| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rimonabant perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rimonabant_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.138621 |
| LAMC2 | laminin, gamma 2 | 0.129049 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.076393 |
| CMIP | c-Maf inducing protein | 0.0760979 |
| PDE10A | phosphodiesterase 10A | 0.0749986 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0739967 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0737798 |
| MT2A | metallothionein 2A | 0.0717842 |
| IGF2 | insulin-like growth factor 2 | 0.0705062 |
| EGFR | epidermal growth factor receptor | 0.0658048 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0652282 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0609124 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0592037 |
| NDRG1 | N-myc downstream regulated 1 | 0.0591926 |
| MCL1 | myeloid cell leukemia 1 | 0.0546927 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0530542 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0514872 |
| DST | dystonin | 0.0503272 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0499049 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0494712 |
| SETX | senataxin | 0.0494209 |
| TXNRD1 | thioredoxin reductase 1 | 0.0480224 |
| AK1 | adenylate kinase 1 | 0.0469988 |
| STAU2 | staufen double-stranded RNA binding protein 2 | 0.0462086 |
| EFNA5 | ephrin-A5 | 0.0461383 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0444966 |
| KIF5B | kinesin family member 5B | 0.044103 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0440288 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0439744 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0438433 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0438067 |
| RNF213 | ring finger protein 213 | 0.0436473 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0432987 |
| DUSP16 | dual specificity phosphatase 16 | 0.0432147 |
| SVIL | supervillin | 0.0411523 |
| KLF6 | Kruppel-like factor 6 | 0.0409893 |
| MEST | mesoderm specific transcript | 0.0408329 |
| PLEC | plectin | 0.040168 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.039972 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0396663 |
| R3HDM2 | R3H domain containing 2 | 0.039253 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0391787 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0391131 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.038914 |
| C3 | complement component 3 | 0.0387435 |
| FLNB | filamin B, beta | 0.038497 |
| GOLGB1 | golgin B1 | 0.0381284 |
| RAD51B | RAD51 paralog B | 0.0380986 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0378632 |
| LAMA4 | laminin, alpha 4 | 0.0378471 |
| SON | SON DNA binding protein | 0.037783 |
| FBXO11 | F-box protein 11 | 0.0377555 |
| NF1 | neurofibromin 1 | 0.0371996 |
| CDK19 | cyclin-dependent kinase 19 | 0.0369348 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 0.0354441 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0351988 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0349672 |
| RBM47 | RNA binding motif protein 47 | 0.0344705 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0336788 |
| JMJD1C | jumonji domain containing 1C | 0.033395 |
| RAB10 | RAB10, member RAS oncogene family | 0.0333324 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0330819 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0327561 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0326149 |
| CD2AP | CD2-associated protein | 0.0323535 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0321426 |
| TMCC3 | transmembrane and coiled-coil domain family 3 | 0.0315082 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0313945 |
| NBAS | neuroblastoma amplified sequence | 0.0312179 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0310332 |
| DCUN1D3 | DCN1, defective in cullin neddylation 1, domain containing 3 | 0.0307399 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0307336 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0304779 |
| PCM1 | pericentriolar material 1 | 0.0304195 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0302969 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | 0.0301383 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0300992 |
| PDLIM5 | PDZ and LIM domain 5 | 0.029938 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0297337 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0293967 |
| PHF14 | PHD finger protein 14 | 0.0292482 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.029248 |
| TUSC3 | tumor suppressor candidate 3 | 0.0290477 |
| AHNAK | AHNAK nucleoprotein | 0.0290199 |
| CYRIB | CYFIP related Rac1 interactor B | 0.0289023 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.028855 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.028833 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0286731 |
| GOLGA4 | golgin A4 | 0.0284758 |
| ZFHX3 | zinc finger homeobox 3 | 0.0284627 |
| CADM2 | cell adhesion molecule 2 | 0.0282871 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0277399 |
| PDE7A | phosphodiesterase 7A | 0.0274944 |
| AEBP2 | AE binding protein 2 | 0.0274712 |
| FAM13A | family with sequence similarity 13, member A | 0.0274162 |
| NPLOC4 | nuclear protein localization 4 homolog (S. cerevisiae) | 0.0273426 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0272713 |
| RPL8 | ribosomal protein L8 | 0.0272682 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.027099 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0270688 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.148935 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0980994 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0898345 |
| VIM | vimentin | -0.0831571 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0725628 |
| FTL | ferritin, light polypeptide | -0.0709632 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0683437 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0641135 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0631091 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0586922 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0582325 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0569644 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0564882 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0563794 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.055684 |
| RPL23 | ribosomal protein L23 | -0.0552179 |
| ANXA1 | annexin A1 | -0.0543807 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0541797 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.05401 |
| PTMA | prothymosin, alpha | -0.053763 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0526786 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0523831 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0502933 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0491961 |
| PHF21A | PHD finger protein 21A | -0.0487043 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0482006 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0473116 |
| MYO1E | myosin IE | -0.0469522 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.045706 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0448987 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0447949 |
| ATOSA | atos homolog A | -0.0447443 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0443288 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0442342 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0439243 |
| CUL3 | cullin 3 | -0.043884 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0438179 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0433525 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0431113 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0417592 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0412669 |
| ANXA2 | annexin A2 | -0.0410632 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.040488 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0403428 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0400595 |
| CANX | calnexin | -0.0400181 |
| PGK1 | phosphoglycerate kinase 1 | -0.0396942 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0393183 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0391924 |
| YBX3 | Y box binding protein 3 | -0.0390404 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.038494 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0382953 |
| IWS1 | IWS1 homolog (S. cerevisiae) | -0.0381588 |
| MYO10 | myosin X | -0.0380905 |
| CCDC6 | coiled-coil domain containing 6 | -0.0376776 |
| TMEM123 | transmembrane protein 123 | -0.0376421 |
| CUL1 | cullin 1 | -0.0371717 |
| ATXN1 | ataxin 1 | -0.0362946 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | -0.0358079 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0355386 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0350352 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0349609 |
| SNX9 | sorting nexin 9 | -0.0345967 |
| MYO5B | myosin VB | -0.0345942 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.034526 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0343929 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0341351 |
| NBEAL1 | neurobeachin-like 1 | -0.0339963 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0339642 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0336 |
| SLMAP | sarcolemma associated protein | -0.033174 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | -0.0330638 |
| SQSTM1 | sequestosome 1 | -0.0330063 |
| TMSB10 | thymosin beta 10 | -0.0329429 |
| H3-3B | H3.3 histone B | -0.032832 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0326901 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0323272 |
| SRPK2 | SRSF protein kinase 2 | -0.0323117 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0321599 |
| SPAG9 | sperm associated antigen 9 | -0.0321387 |
| LAMB1 | laminin, beta 1 | -0.0321078 |
| CLTC | clathrin, heavy chain (Hc) | -0.0320726 |
| HMGA1 | high mobility group AT-hook 1 | -0.0320033 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0318626 |
| HLA-B | major histocompatibility complex, class I, B | -0.0317865 |
| S100A9 | S100 calcium binding protein A9 | -0.0310705 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.030978 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0308701 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0308062 |
| RHEB | Ras homolog enriched in brain | -0.0306529 |
| RUNX1 | runt-related transcription factor 1 | -0.030651 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0303377 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | -0.0302835 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0302706 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.0302416 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0301157 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0299672 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0299566 |
| CALD1 | caldesmon 1 | -0.0298101 |
| ATP11B | ATPase, class VI, type 11B | -0.0293739 |
