| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rimonabant perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rimonabant_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.34533 |
| FN1 | fibronectin 1 | 0.262561 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.153255 |
| PLEC | plectin | 0.0838413 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0812173 |
| CDH13 | cadherin 13 | 0.0756929 |
| FLNA | filamin A, alpha | 0.0641032 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0582366 |
| COL1A1 | collagen, type I, alpha 1 | 0.0563396 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0493 |
| TMSB10 | thymosin beta 10 | 0.0467342 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0442223 |
| COL5A1 | collagen, type V, alpha 1 | 0.039658 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.037437 |
| MT1X | metallothionein 1X | 0.0360497 |
| VCL | vinculin | 0.0354452 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0340259 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | 0.0303663 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0303456 |
| JAG1 | jagged 1 | 0.0300721 |
| NAV2 | neuron navigator 2 | 0.0294186 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0291164 |
| INTS6 | integrator complex subunit 6 | 0.0278869 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0264663 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0262125 |
| CNTN5 | contactin 5 | 0.0254047 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0245852 |
| EPHB1 | EPH receptor B1 | 0.0237884 |
| HDAC9 | histone deacetylase 9 | 0.0236044 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0235834 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0230552 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0215774 |
| RIGI | RNA sensor RIG-I | 0.0212461 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0210447 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0207906 |
| GANAB | glucosidase, alpha; neutral AB | 0.0207131 |
| HYOU1 | hypoxia up-regulated 1 | 0.0206702 |
| AHNAK | AHNAK nucleoprotein | 0.0205501 |
| ITGAV | integrin, alpha V | 0.0205081 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0203376 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0200489 |
| RSU1 | Ras suppressor protein 1 | 0.0198513 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0195528 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0192028 |
| CALD1 | caldesmon 1 | 0.0191378 |
| ACTN1 | actinin, alpha 1 | 0.0190657 |
| ACTG1 | actin gamma 1 | 0.0189958 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0188818 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0187219 |
| JAK2 | Janus kinase 2 | 0.0186973 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0184417 |
| EGR1 | early growth response 1 | 0.0184328 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0180333 |
| TUBB | tubulin, beta class I | 0.0179777 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0171202 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0170435 |
| SUMF1 | sulfatase modifying factor 1 | 0.017016 |
| NEK10 | NIMA-related kinase 10 | 0.0169367 |
| ADAM12 | ADAM metallopeptidase domain 12 | 0.0168664 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.016498 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0162083 |
| PALLD | palladin, cytoskeletal associated protein | 0.0161637 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0158589 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0157769 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0157356 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0157083 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0152922 |
| GATAD2A | GATA zinc finger domain containing 2A | 0.0152896 |
| NABP1 | nucleic acid binding protein 1 | 0.0150798 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0149571 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0149346 |
| PRSS23 | protease, serine, 23 | 0.0146703 |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha | 0.014664 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0146257 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0146251 |
| DGKI | diacylglycerol kinase, iota | 0.01454 |
| SRCAP | Snf2-related CREBBP activator protein | 0.0145148 |
| IFNGR2 | interferon gamma receptor 2 (interferon gamma transducer 1) | 0.0142788 |
| MYL9 | myosin, light chain 9, regulatory | 0.0142404 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.0141958 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0141863 |
| COL5A3 | collagen, type V, alpha 3 | 0.0141312 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.01388 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.013875 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0138563 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.013843 |
| ATXN1 | ataxin 1 | 0.0137851 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.0135288 |
| SETBP1 | SET binding protein 1 | 0.0135231 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0135007 |
| KLF6 | Kruppel-like factor 6 | 0.0134695 |
| RPN2 | ribophorin II | 0.0134293 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0133089 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.013287 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0132685 |
| RAD51B | RAD51 paralog B | 0.0131279 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0131118 |
| DST | dystonin | 0.0130452 |
| SMIM44 | small integral membrane protein 44 | 0.0129861 |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 | 0.0129793 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.170093 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.139815 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.12508 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.109246 |
| COL1A2 | collagen, type I, alpha 2 | -0.101132 |
| PDE10A | phosphodiesterase 10A | -0.0916955 |
| GOLGA4 | golgin A4 | -0.08643 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.083045 |
| VIM | vimentin | -0.0804404 |
| CD44 | CD44 molecule (Indian blood group) | -0.076533 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0731505 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.069127 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0670199 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0648418 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0603653 |
| STC1 | stanniocalcin 1 | -0.0597113 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0570206 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0567419 |
| VEGFA | vascular endothelial growth factor A | -0.0566038 |
| TPM4 | tropomyosin 4 | -0.0564523 |
| CANX | calnexin | -0.0553364 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0535726 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0534924 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.052798 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0515888 |
| RPS2 | ribosomal protein S2 | -0.0513066 |
| GOLGB1 | golgin B1 | -0.0512527 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0508322 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0507422 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0500297 |
| TMF1 | TATA element modulatory factor 1 | -0.0490997 |
| ENO1 | enolase 1, (alpha) | -0.0488502 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.048073 |
| MT2A | metallothionein 2A | -0.0475614 |
| SPAG9 | sperm associated antigen 9 | -0.0466284 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0462358 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.045076 |
| RPS6 | ribosomal protein S6 | -0.0449984 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0447949 |
| LDHA | lactate dehydrogenase A | -0.0443316 |
| MTDH | metadherin | -0.0427565 |
| FBXO32 | F-box protein 32 | -0.0394913 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0391858 |
| RPS8 | ribosomal protein S8 | -0.0391762 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0370141 |
| ZNF292 | zinc finger protein 292 | -0.0367155 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0360177 |
| LOXL2 | lysyl oxidase-like 2 | -0.0359181 |
| RTN4 | reticulon 4 | -0.0357523 |
| UBC | ubiquitin C | -0.0354502 |
| LOX | lysyl oxidase | -0.0345544 |
| SBF2 | SET binding factor 2 | -0.0338975 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0329854 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0329213 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0328458 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0327915 |
| CADM1 | cell adhesion molecule 1 | -0.032356 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0317973 |
| SEC24A | SEC24 family member A | -0.0317071 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0316561 |
| XPO1 | exportin 1 | -0.0315424 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0314176 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0314115 |
| ARRDC3 | arrestin domain containing 3 | -0.0311022 |
| RPL7 | ribosomal protein L7 | -0.0307479 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0307418 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0305753 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0304974 |
| TMEM165 | transmembrane protein 165 | -0.0294966 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0294476 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0293595 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0291039 |
| ADM | adrenomedullin | -0.0290361 |
| IL6 | interleukin 6 | -0.0290333 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0287158 |
| SRP54 | signal recognition particle 54kDa | -0.0286583 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0286515 |
| RPL37A | ribosomal protein L37a | -0.0285949 |
| TRAM1 | translocation associated membrane protein 1 | -0.0285878 |
| RBM39 | RNA binding motif protein 39 | -0.0272814 |
| SETD5 | SET domain containing 5 | -0.0272216 |
| MTSS1 | metastasis suppressor 1 | -0.0272157 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0272008 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.027077 |
| MYO9B | myosin IXB | -0.0270109 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0266412 |
| CTSB | cathepsin B | -0.026469 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0263095 |
| SMAD3 | SMAD family member 3 | -0.0260349 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0258992 |
| FAM107B | family with sequence similarity 107, member B | -0.025449 |
| BBX | bobby sox homolog (Drosophila) | -0.0252445 |
| CLTC | clathrin, heavy chain (Hc) | -0.0251947 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0251751 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0250083 |
| FAM13B | family with sequence similarity 13, member B | -0.0247869 |
| CALR | calreticulin | -0.0245701 |
| VCAN | versican | -0.0245192 |
| KIF1B | kinesin family member 1B | -0.0243082 |
| SQLE | squalene epoxidase | -0.0238707 |
