| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rimonabant perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rimonabant_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GLCCI1 | glucocorticoid induced 1 | 0.0842491 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0782468 |
| TLE4 | transducin-like enhancer of split 4 | 0.069168 |
| MEIS2 | Meis homeobox 2 | 0.068174 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0650496 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0619501 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0616249 |
| CLTC | clathrin, heavy chain (Hc) | 0.0565571 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0550814 |
| MRTFA | myocardin related transcription factor A | 0.0523341 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0517609 |
| IGF2 | insulin-like growth factor 2 | 0.0475661 |
| ZNF609 | zinc finger protein 609 | 0.0474561 |
| TPR | translocated promoter region, nuclear basket protein | 0.0471498 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | 0.0467442 |
| APP | amyloid beta (A4) precursor protein | 0.0466536 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0462739 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0462007 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0449505 |
| PLPP1 | phospholipid phosphatase 1 | 0.044122 |
| MAP1B | microtubule-associated protein 1B | 0.043593 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.0431785 |
| FMN1 | formin 1 | 0.0431268 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0415472 |
| FLNA | filamin A, alpha | 0.0415167 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0406422 |
| PLAT | plasminogen activator, tissue | 0.0405403 |
| DST | dystonin | 0.0402406 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 0.0397433 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0391536 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0387475 |
| DUSP10 | dual specificity phosphatase 10 | 0.0383605 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0382099 |
| SETBP1 | SET binding protein 1 | 0.0377387 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0375783 |
| SP100 | SP100 nuclear antigen | 0.0371605 |
| DGKH | diacylglycerol kinase, eta | 0.0368014 |
| MEF2D | myocyte enhancer factor 2D | 0.0366284 |
| HOMER1 | homer scaffolding protein 1 | 0.0357072 |
| FOXP1 | forkhead box P1 | 0.035437 |
| PKM | pyruvate kinase, muscle | 0.035222 |
| PCDH9 | protocadherin 9 | 0.0343151 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0340291 |
| MYO6 | myosin VI | 0.0338429 |
| CENPF | centromere protein F, 350/400kDa | 0.0334729 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.0334342 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0326501 |
| SET | SET nuclear proto-oncogene | 0.032453 |
| VEGFA | vascular endothelial growth factor A | 0.0320155 |
| ATP10D | ATPase, class V, type 10D | 0.031931 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.031222 |
| STK38L | serine/threonine kinase 38 like | 0.0310979 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0307833 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0302404 |
| PCM1 | pericentriolar material 1 | 0.030126 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0300459 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0300144 |
| MMP2 | matrix metallopeptidase 2 | 0.0300054 |
| MED13 | mediator complex subunit 13 | 0.0298731 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0297261 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0296955 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | 0.0296095 |
| RC3H1 | ring finger and CCCH-type domains 1 | 0.0294454 |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) | 0.0290515 |
| PKP4 | plakophilin 4 | 0.0288505 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0287996 |
| AOPEP | aminopeptidase O (putative) | 0.0285681 |
| KLHL13 | kelch-like family member 13 | 0.0284959 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0281343 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0281336 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.0281231 |
| NRP1 | neuropilin 1 | 0.0277815 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0277773 |
| ITGAV | integrin, alpha V | 0.0273775 |
| ADAR | adenosine deaminase, RNA-specific | 0.0273746 |
| RIGI | RNA sensor RIG-I | 0.0273397 |
| THBS1 | thrombospondin 1 | 0.0272635 |
| RET | ret proto-oncogene | 0.02706 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0264945 |
| AUTS2 | autism susceptibility candidate 2 | 0.0264931 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0263951 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.026392 |
| MTSS2 | MTSS I-BAR domain containing 2 | 0.0260066 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.025913 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0258946 |
| PLEC | plectin | 0.0255741 |
| DSTN | destrin (actin depolymerizing factor) | 0.0255026 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0254621 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0252921 |
| SYNPO2 | synaptopodin 2 | 0.0250702 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.025005 |
| RNF213 | ring finger protein 213 | 0.0248904 |
| CDK19 | cyclin-dependent kinase 19 | 0.0248253 |
| ZRANB1 | zinc finger, RAN-binding domain containing 1 | 0.0247645 |
| FHL2 | four and a half LIM domains 2 | 0.024592 |
| PPP4R2 | protein phosphatase 4, regulatory subunit 2 | 0.0244871 |
| FHIT | fragile histidine triad | 0.0243045 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0242157 |
| FERMT2 | fermitin family member 2 | 0.0240004 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0239816 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LSAMP | limbic system-associated membrane protein | -0.207124 |
| NRG1 | neuregulin 1 | -0.107087 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.104393 |
| PTMA | prothymosin, alpha | -0.0851143 |
| TRIB2 | tribbles pseudokinase 2 | -0.0727554 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0656528 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0652255 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0650536 |
| VCL | vinculin | -0.0649297 |
| RPL23 | ribosomal protein L23 | -0.0623077 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0600934 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0592413 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0586402 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | -0.0580776 |
| RPS24 | ribosomal protein S24 | -0.0556848 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0544907 |
| FRMD4A | FERM domain containing 4A | -0.0524737 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0519809 |
| RPL19 | ribosomal protein L19 | -0.0516355 |
| RPS6 | ribosomal protein S6 | -0.0515064 |
| ATRNL1 | attractin-like 1 | -0.050621 |
| SMYD3 | SET and MYND domain containing 3 | -0.0484012 |
| RPL37A | ribosomal protein L37a | -0.0481046 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0469024 |
| ENO1 | enolase 1, (alpha) | -0.0461524 |
| GPC5 | glypican 5 | -0.0454033 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.045234 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0446464 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0446037 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0436205 |
| CADM2 | cell adhesion molecule 2 | -0.0414739 |
| COL4A6 | collagen, type IV, alpha 6 | -0.040806 |
| RNF150 | ring finger protein 150 | -0.0402974 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0385257 |
| DTNA | dystrobrevin, alpha | -0.0384251 |
| RPL34 | ribosomal protein L34 | -0.0378885 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0366163 |
| NREP | neuronal regeneration related protein | -0.0359104 |
| EGFR | epidermal growth factor receptor | -0.0358269 |
| RPL31 | ribosomal protein L31 | -0.0353577 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0349221 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0347151 |
| RPLP1 | ribosomal protein, large, P1 | -0.0342596 |
| MORF4L2 | mortality factor 4 like 2 | -0.033825 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0336048 |
| ACBD6 | acyl-CoA binding domain containing 6 | -0.0334627 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0333481 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0330234 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0327586 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0326458 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0325871 |
| RPL26 | ribosomal protein L26 | -0.0323397 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0322221 |
| RPS12 | ribosomal protein S12 | -0.0319842 |
| RPL9 | ribosomal protein L9 | -0.031983 |
| RPLP0 | ribosomal protein, large, P0 | -0.0319377 |
| RPL13A | ribosomal protein L13a | -0.0315997 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0314186 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0312499 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0312164 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0311551 |
| RBBP6 | retinoblastoma binding protein 6 | -0.0310006 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0304634 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0304496 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0302886 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | -0.0300324 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0296458 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0295614 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0295175 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0292353 |
| RPS27 | ribosomal protein S27 | -0.029213 |
| ATXN10 | ataxin 10 | -0.0286937 |
| HELZ | helicase with zinc finger | -0.02831 |
| ZNF124 | zinc finger protein 124 | -0.0282342 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0280898 |
| RPL28 | ribosomal protein L28 | -0.0280337 |
| NPR2 | natriuretic peptide receptor 2 | -0.0279267 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0278573 |
| SBF2 | SET binding factor 2 | -0.0277807 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0276433 |
| VIM | vimentin | -0.0276196 |
| DENND4A | DENN/MADD domain containing 4A | -0.0275058 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0272809 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0271834 |
| NBEAL1 | neurobeachin-like 1 | -0.0271336 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0270431 |
| CDH13 | cadherin 13 | -0.0269472 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0268962 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.0268936 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0268635 |
| MCL1 | myeloid cell leukemia 1 | -0.0268122 |
| IER3 | immediate early response 3 | -0.0267356 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0266839 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | -0.0265637 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0265504 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0263947 |
| AHR | aryl hydrocarbon receptor | -0.0260891 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0259891 |
| RPS19 | ribosomal protein S19 | -0.0259516 |
| H1-0 | H1.0 linker histone | -0.0258505 |