 |
| RPL37 | ribosomal protein L37 | -0.0213366 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0213089 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0213068 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0212446 |
| WDR45B | WD repeat domain 45B | -0.0209834 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | -0.0209702 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0207527 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0207256 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0207182 |
| RPS2 | ribosomal protein S2 | -0.0207109 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0205353 |
| RPL34 | ribosomal protein L34 | -0.020526 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0204699 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0204252 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.0203506 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0201322 |
| GGNBP2 | gametogenetin binding protein 2 | -0.0200252 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0198315 |
