| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rimonabant perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rimonabant_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SMAD3 | SMAD family member 3 | 0.0952993 |
| GLCCI1 | glucocorticoid induced 1 | 0.088017 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0772629 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0759127 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0632713 |
| KSR1 | kinase suppressor of ras 1 | 0.0602132 |
| TGM2 | transglutaminase 2 | 0.0600867 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0573223 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0554484 |
| NRP1 | neuropilin 1 | 0.0551721 |
| MYO10 | myosin X | 0.0523481 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0516567 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0492569 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0468327 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0462727 |
| PCBP2 | poly(rC) binding protein 2 | 0.0456211 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0446394 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0439681 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.04318 |
| STK38L | serine/threonine kinase 38 like | 0.0426977 |
| NTN4 | netrin 4 | 0.0424574 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0422174 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0419778 |
| RAD51B | RAD51 paralog B | 0.0393794 |
| ECE1 | endothelin converting enzyme 1 | 0.0387653 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0384324 |
| DST | dystonin | 0.0382996 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0373385 |
| HMGA2 | high mobility group AT-hook 2 | 0.0371304 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0357583 |
| FAM20C | family with sequence similarity 20, member C | 0.034825 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.034719 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0344924 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0337576 |
| NDRG1 | N-myc downstream regulated 1 | 0.0331836 |
| EFNA5 | ephrin-A5 | 0.0325604 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0307339 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0297261 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.029648 |
| ETV6 | ets variant 6 | 0.029648 |
| EGFR | epidermal growth factor receptor | 0.029165 |
| POTEF | POTE ankyrin domain family, member F | 0.0290063 |
| NAV1 | neuron navigator 1 | 0.0289575 |
| IFI44L | interferon-induced protein 44-like | 0.0288441 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0287419 |
| PRELID2 | PRELI domain containing 2 | 0.0285791 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0281933 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0276826 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0272238 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0271154 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0265461 |
| VMP1 | vacuole membrane protein 1 | 0.0260471 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0258413 |
| ITGAV | integrin, alpha V | 0.0255835 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0253857 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.0251554 |
| KYNU | kynureninase | 0.0251249 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0249907 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.024862 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0245426 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.024419 |
| SEPTIN9 | septin 9 | 0.0239271 |
| MT2A | metallothionein 2A | 0.0238826 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0235782 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0233666 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.022936 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0227556 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0225938 |
| ADD3 | adducin 3 (gamma) | 0.0223003 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0222403 |
| CDK6 | cyclin-dependent kinase 6 | 0.0216984 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0216617 |
| CEP250 | centrosomal protein 250kDa | 0.0216563 |
| LOXL2 | lysyl oxidase-like 2 | 0.0216461 |
| PLEC | plectin | 0.0216419 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0215548 |
| ATXN1 | ataxin 1 | 0.0209939 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0206231 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0205417 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0205397 |
| VEGFA | vascular endothelial growth factor A | 0.0203254 |
| GLIS3 | GLIS family zinc finger 3 | 0.0202152 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | 0.0201221 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.0196516 |
| FHL2 | four and a half LIM domains 2 | 0.0195392 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.0195181 |
| ADAR | adenosine deaminase, RNA-specific | 0.0193429 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0192735 |
| SIK3 | SIK family kinase 3 | 0.0190712 |
| ANGPTL4 | angiopoietin-like 4 | 0.0190199 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0187992 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0186931 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | 0.0186215 |
| PRKCA | protein kinase C, alpha | 0.018331 |
| RNF213 | ring finger protein 213 | 0.0183096 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0182227 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0181614 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0181534 |
| INTS6 | integrator complex subunit 6 | 0.0181334 |
| MX1 | MX dynamin-like GTPase 1 | 0.0181255 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.1863 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.149186 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.132572 |
| VIM | vimentin | -0.120354 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.111434 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0780181 |
| PTMA | prothymosin, alpha | -0.067425 |
| TMSB10 | thymosin beta 10 | -0.0651351 |
| STC1 | stanniocalcin 1 | -0.0646283 |
| GOLGA4 | golgin A4 | -0.0634644 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0616201 |
| RPLP1 | ribosomal protein, large, P1 | -0.0574266 |
| IER3 | immediate early response 3 | -0.0574259 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0558253 |
| S100A6 | S100 calcium binding protein A6 | -0.053158 |
| MEF2A | myocyte enhancer factor 2A | -0.0519193 |
| CALU | calumenin | -0.0499691 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0495834 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0479957 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0459416 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0435674 |
| TMEM165 | transmembrane protein 165 | -0.04351 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0427905 |
| RPL35A | ribosomal protein L35a | -0.0427066 |
| CANX | calnexin | -0.0408718 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0405313 |
| TMEM263 | transmembrane protein 263 | -0.0403953 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0402136 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0398702 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0395126 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0381193 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0381171 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0379886 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0361722 |
| COPA | coatomer protein complex, subunit alpha | -0.0360924 |
| RBM39 | RNA binding motif protein 39 | -0.0356405 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0349743 |
| CDH13 | cadherin 13 | -0.0337956 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0333979 |
| SEC24A | SEC24 family member A | -0.0328827 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0324991 |
| NGLY1 | N-glycanase 1 | -0.0318479 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.031512 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0313039 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0312858 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0312049 |
| RPLP0 | ribosomal protein, large, P0 | -0.0305976 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0302206 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0297505 |
| RPS29 | ribosomal protein S29 | -0.0295458 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0287635 |
| HM13 | histocompatibility (minor) 13 | -0.0287527 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0284573 |
| RPS24 | ribosomal protein S24 | -0.0283465 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0282998 |
| FAM107B | family with sequence similarity 107, member B | -0.0281166 |
| CALR | calreticulin | -0.0279899 |
| RPL34 | ribosomal protein L34 | -0.0278117 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0277737 |
| FAM13A | family with sequence similarity 13, member A | -0.0277099 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0276636 |
| USP3 | ubiquitin specific peptidase 3 | -0.0275745 |
| HDLBP | high density lipoprotein binding protein | -0.0274544 |
| TMSB4X | thymosin beta 4, X-linked | -0.0274492 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0271447 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0268735 |
| OGA | O-GlcNAcase | -0.0265896 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0263209 |
| RPL37 | ribosomal protein L37 | -0.0261508 |
| MTSS1 | metastasis suppressor 1 | -0.0261317 |
| CD109 | CD109 molecule | -0.0259725 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.025214 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.025177 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0250903 |
| RPS21 | ribosomal protein S21 | -0.0249915 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0246842 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0243216 |
| WDR45B | WD repeat domain 45B | -0.0240248 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0236076 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.023536 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0232191 |
| RLF | rearranged L-myc fusion | -0.0232091 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0228523 |
| SRP54 | signal recognition particle 54kDa | -0.0226991 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0226245 |
| RPL12 | ribosomal protein L12 | -0.0225959 |
| INSIG1 | insulin induced gene 1 | -0.0225901 |
| GNAS | GNAS complex locus | -0.022418 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.022398 |
| ARF4 | ADP-ribosylation factor 4 | -0.0223407 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0220406 |
| SNX9 | sorting nexin 9 | -0.0219759 |
| S100A10 | S100 calcium binding protein A10 | -0.0219099 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0218673 |
| IL1B | interleukin 1, beta | -0.0216123 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0215107 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0212773 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.021209 |
| POM121C | POM121 transmembrane nucleoporin C | -0.0211945 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.021159 |
