| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rimonabant perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rimonabant_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.26997 |
| LMO7 | LIM domain 7 | 0.248748 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.126734 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.114415 |
| FNDC3B | fibronectin type III domain containing 3B | 0.105334 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.101051 |
| PLEC | plectin | 0.100494 |
| HYOU1 | hypoxia up-regulated 1 | 0.0871978 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0753666 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.075213 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.074002 |
| MYOF | myoferlin | 0.0668609 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0660774 |
| KLHL29 | kelch-like family member 29 | 0.065204 |
| NDRG1 | N-myc downstream regulated 1 | 0.0628212 |
| CAPN8 | calpain 8 | 0.0608642 |
| ATXN1 | ataxin 1 | 0.0598597 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0592977 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0576396 |
| TXNRD1 | thioredoxin reductase 1 | 0.0575554 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.055887 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.054767 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.054311 |
| TJP1 | tight junction protein 1 | 0.0532144 |
| CMIP | c-Maf inducing protein | 0.0517984 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0508785 |
| SNX9 | sorting nexin 9 | 0.0503947 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0498057 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0470159 |
| FLNB | filamin B, beta | 0.046102 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0445335 |
| GOLGB1 | golgin B1 | 0.0440726 |
| DSPP | dentin sialophosphoprotein | 0.0439815 |
| CLTC | clathrin, heavy chain (Hc) | 0.043622 |
| HDLBP | high density lipoprotein binding protein | 0.0430537 |
| EZR | ezrin | 0.0421318 |
| AHNAK | AHNAK nucleoprotein | 0.0413625 |
| HM13 | histocompatibility (minor) 13 | 0.0404963 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0398879 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0397647 |
| EXT1 | exostosin glycosyltransferase 1 | 0.038889 |
| ANKRD11 | ankyrin repeat domain 11 | 0.038076 |
| FBXO11 | F-box protein 11 | 0.0379501 |
| VMP1 | vacuole membrane protein 1 | 0.037768 |
| SDCBP2 | syndecan binding protein (syntenin) 2 | 0.0376582 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0376329 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0370258 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0369155 |
| TES | testin LIM domain protein | 0.0365374 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0363715 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0363 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0361482 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0360152 |
| SEPTIN9 | septin 9 | 0.0356476 |
| GDA | guanine deaminase | 0.0354169 |
| FLNA | filamin A, alpha | 0.0349539 |
| HKDC1 | hexokinase domain containing 1 | 0.0344869 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0342025 |
| LAMB3 | laminin, beta 3 | 0.0339802 |
| ARCN1 | archain 1 | 0.0337174 |
| MYO1E | myosin IE | 0.0336423 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0335281 |
| KRT18 | keratin 18, type I | 0.0335108 |
| SMAD3 | SMAD family member 3 | 0.0331233 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0327468 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) | 0.0327419 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0323884 |
| USO1 | USO1 vesicle transport factor | 0.032055 |
| COPA | coatomer protein complex, subunit alpha | 0.031919 |
| INTS6 | integrator complex subunit 6 | 0.0316079 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0315326 |
| OXSR1 | oxidative stress responsive 1 | 0.0315324 |
| GOLGA4 | golgin A4 | 0.0311979 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0310177 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0309343 |
| BCL2L1 | BCL2-like 1 | 0.0306966 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0302723 |
| FNIP1 | folliculin interacting protein 1 | 0.03015 |
| LAMA4 | laminin, alpha 4 | 0.0297505 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 0.0291733 |
| ANXA2 | annexin A2 | 0.0288999 |
| MYO5B | myosin VB | 0.0281019 |
| FAT1 | FAT atypical cadherin 1 | 0.0278778 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0278227 |
| SPAG9 | sperm associated antigen 9 | 0.0275912 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.027424 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0271307 |
| CADPS2 | Ca++-dependent secretion activator 2 | 0.0267075 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0266988 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0265946 |
| COG6 | component of oligomeric golgi complex 6 | 0.0262506 |
| MED13 | mediator complex subunit 13 | 0.0261688 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.026116 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0258824 |
| ITGA6 | integrin, alpha 6 | 0.025836 |
| SETX | senataxin | 0.0257018 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0256413 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0253274 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | 0.0252726 |
| POF1B | premature ovarian failure, 1B | 0.0249265 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.116016 |
| NPSR1 | neuropeptide S receptor 1 | -0.110857 |
| B2M | beta-2-microglobulin | -0.0808216 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0661107 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0604249 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.059726 |
| RPL23 | ribosomal protein L23 | -0.0537703 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0511147 |
| RPS6 | ribosomal protein S6 | -0.0495515 |
| RPS3 | ribosomal protein S3 | -0.0459466 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0406533 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.040035 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0392696 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0388481 |
| FTL | ferritin, light polypeptide | -0.0350451 |
| HLA-B | major histocompatibility complex, class I, B | -0.0336454 |
| RPL11 | ribosomal protein L11 | -0.0335099 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0328646 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0327727 |
| RPL26 | ribosomal protein L26 | -0.0319532 |
| MKI67 | marker of proliferation Ki-67 | -0.0311297 |
| RPS12 | ribosomal protein S12 | -0.0306567 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0304948 |
| RPL37A | ribosomal protein L37a | -0.0298407 |
| ANLN | anillin, actin binding protein | -0.0296534 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0287024 |
| AGR3 | anterior gradient 3 | -0.0275431 |
| RAD51B | RAD51 paralog B | -0.0275405 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0263173 |
| THOC2 | THO complex 2 | -0.0260985 |
| RPS24 | ribosomal protein S24 | -0.0260238 |
| MECOM | MDS1 and EVI1 complex locus | -0.0258133 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0257973 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.025637 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0255191 |
| CDK6 | cyclin-dependent kinase 6 | -0.0254717 |
| LCN2 | lipocalin 2 | -0.0253969 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0253386 |
| RRM2 | ribonucleotide reductase M2 | -0.025234 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0246733 |
| RPS19 | ribosomal protein S19 | -0.0245985 |
| RPL9 | ribosomal protein L9 | -0.024375 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0242751 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0240413 |
| FANCI | Fanconi anemia, complementation group I | -0.0232535 |
| DEK | DEK proto-oncogene | -0.0231582 |
| RPL31 | ribosomal protein L31 | -0.022744 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0226744 |
| DIAPH3 | diaphanous-related formin 3 | -0.0225248 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0224942 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0224435 |
| HLA-A | major histocompatibility complex, class I, A | -0.0222449 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.0219885 |
| CD2AP | CD2-associated protein | -0.0216499 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | -0.0215701 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | -0.0212855 |
| MEIS2 | Meis homeobox 2 | -0.0207988 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0207817 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0207781 |
| COX6C | cytochrome c oxidase subunit VIc | -0.0205913 |
| RPS21 | ribosomal protein S21 | -0.0204176 |
| S100A10 | S100 calcium binding protein A10 | -0.0202389 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0201573 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | -0.0201126 |
| RPL18 | ribosomal protein L18 | -0.019964 |
| S100P | S100 calcium binding protein P | -0.019886 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.019664 |
| RPS17 | ribosomal protein S17 | -0.0196075 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0194636 |
| CBX3 | chromobox homolog 3 | -0.019417 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0188732 |
| RPL36A | ribosomal protein L36a | -0.0188536 |
| SMC1A | structural maintenance of chromosomes 1A | -0.0188401 |
| NFIA | nuclear factor I/A | -0.0182426 |
| SET | SET nuclear proto-oncogene | -0.0181889 |
| SRPK2 | SRSF protein kinase 2 | -0.0178264 |
| RPL35 | ribosomal protein L35 | -0.017763 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0177395 |
| TFRC | transferrin receptor | -0.0174408 |
| RPL19 | ribosomal protein L19 | -0.0173427 |
| DSTN | destrin (actin depolymerizing factor) | -0.0172973 |
| PTMA | prothymosin, alpha | -0.0171878 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0171565 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0167399 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0166506 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | -0.0165499 |
| GOLM1 | golgi membrane protein 1 | -0.0165174 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0164875 |
| RPS2 | ribosomal protein S2 | -0.0164204 |
| RBM25 | RNA binding motif protein 25 | -0.0163229 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0163156 |
| YAP1 | Yes-associated protein 1 | -0.0162621 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0162519 |
| RPL27 | ribosomal protein L27 | -0.0161925 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0161091 |
| RPS25 | ribosomal protein S25 | -0.0159585 |
| NXN | nucleoredoxin | -0.0159566 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0159533 |
| ADD3 | adducin 3 (gamma) | -0.0155798 |
| ETV6 | ets variant 6 | -0.0154076 |
