| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rimonabant perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rimonabant_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HDAC9 | histone deacetylase 9 | 0.110309 |
| ANK2 | ankyrin 2, neuronal | 0.0767134 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0740307 |
| NHSL1 | NHS-like 1 | 0.0702946 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0653948 |
| COL5A2 | collagen, type V, alpha 2 | 0.0636895 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.0602244 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0588962 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0580861 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0568609 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0564581 |
| MED13L | mediator complex subunit 13-like | 0.0560351 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0553666 |
| PHIP | pleckstrin homology domain interacting protein | 0.0535626 |
| ITGAV | integrin, alpha V | 0.0524956 |
| JUN | jun proto-oncogene | 0.0472493 |
| ANKRD33B | ankyrin repeat domain 33B | 0.045208 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0447393 |
| RBM20 | RNA binding motif protein 20 | 0.04437 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0435115 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0435064 |
| PCDH18 | protocadherin 18 | 0.0428281 |
| POTEF | POTE ankyrin domain family, member F | 0.041925 |
| PHF21A | PHD finger protein 21A | 0.0410068 |
| FAM171B | family with sequence similarity 171, member B | 0.0385926 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.038457 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0367126 |
| BRD2 | bromodomain containing 2 | 0.0361761 |
| HECTD4 | HECT domain containing E3 ubiquitin protein ligase 4 | 0.0355416 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0352972 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0349662 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0347004 |
| SERTAD2 | SERTA domain containing 2 | 0.0346277 |
| PLPP1 | phospholipid phosphatase 1 | 0.0345139 |
| LRRC4C | leucine rich repeat containing 4C | 0.0343887 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0339987 |
| NCOA2 | nuclear receptor coactivator 2 | 0.0339957 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0337501 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0335797 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0333708 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0333084 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0327167 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0324279 |
| RASAL2 | RAS protein activator like 2 | 0.0323821 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0323203 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 0.0321226 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0320271 |
| NFIB | nuclear factor I/B | 0.0319588 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | 0.0315601 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.0315167 |
| GOLIM4 | golgi integral membrane protein 4 | 0.0311692 |
| LAMA2 | laminin, alpha 2 | 0.0309088 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0306259 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0305596 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0305103 |
| EGFR | epidermal growth factor receptor | 0.0302604 |
| LYST | lysosomal trafficking regulator | 0.0301293 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0300075 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0296824 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.029308 |
| ZFP36 | ZFP36 ring finger protein | 0.0291546 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0289062 |
| GPHN | gephyrin | 0.0287353 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0282374 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0281988 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.028193 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | 0.0281911 |
| TOX | thymocyte selection-associated high mobility group box | 0.0281764 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0280965 |
| TPM3 | tropomyosin 3 | 0.0279317 |
| KIF21A | kinesin family member 21A | 0.027814 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | 0.027801 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0277129 |
| FKBP5 | FK506 binding protein 5 | 0.0275241 |
| SNX3 | sorting nexin 3 | 0.0274025 |
| UBAP2 | ubiquitin associated protein 2 | 0.027077 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 0.0267399 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0267181 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0266038 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0264239 |
| SCFD1 | sec1 family domain containing 1 | 0.0264131 |
| CCNYL1 | cyclin Y-like 1 | 0.0261705 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0261058 |
| PDE8A | phosphodiesterase 8A | 0.02588 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.0255606 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0255188 |
| TMF1 | TATA element modulatory factor 1 | 0.0254998 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0251754 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0250867 |
| GAB2 | GRB2-associated binding protein 2 | 0.0250698 |
| KIF1B | kinesin family member 1B | 0.025064 |
| ZNF217 | zinc finger protein 217 | 0.0250479 |
| NIBAN1 | niban apoptosis regulator 1 | 0.0250082 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0249665 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0248681 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0248259 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 0.0247804 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0246446 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0245292 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0245239 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.150783 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.138377 |
| VIM | vimentin | -0.0954297 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0923461 |
| PTMA | prothymosin, alpha | -0.0852212 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0833492 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0742564 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0701713 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0689382 |
| FOXP2 | forkhead box P2 | -0.0665044 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0640661 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0628584 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0589925 |
| THBS1 | thrombospondin 1 | -0.0553345 |
| PTK2 | protein tyrosine kinase 2 | -0.0537945 |
| HMGA2 | high mobility group AT-hook 2 | -0.0515101 |
| USP3 | ubiquitin specific peptidase 3 | -0.0514321 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0512953 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0501949 |
| GPC3 | glypican 3 | -0.0501479 |
| RPS16 | ribosomal protein S16 | -0.0497813 |
| RBM39 | RNA binding motif protein 39 | -0.0494687 |
| RLF | rearranged L-myc fusion | -0.049288 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0490932 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0475975 |
| CENPE | centromere protein E, 312kDa | -0.0473054 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0457621 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0435362 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0433979 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0429434 |
| COL3A1 | collagen, type III, alpha 1 | -0.0427907 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0426134 |
| RPL11 | ribosomal protein L11 | -0.0417754 |
| RPS27A | ribosomal protein S27a | -0.0415451 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0415064 |
| MATR3 | matrin 3 | -0.0412603 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0411235 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0404838 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0404568 |
| ZNF292 | zinc finger protein 292 | -0.0404005 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0400114 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0395302 |
| COL1A2 | collagen, type I, alpha 2 | -0.0390962 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0390365 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | -0.038562 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.038462 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0381422 |
| EMP1 | epithelial membrane protein 1 | -0.0376077 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0368367 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0367963 |
| DMD | dystrophin | -0.0365908 |
| GNAS | GNAS complex locus | -0.0365305 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0361348 |
| RPL37 | ribosomal protein L37 | -0.0357436 |
| SRPK2 | SRSF protein kinase 2 | -0.0349083 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0348184 |
| KIF5B | kinesin family member 5B | -0.0343814 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0343762 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0343031 |
| SMYD3 | SET and MYND domain containing 3 | -0.0342651 |
| CALR | calreticulin | -0.0342449 |
| PROS1 | protein S (alpha) | -0.0339433 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0339296 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0338667 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0338456 |
| RPLP1 | ribosomal protein, large, P1 | -0.0334251 |
| ZNF385D | zinc finger protein 385D | -0.0331008 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | -0.0330653 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0329442 |
| RPL30 | ribosomal protein L30 | -0.0328245 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.03282 |
| RPL26 | ribosomal protein L26 | -0.0326555 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0326094 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0324981 |
| NCAM2 | neural cell adhesion molecule 2 | -0.032427 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0320509 |
| VCL | vinculin | -0.0319269 |
| HDAC2 | histone deacetylase 2 | -0.0315984 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0314435 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0310071 |
| HMGB2 | high mobility group box 2 | -0.0309639 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0308948 |
| TTK | TTK protein kinase | -0.0307334 |
| WDR43 | WD repeat domain 43 | -0.0306477 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0306002 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | -0.0302675 |
| RPL35A | ribosomal protein L35a | -0.0302634 |
| MEF2C | myocyte enhancer factor 2C | -0.030229 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0301354 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0300211 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 | -0.0298998 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.029686 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0296489 |
| RFPL4B | ret finger protein-like 4B | -0.0295735 |
| TMSB4X | thymosin beta 4, X-linked | -0.0295431 |
| ABI2 | abl-interactor 2 | -0.0291309 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.0291185 |
| NPR2 | natriuretic peptide receptor 2 | -0.0290693 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.0290667 |
| PAXBP1 | PAX3 and PAX7 binding protein 1 | -0.029011 |
