| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rimonabant perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rimonabant_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.227944 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.144415 |
| FN1 | fibronectin 1 | 0.109906 |
| ATXN1 | ataxin 1 | 0.0989568 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0974778 |
| FOXP1 | forkhead box P1 | 0.0862432 |
| FAM107B | family with sequence similarity 107, member B | 0.0843433 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0730129 |
| BCL2L1 | BCL2-like 1 | 0.0726835 |
| VCL | vinculin | 0.0670984 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0651871 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0650245 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0550294 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0526141 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0485329 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0481595 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0481034 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0480805 |
| ITGAV | integrin, alpha V | 0.0478532 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0476604 |
| DST | dystonin | 0.0470509 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0462525 |
| FLNA | filamin A, alpha | 0.0451913 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0446145 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0439066 |
| SMAD3 | SMAD family member 3 | 0.0437621 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0437143 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0433558 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0422556 |
| PTCHD4 | patched domain containing 4 | 0.0422553 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0416198 |
| ACTG1 | actin gamma 1 | 0.0415598 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0401387 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0400915 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0400801 |
| INTS6 | integrator complex subunit 6 | 0.0396255 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0395315 |
| HDAC4 | histone deacetylase 4 | 0.0391312 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0390488 |
| CMIP | c-Maf inducing protein | 0.0383425 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0381837 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0372788 |
| CADM1 | cell adhesion molecule 1 | 0.0363502 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0359153 |
| KYNU | kynureninase | 0.0358233 |
| ASPH | aspartate beta-hydroxylase | 0.0356974 |
| ACTN4 | actinin, alpha 4 | 0.0349108 |
| RSU1 | Ras suppressor protein 1 | 0.0348494 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0347529 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0346326 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0343174 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0342824 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0333877 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0328135 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0326498 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0320919 |
| DNAH17 | dynein, axonemal, heavy chain 17 | 0.0312547 |
| SEPTIN9 | septin 9 | 0.0310333 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0310196 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0307922 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0303961 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0303777 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0297833 |
| NABP1 | nucleic acid binding protein 1 | 0.0295518 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0295314 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0291548 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.0286977 |
| CCNY | cyclin Y | 0.02855 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0284523 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0283555 |
| FERMT2 | fermitin family member 2 | 0.0283553 |
| MYO1E | myosin IE | 0.0283145 |
| TPM1 | tropomyosin 1 (alpha) | 0.0283059 |
| JAG1 | jagged 1 | 0.0279006 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0277567 |
| ITGB5 | integrin, beta 5 | 0.0277553 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0277415 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.027727 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0275178 |
| UGDH | UDP-glucose 6-dehydrogenase | 0.0273418 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.027185 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0270363 |
| FLNB | filamin B, beta | 0.0269283 |
| PLEC | plectin | 0.0268251 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.026624 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.0264318 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0263731 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0263292 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0262202 |
| SVIL | supervillin | 0.0261834 |
| VEGFA | vascular endothelial growth factor A | 0.0259861 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0258784 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0256936 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0256172 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.0254212 |
| TMSB10 | thymosin beta 10 | 0.0252303 |
| RPL3 | ribosomal protein L3 | 0.0251179 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0250997 |
| TXNRD1 | thioredoxin reductase 1 | 0.0250691 |
| CNKSR3 | CNKSR family member 3 | 0.025067 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.431374 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.117777 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.106979 |
| FNDC3B | fibronectin type III domain containing 3B | -0.09036 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0883303 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0865153 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.063849 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0586088 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0570863 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0548089 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0525023 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0465701 |
| RPS6 | ribosomal protein S6 | -0.0464151 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0462948 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0457199 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0432766 |
| WDR45B | WD repeat domain 45B | -0.0405549 |
| INSIG2 | insulin induced gene 2 | -0.0402165 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0400831 |
| CPE | carboxypeptidase E | -0.0384343 |
| GPC3 | glypican 3 | -0.0383393 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0382519 |
| GNAS | GNAS complex locus | -0.0380876 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -0.0371411 |
| RPLP0 | ribosomal protein, large, P0 | -0.0370066 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0364848 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0343141 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0335431 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0325519 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.032243 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0322035 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0319181 |
| AHSG | alpha-2-HS-glycoprotein | -0.0317405 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0311207 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0309687 |
| RPS8 | ribosomal protein S8 | -0.030709 |
| ENO1 | enolase 1, (alpha) | -0.0306794 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0306666 |
| FTL | ferritin, light polypeptide | -0.0298481 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0296542 |
| FAM13A | family with sequence similarity 13, member A | -0.0294901 |
| TMEM123 | transmembrane protein 123 | -0.0293286 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0282434 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0280549 |
| NUP58 | nucleoporin 58 | -0.027774 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.0272226 |
| PTMA | prothymosin, alpha | -0.0268414 |
| PEG3 | paternally expressed 3 | -0.0268253 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0257389 |
| FBXO42 | F-box protein 42 | -0.0256738 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0255384 |
| DTNA | dystrobrevin, alpha | -0.0252981 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0250867 |
| CP | ceruloplasmin (ferroxidase) | -0.0249462 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0248772 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0247035 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0246578 |
| TMEM51 | transmembrane protein 51 | -0.0246145 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0243656 |
| GOLGA4 | golgin A4 | -0.0239212 |
| TPM4 | tropomyosin 4 | -0.02368 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0236785 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0230828 |
| ZNF292 | zinc finger protein 292 | -0.0228531 |
| CANX | calnexin | -0.0228186 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.022646 |
| FAM117B | family with sequence similarity 117, member B | -0.0226136 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0224471 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0223613 |
| LYZ | lysozyme | -0.021849 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0218451 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.02183 |
| GK | glycerol kinase | -0.0217809 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0216787 |
| MYO1B | myosin IB | -0.0215237 |
| SDC4 | syndecan 4 | -0.0214996 |
| GDF15 | growth differentiation factor 15 | -0.0214646 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0212746 |
| RYBP | RING1 and YY1 binding protein | -0.0208948 |
| PDE8A | phosphodiesterase 8A | -0.0207659 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0207138 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.020532 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0202962 |
| PLIN2 | perilipin 2 | -0.0202494 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0199121 |
| RIOK3 | RIO kinase 3 | -0.0197538 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0197481 |
| PGK1 | phosphoglycerate kinase 1 | -0.0197407 |
| FAM162A | family with sequence similarity 162, member A | -0.0197272 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0196086 |
| RPL35A | ribosomal protein L35a | -0.0195845 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0195314 |
| ADM | adrenomedullin | -0.0195212 |
| HELZ | helicase with zinc finger | -0.0195199 |
| SNX9 | sorting nexin 9 | -0.0194861 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0193966 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.019393 |
| RPS13 | ribosomal protein S13 | -0.0193766 |
| RPL34 | ribosomal protein L34 | -0.0192009 |
| RLF | rearranged L-myc fusion | -0.0190081 |
