| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rimonabant perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rimonabant_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PM20D1 | peptidase M20 domain containing 1 | 0.246643 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.235481 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.112443 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.098953 |
| ACTG1 | actin gamma 1 | 0.0838372 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0808933 |
| WWOX | WW domain containing oxidoreductase | 0.0789956 |
| FTL | ferritin, light polypeptide | 0.0762615 |
| TMSB10 | thymosin beta 10 | 0.0750254 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.065132 |
| FLNA | filamin A, alpha | 0.0640803 |
| BICC1 | BicC family RNA binding protein 1 | 0.0625152 |
| NRG1 | neuregulin 1 | 0.0617161 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0606433 |
| TXNRD1 | thioredoxin reductase 1 | 0.0599812 |
| CMIP | c-Maf inducing protein | 0.0566312 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0539086 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0480603 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0474066 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0471052 |
| BMP6 | bone morphogenetic protein 6 | 0.0458735 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0454382 |
| RPS21 | ribosomal protein S21 | 0.0443606 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0428102 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0425671 |
| KYNU | kynureninase | 0.0410351 |
| GRAMD1B | GRAM domain containing 1B | 0.0402109 |
| GLIS3 | GLIS family zinc finger 3 | 0.0388021 |
| SMAD2 | SMAD family member 2 | 0.0361411 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.035433 |
| PFN1 | profilin 1 | 0.0348223 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0337223 |
| PDE8A | phosphodiesterase 8A | 0.033219 |
| MYOF | myoferlin | 0.0326903 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.031674 |
| FAM107B | family with sequence similarity 107, member B | 0.031634 |
| HMGA1 | high mobility group AT-hook 1 | 0.0312678 |
| RPS19 | ribosomal protein S19 | 0.0311079 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0311006 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0310162 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0303482 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0302145 |
| MRTFA | myocardin related transcription factor A | 0.0295185 |
| IGF2 | insulin-like growth factor 2 | 0.0290173 |
| PDE10A | phosphodiesterase 10A | 0.0286018 |
| USP3 | ubiquitin specific peptidase 3 | 0.0283828 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0283008 |
| LAMB1 | laminin, beta 1 | 0.0279824 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | 0.0279237 |
| ZNF277 | zinc finger protein 277 | 0.0278547 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0277939 |
| SRGN | serglycin | 0.027465 |
| ATP5F1E | ATP synthase F1 subunit epsilon | 0.0269651 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0265997 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0265602 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0263954 |
| EGR1 | early growth response 1 | 0.0262142 |
| TPI1 | triosephosphate isomerase 1 | 0.0262104 |
| FHIT | fragile histidine triad | 0.025802 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0257505 |
| ASPH | aspartate beta-hydroxylase | 0.0256477 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0256294 |
| RAD51B | RAD51 paralog B | 0.0252327 |
| RSPO3 | R-spondin 3 | 0.0252178 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0251935 |
| OSMR | oncostatin M receptor | 0.0250589 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0246554 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.024053 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0237959 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0235669 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0232993 |
| EPGN | epithelial mitogen | 0.023222 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0231607 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.022829 |
| ENAH | enabled homolog (Drosophila) | 0.0227178 |
| LAMA5 | laminin, alpha 5 | 0.0225674 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0224418 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.02201 |
| CNKSR3 | CNKSR family member 3 | 0.0219942 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.021694 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.021522 |
| ACACA | acetyl-CoA carboxylase alpha | 0.0212998 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0212601 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0210598 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0200148 |
| SERF2 | small EDRK-rich factor 2 | 0.0197254 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | 0.0196814 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0195858 |
| ATP11A | ATPase, class VI, type 11A | 0.0195779 |
| NTN4 | netrin 4 | 0.0195534 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0194643 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0193366 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.019131 |
| GPR39 | G protein-coupled receptor 39 | 0.0190897 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0189238 |
| PLS3 | plastin 3 | 0.0188407 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.0188283 |
| DST | dystonin | 0.0188017 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0186814 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0186761 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.18468 |
| VIM | vimentin | -0.117704 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0869379 |
| RPS27A | ribosomal protein S27a | -0.0790892 |
| COPA | coatomer protein complex, subunit alpha | -0.0710905 |
| UBC | ubiquitin C | -0.0706038 |
| PYGL | phosphorylase, glycogen, liver | -0.0688894 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0674442 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0662502 |
| PTMA | prothymosin, alpha | -0.0652182 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0651247 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0644987 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0622697 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0602539 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0600694 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0591298 |
| TPM3 | tropomyosin 3 | -0.0545218 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0542106 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0519525 |
| GLG1 | golgi glycoprotein 1 | -0.0518608 |
| KIF5B | kinesin family member 5B | -0.0502062 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0485419 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0482475 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0464784 |
| GOLGA4 | golgin A4 | -0.0463929 |
| ENO1 | enolase 1, (alpha) | -0.0436706 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0421246 |
| HLA-B | major histocompatibility complex, class I, B | -0.0420614 |
| HLA-A | major histocompatibility complex, class I, A | -0.0419956 |
| RSF1 | remodeling and spacing factor 1 | -0.0417195 |
| NOP58 | NOP58 ribonucleoprotein | -0.0417025 |
| CFDP1 | craniofacial development protein 1 | -0.040772 |
| TPM4 | tropomyosin 4 | -0.0402569 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0395949 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0392817 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0390988 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0390271 |
| APP | amyloid beta (A4) precursor protein | -0.0387683 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0386373 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0379807 |
| S100A6 | S100 calcium binding protein A6 | -0.0378677 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0378002 |
| SRP54 | signal recognition particle 54kDa | -0.0377422 |
| IL6 | interleukin 6 | -0.037038 |
| AHNAK | AHNAK nucleoprotein | -0.0370193 |
| YY1 | YY1 transcription factor | -0.0367622 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.036401 |
| IER3 | immediate early response 3 | -0.0360468 |
| HLA-E | major histocompatibility complex, class I, E | -0.0355738 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0353828 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0351757 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0341668 |
| GGNBP2 | gametogenetin binding protein 2 | -0.0341137 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.033936 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0336377 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0332878 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0331678 |
| MATR3 | matrin 3 | -0.0325427 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0322772 |
| RNF216 | ring finger protein 216 | -0.0322468 |
| SQSTM1 | sequestosome 1 | -0.0321017 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0320693 |
| RHOA | ras homolog family member A | -0.0319838 |
| SEPTIN7 | septin 7 | -0.0319396 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0318422 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.031616 |
| SBF2 | SET binding factor 2 | -0.0315311 |
| ARF4 | ADP-ribosylation factor 4 | -0.0311661 |
| CD99 | CD99 molecule | -0.0307924 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.030771 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.0307007 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0303991 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0300862 |
| DENND5B | DENN/MADD domain containing 5B | -0.0298645 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0296077 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.0295376 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0295143 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0294738 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0292367 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.0291801 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0290966 |
| NUMB | numb homolog (Drosophila) | -0.0290429 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | -0.0290178 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0289945 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0289921 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.0284965 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0284175 |
| CALR | calreticulin | -0.0283867 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0282459 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0282437 |
| CALU | calumenin | -0.0282404 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0282091 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0280537 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0279343 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | -0.027783 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0277679 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0276691 |
| RPS8 | ribosomal protein S8 | -0.0276633 |
| MED13 | mediator complex subunit 13 | -0.0276535 |
| NUP98 | nucleoporin 98kDa | -0.0275062 |
