| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rimonabant perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rimonabant_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.238177 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.126381 |
| PLEC | plectin | 0.0969513 |
| ACTG1 | actin gamma 1 | 0.073754 |
| LAMB3 | laminin, beta 3 | 0.0620125 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0615842 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0588702 |
| POTEF | POTE ankyrin domain family, member F | 0.04803 |
| MSN | moesin | 0.0421383 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0408157 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0386716 |
| DSPP | dentin sialophosphoprotein | 0.0365186 |
| PGBD5 | piggyBac transposable element derived 5 | 0.0347637 |
| JUP | junction plakoglobin | 0.0344626 |
| FLNA | filamin A, alpha | 0.0331015 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0320712 |
| MYO5B | myosin VB | 0.0318872 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.031267 |
| RPL3 | ribosomal protein L3 | 0.0309078 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.02927 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0291352 |
| EGFR | epidermal growth factor receptor | 0.0288117 |
| VEGFA | vascular endothelial growth factor A | 0.0283495 |
| SEPTIN9 | septin 9 | 0.0273804 |
| VGLL3 | vestigial-like family member 3 | 0.0262162 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0258686 |
| MKI67 | marker of proliferation Ki-67 | 0.0258339 |
| MT2A | metallothionein 2A | 0.0253197 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0249477 |
| MAP1B | microtubule-associated protein 1B | 0.024825 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0248024 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0247109 |
| KRT7 | keratin 7, type II | 0.0239596 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0237099 |
| FHIT | fragile histidine triad | 0.0232975 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0230656 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0230604 |
| CD44 | CD44 molecule (Indian blood group) | 0.0222146 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0220542 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0217613 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0216102 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0213721 |
| NDRG1 | N-myc downstream regulated 1 | 0.0205532 |
| CLDN4 | claudin 4 | 0.0204316 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.0199825 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.019978 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.019821 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | 0.0197966 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0197291 |
| BCL2L1 | BCL2-like 1 | 0.0197223 |
| ANO6 | anoctamin 6 | 0.0195267 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0188708 |
| G0S2 | G0/G1 switch 2 | 0.01854 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0184047 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0183115 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0182321 |
| NTN4 | netrin 4 | 0.0182266 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0177673 |
| EFNA5 | ephrin-A5 | 0.0176624 |
| CAB39 | calcium binding protein 39 | 0.0173904 |
| ANXA11 | annexin A11 | 0.0173772 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0171074 |
| SH3RF2 | SH3 domain containing ring finger 2 | 0.0167338 |
| GPX4 | glutathione peroxidase 4 | 0.016723 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0164485 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0162701 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0157545 |
| ANXA1 | annexin A1 | 0.0157438 |
| OCLN | occludin | 0.0156864 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0155925 |
| TAPBP | TAP binding protein (tapasin) | 0.0155373 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.015431 |
| ZNF185 | zinc finger protein 185 (LIM domain) | 0.0153546 |
| DUSP10 | dual specificity phosphatase 10 | 0.0151587 |
| RPS12 | ribosomal protein S12 | 0.0151369 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.0149902 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0148675 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0148103 |
| IFI44L | interferon-induced protein 44-like | 0.0148067 |
| TJP2 | tight junction protein 2 | 0.0146856 |
| PRKCA | protein kinase C, alpha | 0.0146504 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0142978 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0142326 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0141971 |
| RNF213 | ring finger protein 213 | 0.0139371 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.0137434 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0135917 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0133784 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0132742 |
| SVIL | supervillin | 0.0132514 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0131811 |
| RASAL2 | RAS protein activator like 2 | 0.0130656 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0130626 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0128132 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0127635 |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) | 0.0127306 |
| TTC9 | tetratricopeptide repeat domain 9 | 0.0126555 |
| CDH15 | cadherin 15, type 1, M-cadherin (myotubule) | 0.0126517 |
| ARHGAP20 | Rho GTPase activating protein 20 | 0.0123757 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0122881 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.302552 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.257623 |
| PTMA | prothymosin, alpha | -0.165146 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0870127 |
| FAM13A | family with sequence similarity 13, member A | -0.0843438 |
| CANX | calnexin | -0.0810246 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0761359 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0744299 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0712932 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0706385 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0698887 |
| TMSB4X | thymosin beta 4, X-linked | -0.0694057 |
| SLC38A1 | solute carrier family 38, member 1 | -0.068471 |
| ASPH | aspartate beta-hydroxylase | -0.0684703 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0680979 |
| FN1 | fibronectin 1 | -0.0675498 |
| S100A6 | S100 calcium binding protein A6 | -0.0667648 |
| RPL35A | ribosomal protein L35a | -0.0649783 |
| RBM39 | RNA binding motif protein 39 | -0.064191 |
| GOLGA4 | golgin A4 | -0.0614904 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0596234 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0594533 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0556853 |
| ZNF292 | zinc finger protein 292 | -0.0548709 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0542947 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0539828 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0536274 |
| RLF | rearranged L-myc fusion | -0.0533366 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0511688 |
| SPAG9 | sperm associated antigen 9 | -0.0503819 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.048767 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0487488 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0484323 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0479776 |
| RPL34 | ribosomal protein L34 | -0.0470855 |
| PTK2 | protein tyrosine kinase 2 | -0.046844 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0467367 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0442257 |
| HMGB2 | high mobility group box 2 | -0.0440748 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0438053 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0435144 |
| GNAS | GNAS complex locus | -0.0433792 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0433084 |
| ANXA2 | annexin A2 | -0.0421387 |
| TOP1 | topoisomerase (DNA) I | -0.0417946 |
| RPLP1 | ribosomal protein, large, P1 | -0.041743 |
| MATR3 | matrin 3 | -0.0402767 |
| RBM25 | RNA binding motif protein 25 | -0.0402223 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0397942 |
| TFG | TRK-fused gene | -0.0394296 |
| ZNF207 | zinc finger protein 207 | -0.0390015 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0388444 |
| PGK1 | phosphoglycerate kinase 1 | -0.0384968 |
| PARD3 | par-3 family cell polarity regulator | -0.0383991 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0381732 |
| TMEM263 | transmembrane protein 263 | -0.037725 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0377094 |
| CDC73 | cell division cycle 73 | -0.0376284 |
| RPLP0 | ribosomal protein, large, P0 | -0.0374572 |
| COPA | coatomer protein complex, subunit alpha | -0.0370228 |
| CALU | calumenin | -0.0367698 |
| RPS6 | ribosomal protein S6 | -0.0366635 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0366467 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0366429 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0365403 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0360984 |
| RHEB | Ras homolog enriched in brain | -0.0359759 |
| HELZ | helicase with zinc finger | -0.0356967 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0356123 |
| USP3 | ubiquitin specific peptidase 3 | -0.0355907 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0354355 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0345741 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0344924 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.034255 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0340946 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0335431 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0335196 |
| RPS24 | ribosomal protein S24 | -0.0334119 |
| ARF1 | ADP-ribosylation factor 1 | -0.033375 |
| CD2AP | CD2-associated protein | -0.0331868 |
| RPS8 | ribosomal protein S8 | -0.0328129 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.032622 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0326141 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0323742 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.031979 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0317247 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.031616 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0308104 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0306952 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0306096 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0305175 |
| RNF145 | ring finger protein 145 | -0.0304756 |
| TMSB10 | thymosin beta 10 | -0.0300475 |
| SLMAP | sarcolemma associated protein | -0.0298019 |
| PUM1 | pumilio RNA-binding family member 1 | -0.0297134 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0296681 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0293719 |
| PAPOLA | poly(A) polymerase alpha | -0.0288071 |
| TFRC | transferrin receptor | -0.0287645 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0286235 |
