| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rimonabant perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rimonabant_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MCL1 | myeloid cell leukemia 1 | 0.126488 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.102175 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0990349 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.08556 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0850052 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0834314 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0804469 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0733304 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0725582 |
| TXNRD1 | thioredoxin reductase 1 | 0.0717541 |
| GRAMD1B | GRAM domain containing 1B | 0.0699118 |
| ATXN1 | ataxin 1 | 0.0658718 |
| INTS6 | integrator complex subunit 6 | 0.0620072 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0607376 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0595214 |
| HOMER1 | homer scaffolding protein 1 | 0.0573741 |
| YBX3 | Y box binding protein 3 | 0.0543926 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0541533 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0537961 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0523992 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0521559 |
| EGR1 | early growth response 1 | 0.0520588 |
| FLNA | filamin A, alpha | 0.0512574 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0510024 |
| RPL3 | ribosomal protein L3 | 0.050783 |
| POTEF | POTE ankyrin domain family, member F | 0.0501789 |
| AEBP2 | AE binding protein 2 | 0.0501264 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0499979 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0479194 |
| ACTG1 | actin gamma 1 | 0.0465579 |
| BRD2 | bromodomain containing 2 | 0.0449132 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0443395 |
| PRELID2 | PRELI domain containing 2 | 0.0438701 |
| WWOX | WW domain containing oxidoreductase | 0.0422207 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0420208 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0417058 |
| TMSB10 | thymosin beta 10 | 0.0412112 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0411164 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0408873 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0407694 |
| ATP11A | ATPase, class VI, type 11A | 0.0404975 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0402128 |
| CAPRIN2 | caprin family member 2 | 0.0396528 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0392147 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0385116 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.0379889 |
| TPI1 | triosephosphate isomerase 1 | 0.0367413 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0352975 |
| YAP1 | Yes-associated protein 1 | 0.0352928 |
| PDE10A | phosphodiesterase 10A | 0.0352298 |
| PLEC | plectin | 0.0351391 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0343146 |
| TRIM59 | tripartite motif containing 59 | 0.0341633 |
| HMOX1 | heme oxygenase 1 | 0.0340271 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0337033 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0333183 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0332559 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0332305 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.033199 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0326091 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0323833 |
| NABP1 | nucleic acid binding protein 1 | 0.0315535 |
| SRSF3 | serine/arginine-rich splicing factor 3 | 0.0315485 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0307322 |
| SVIL | supervillin | 0.0298868 |
| ADAR | adenosine deaminase, RNA-specific | 0.0292189 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0285393 |
| RAD51B | RAD51 paralog B | 0.0280843 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0280042 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0275929 |
| RNF145 | ring finger protein 145 | 0.0275272 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0271932 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | 0.0271259 |
| WNT9A | wingless-type MMTV integration site family, member 9A | 0.0268466 |
| FMNL2 | formin-like 2 | 0.0264176 |
| MEF2D | myocyte enhancer factor 2D | 0.0263663 |
| PFN1 | profilin 1 | 0.0263493 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0261301 |
| RRM2 | ribonucleotide reductase M2 | 0.026052 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.0258217 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0257119 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0256701 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.025436 |
| RCC1 | regulator of chromosome condensation 1 | 0.0254298 |
| CCDC200 | coiled-coil domain containing 200 | 0.025392 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0253113 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0250884 |
| DCLK1 | doublecortin-like kinase 1 | 0.0248725 |
| ACTN1 | actinin, alpha 1 | 0.0248688 |
| VCL | vinculin | 0.0246124 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0243866 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.0243737 |
| CDK17 | cyclin-dependent kinase 17 | 0.0243491 |
| ALG13 | ALG13, UDP-N-acetylglucosaminyltransferase subunit | 0.0243234 |
| PRRC2A | proline-rich coiled-coil 2A | 0.024156 |
| RASAL2 | RAS protein activator like 2 | 0.0240045 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.0238972 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0238726 |
| IGF2 | insulin-like growth factor 2 | 0.0238477 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0237916 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0931805 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0713457 |
| VIM | vimentin | -0.0607821 |
| PTMA | prothymosin, alpha | -0.0583382 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0567506 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0519467 |
| GOLGA4 | golgin A4 | -0.0496869 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0482987 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.046168 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0450861 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.041427 |
| RPL35A | ribosomal protein L35a | -0.0384361 |
| PGK1 | phosphoglycerate kinase 1 | -0.0377881 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0377658 |
| CANX | calnexin | -0.0373353 |
| CALU | calumenin | -0.0364573 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0360164 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0359873 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0355742 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0353261 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0351704 |
| CLDN1 | claudin 1 | -0.0350389 |
| TLK1 | tousled-like kinase 1 | -0.0346568 |
| RPLP0 | ribosomal protein, large, P0 | -0.0344331 |
| RPLP1 | ribosomal protein, large, P1 | -0.0340614 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0339551 |
| RPL26 | ribosomal protein L26 | -0.0336289 |
| BBX | bobby sox homolog (Drosophila) | -0.0333561 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0330028 |
| RPS27A | ribosomal protein S27a | -0.0327868 |
| CAVIN1 | caveolae associated protein 1 | -0.0326501 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0314083 |
| RPS8 | ribosomal protein S8 | -0.0310675 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0309659 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0304592 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0302619 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0300258 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0296922 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.029439 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | -0.0293927 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0291691 |
| MATR3 | matrin 3 | -0.0291582 |
| RLF | rearranged L-myc fusion | -0.0291222 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) | -0.028652 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0285728 |
| ZFR | zinc finger RNA binding protein | -0.0285182 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.028504 |
| PHIP | pleckstrin homology domain interacting protein | -0.0281831 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0281793 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0281425 |
| TMEM165 | transmembrane protein 165 | -0.0279429 |
| EGFR | epidermal growth factor receptor | -0.02776 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0273697 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.027238 |
| SRP72 | signal recognition particle 72kDa | -0.0271564 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0269551 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0268904 |
| HM13 | histocompatibility (minor) 13 | -0.0268334 |
| RPL4 | ribosomal protein L4 | -0.0267612 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0266182 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0265743 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.026412 |
| GLG1 | golgi glycoprotein 1 | -0.0263399 |
| OGA | O-GlcNAcase | -0.0262833 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0262487 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0258496 |
| RPL38 | ribosomal protein L38 | -0.0258176 |
| ARF4 | ADP-ribosylation factor 4 | -0.0257958 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0251853 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0251035 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0249306 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0248516 |
| RPL39 | ribosomal protein L39 | -0.0247662 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | -0.0246396 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0241936 |
| RTN4 | reticulon 4 | -0.0241738 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0241603 |
| XPO1 | exportin 1 | -0.0240415 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0240215 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0238166 |
| RPS6 | ribosomal protein S6 | -0.0238101 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0235076 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0234822 |
| RPL34 | ribosomal protein L34 | -0.0234229 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0233603 |
| DEK | DEK proto-oncogene | -0.0232837 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0230796 |
| RPL30 | ribosomal protein L30 | -0.0229014 |
| DARS1 | aspartyl-tRNA synthetase 1 | -0.0228396 |
| WDR45B | WD repeat domain 45B | -0.0226726 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0226339 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0226076 |
| GOLT1B | golgi transport 1B | -0.0225617 |
| FTL | ferritin, light polypeptide | -0.0225386 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0222658 |
| S100A6 | S100 calcium binding protein A6 | -0.0221504 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.022145 |
| ZNF292 | zinc finger protein 292 | -0.0218734 |
| MYO6 | myosin VI | -0.0217965 |
| RPS24 | ribosomal protein S24 | -0.0215992 |
