| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rimonabant perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rimonabant_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.200651 |
| NLGN1 | neuroligin 1 | 0.19193 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.191242 |
| YAP1 | Yes-associated protein 1 | 0.0999724 |
| PDGFC | platelet derived growth factor C | 0.0861257 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0763823 |
| HMGA2 | high mobility group AT-hook 2 | 0.067213 |
| TMSB10 | thymosin beta 10 | 0.0630552 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0608141 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0572601 |
| YBX3 | Y box binding protein 3 | 0.0552143 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0543878 |
| RCOR1 | REST corepressor 1 | 0.0543637 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.053431 |
| RRM2 | ribonucleotide reductase M2 | 0.0497522 |
| INTS6 | integrator complex subunit 6 | 0.0487748 |
| CMIP | c-Maf inducing protein | 0.0478853 |
| PCDH7 | protocadherin 7 | 0.0476916 |
| TENM3 | teneurin transmembrane protein 3 | 0.0463515 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0438996 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.041796 |
| AREG | amphiregulin | 0.0395084 |
| TEAD4 | TEA domain family member 4 | 0.0382804 |
| TMEM41B | transmembrane protein 41B | 0.0371066 |
| ADIPOR2 | adiponectin receptor 2 | 0.0369183 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0366802 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0364496 |
| DIAPH3 | diaphanous-related formin 3 | 0.03609 |
| WWOX | WW domain containing oxidoreductase | 0.0352382 |
| ACTG1 | actin gamma 1 | 0.0350013 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0348168 |
| MYPN | myopalladin | 0.0335083 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.0330581 |
| KDM5A | lysine (K)-specific demethylase 5A | 0.0330271 |
| DENND5A | DENN/MADD domain containing 5A | 0.0330042 |
| NUP98 | nucleoporin 98kDa | 0.0327481 |
| EGR1 | early growth response 1 | 0.0322604 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0316098 |
| EDARADD | EDAR-associated death domain | 0.0304275 |
| PRKCE | protein kinase C, epsilon | 0.0304112 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0303669 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0290235 |
| RPL3 | ribosomal protein L3 | 0.0289686 |
| BRD4 | bromodomain containing 4 | 0.0286525 |
| FADS2 | fatty acid desaturase 2 | 0.028115 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0281079 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0280509 |
| FLNA | filamin A, alpha | 0.0280508 |
| ZNF638 | zinc finger protein 638 | 0.0280397 |
| HDAC9 | histone deacetylase 9 | 0.0275983 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0275044 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0274974 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.027427 |
| TJP1 | tight junction protein 1 | 0.0272907 |
| MED13L | mediator complex subunit 13-like | 0.0268653 |
| NEGR1 | neuronal growth regulator 1 | 0.0265338 |
| SERTAD2 | SERTA domain containing 2 | 0.0261538 |
| KIF4A | kinesin family member 4A | 0.0261467 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0260371 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0260026 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0259243 |
| VCL | vinculin | 0.0259172 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0255167 |
| RTN4 | reticulon 4 | 0.0255037 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0253854 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.0252877 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0252163 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 0.0251718 |
| RAB5B | RAB5B, member RAS oncogene family | 0.0251093 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0249203 |
| POLE | polymerase (DNA directed), epsilon, catalytic subunit | 0.0248707 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0248229 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0247919 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0247879 |
| PCBP2 | poly(rC) binding protein 2 | 0.0246467 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) | 0.0244987 |
| NFIB | nuclear factor I/B | 0.0241241 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0241119 |
| FAT1 | FAT atypical cadherin 1 | 0.0239075 |
| JMJD1C | jumonji domain containing 1C | 0.0234753 |
| FASN | fatty acid synthase | 0.0233421 |
| FAM193A | family with sequence similarity 193, member A | 0.0232557 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0232491 |
| RPL23 | ribosomal protein L23 | 0.0231473 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0229466 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0228886 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | 0.0228289 |
| PFN1 | profilin 1 | 0.0226267 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0226248 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0225609 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0220802 |
| PCM1 | pericentriolar material 1 | 0.0220284 |
| NABP1 | nucleic acid binding protein 1 | 0.0218524 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0218385 |
| RACGAP1 | Rac GTPase activating protein 1 | 0.0218324 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0217515 |
| POTEF | POTE ankyrin domain family, member F | 0.0217468 |
| SRSF3 | serine/arginine-rich splicing factor 3 | 0.0216577 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0213968 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0212764 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.262604 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.128657 |
| PTMA | prothymosin, alpha | -0.081812 |
| ANXA1 | annexin A1 | -0.0799508 |
| EHBP1 | EH domain binding protein 1 | -0.0787176 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0697584 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0669237 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0597959 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0592055 |
| ENO1 | enolase 1, (alpha) | -0.0535675 |
| TMEM123 | transmembrane protein 123 | -0.0529651 |
| CLDN1 | claudin 1 | -0.0523046 |
| S100A6 | S100 calcium binding protein A6 | -0.0521263 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0517535 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0503919 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0498557 |
| ASPH | aspartate beta-hydroxylase | -0.0488973 |
| RPS6 | ribosomal protein S6 | -0.0474883 |
| AHNAK | AHNAK nucleoprotein | -0.0465272 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0463146 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0462926 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0437175 |
| RPS27A | ribosomal protein S27a | -0.0426772 |
| RPS8 | ribosomal protein S8 | -0.0426191 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0391699 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0388232 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0384989 |
| RPLP1 | ribosomal protein, large, P1 | -0.0382425 |
| LDHA | lactate dehydrogenase A | -0.0374772 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0374171 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0370218 |
| WDR45B | WD repeat domain 45B | -0.0368778 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0357034 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0350888 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0349825 |
| KIF5B | kinesin family member 5B | -0.0348857 |
| SEPTIN7 | septin 7 | -0.0348367 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0348109 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0344985 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0340528 |
| PGK1 | phosphoglycerate kinase 1 | -0.0338942 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0337277 |
| HMGA1 | high mobility group AT-hook 1 | -0.0336819 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0333951 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0333376 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0332792 |
| RPLP0 | ribosomal protein, large, P0 | -0.0332426 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0329886 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0328759 |
| MMP12 | matrix metallopeptidase 12 | -0.0319667 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0316977 |
| ZNF292 | zinc finger protein 292 | -0.0312271 |
| CANX | calnexin | -0.0311282 |
| USP53 | ubiquitin specific peptidase 53 | -0.0309054 |
| RPS16 | ribosomal protein S16 | -0.0305985 |
| RPL34 | ribosomal protein L34 | -0.0298963 |
| YBX1 | Y box binding protein 1 | -0.0298503 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0293346 |
| RPS20 | ribosomal protein S20 | -0.0291103 |
| DSPP | dentin sialophosphoprotein | -0.0290506 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0288527 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0283404 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0281879 |
| RPL35A | ribosomal protein L35a | -0.0280147 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0276632 |
| TPM4 | tropomyosin 4 | -0.0275091 |
| RPS13 | ribosomal protein S13 | -0.0274596 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | -0.0273316 |
| FTL | ferritin, light polypeptide | -0.0269506 |
| H1-0 | H1.0 linker histone | -0.0269141 |
| RHOA | ras homolog family member A | -0.0264527 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0264365 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.026341 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.0260232 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0260166 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0259866 |
| RPL19 | ribosomal protein L19 | -0.0259797 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0259194 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0257188 |
| CAVIN1 | caveolae associated protein 1 | -0.0256013 |
| RPL39 | ribosomal protein L39 | -0.0254966 |
| ZFR | zinc finger RNA binding protein | -0.0254932 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0254561 |
| RAI14 | retinoic acid induced 14 | -0.0254435 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0252644 |
| ANXA2 | annexin A2 | -0.0252166 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.025123 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0250842 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0247334 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0246101 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0244872 |
| RPS24 | ribosomal protein S24 | -0.0243316 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0242108 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0241541 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0240143 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0240119 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.0237329 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0237211 |
| HIP1 | huntingtin interacting protein 1 | -0.0236564 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.0234025 |
