| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rimonabant perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rimonabant_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.136851 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.11696 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.104258 |
| KYNU | kynureninase | 0.0788011 |
| PRELID2 | PRELI domain containing 2 | 0.072468 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0722893 |
| FLNA | filamin A, alpha | 0.0708072 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0660888 |
| FN1 | fibronectin 1 | 0.0600675 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0571421 |
| COL5A1 | collagen, type V, alpha 1 | 0.0551808 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0541311 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0535003 |
| C1D | C1D nuclear receptor corepressor | 0.0524854 |
| ATXN1 | ataxin 1 | 0.050585 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0502373 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0485749 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0485681 |
| PLEC | plectin | 0.0469467 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0466602 |
| CALU | calumenin | 0.0446196 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0442644 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0442078 |
| LOXL2 | lysyl oxidase-like 2 | 0.0439758 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0432675 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0420702 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0418723 |
| GLIS3 | GLIS family zinc finger 3 | 0.0414582 |
| NRP1 | neuropilin 1 | 0.0406691 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0401889 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0392697 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0386356 |
| MAP4 | microtubule-associated protein 4 | 0.0382535 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0374734 |
| PRKCA | protein kinase C, alpha | 0.0371965 |
| GOLGA3 | golgin A3 | 0.0370916 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0370741 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0370583 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0368716 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0367578 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0359785 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.034711 |
| DNAH11 | dynein, axonemal, heavy chain 11 | 0.0342523 |
| INTS6 | integrator complex subunit 6 | 0.0341301 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0340785 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0340272 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.033965 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0333814 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0332743 |
| CERT1 | ceramide transporter 1 | 0.0329144 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0328162 |
| ECE1 | endothelin converting enzyme 1 | 0.0324486 |
| CLTC | clathrin, heavy chain (Hc) | 0.0324086 |
| STC1 | stanniocalcin 1 | 0.0323893 |
| HDLBP | high density lipoprotein binding protein | 0.0320202 |
| JPH2 | junctophilin 2 | 0.0314088 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0313848 |
| VMP1 | vacuole membrane protein 1 | 0.0311466 |
| GOLGB1 | golgin B1 | 0.031089 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0309754 |
| RIGI | RNA sensor RIG-I | 0.0304626 |
| EGFR | epidermal growth factor receptor | 0.030364 |
| LOX | lysyl oxidase | 0.0301283 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0299015 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0297044 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0292874 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0292632 |
| HIP1 | huntingtin interacting protein 1 | 0.029161 |
| ANO10 | anoctamin 10 | 0.0288798 |
| GLG1 | golgi glycoprotein 1 | 0.0287163 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0287084 |
| RNF24 | ring finger protein 24 | 0.0286853 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0285998 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0285101 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0283599 |
| TRRAP | transformation/transcription domain-associated protein | 0.0282662 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0281532 |
| UBN2 | ubinuclein 2 | 0.0279044 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0279006 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0278817 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0277345 |
| DIAPH3 | diaphanous-related formin 3 | 0.0274232 |
| SQSTM1 | sequestosome 1 | 0.0271043 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0269294 |
| LOC112694756 | uncharaterized LOC112694756 | 0.026813 |
| AHR | aryl hydrocarbon receptor | 0.0267576 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0266251 |
| MYO1E | myosin IE | 0.0262598 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0260199 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0260141 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.025498 |
| EXOC4 | exocyst complex component 4 | 0.0253555 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0253037 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0252677 |
| GSE1 | Gse1 coiled-coil protein | 0.0251812 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0250577 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0249377 |
| STC2 | stanniocalcin 2 | 0.0247777 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0247037 |
| TJP1 | tight junction protein 1 | 0.0246491 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.163689 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0864429 |
| TMSB10 | thymosin beta 10 | -0.0797749 |
| PGK1 | phosphoglycerate kinase 1 | -0.0725221 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0704632 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0627559 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0625844 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0536649 |
| HLA-A | major histocompatibility complex, class I, A | -0.0503867 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0496402 |
| HLA-B | major histocompatibility complex, class I, B | -0.0475424 |
| VIM | vimentin | -0.0472229 |
| MEF2A | myocyte enhancer factor 2A | -0.0447473 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0436411 |
| COL5A2 | collagen, type V, alpha 2 | -0.0428572 |
| JMJD1C | jumonji domain containing 1C | -0.0425681 |
| CDH13 | cadherin 13 | -0.0418726 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0404813 |
| PTMA | prothymosin, alpha | -0.0404572 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.040351 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0378693 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0370886 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0365346 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0364728 |
| CAVIN1 | caveolae associated protein 1 | -0.0363969 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0362751 |
| MMP12 | matrix metallopeptidase 12 | -0.0361897 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.035826 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0354998 |
| S100A6 | S100 calcium binding protein A6 | -0.0346761 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0340957 |
| NRXN3 | neurexin 3 | -0.0335477 |
| VEGFC | vascular endothelial growth factor C | -0.0333688 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0321017 |
| SBF2 | SET binding factor 2 | -0.0319862 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0318974 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0317778 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0309295 |
| RPS27A | ribosomal protein S27a | -0.0308934 |
| ARRDC3 | arrestin domain containing 3 | -0.0307402 |
| GOLGA4 | golgin A4 | -0.0297451 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0292371 |
| RPL37A | ribosomal protein L37a | -0.0291861 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0287229 |
| CDC73 | cell division cycle 73 | -0.0286521 |
| KAZN | kazrin, periplakin interacting protein | -0.0282135 |
| DST | dystonin | -0.0276672 |
| RAI14 | retinoic acid induced 14 | -0.0275624 |
| RASA3 | RAS p21 protein activator 3 | -0.0272106 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0268811 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0264697 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 | -0.0261512 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0260278 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0257419 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0252389 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0251069 |
| CTNNBL1 | catenin, beta like 1 | -0.0250095 |
| B2M | beta-2-microglobulin | -0.0249237 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0248341 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0248285 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0247372 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0245642 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0243077 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0242934 |
| KIF16B | kinesin family member 16B | -0.0240689 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.024033 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0239667 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | -0.0239327 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0236764 |
| TMSB4X | thymosin beta 4, X-linked | -0.0235156 |
| NABP1 | nucleic acid binding protein 1 | -0.0233837 |
| ENO1 | enolase 1, (alpha) | -0.0233416 |
| RAB8B | RAB8B, member RAS oncogene family | -0.0233308 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0232963 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0232138 |
| COL3A1 | collagen, type III, alpha 1 | -0.0231361 |
| WDFY1 | WD repeat and FYVE domain containing 1 | -0.023018 |
| TMEM263 | transmembrane protein 263 | -0.0227577 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0226124 |
| USP37 | ubiquitin specific peptidase 37 | -0.0225823 |
| STK4 | serine/threonine kinase 4 | -0.0225541 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0225338 |
| JUN | jun proto-oncogene | -0.0224111 |
| YEATS2 | YEATS domain containing 2 | -0.0218303 |
| SPTY2D1 | SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) | -0.0217953 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0216837 |
| S100A10 | S100 calcium binding protein A10 | -0.0214617 |
| RPS8 | ribosomal protein S8 | -0.0212367 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0212296 |
| FAM162A | family with sequence similarity 162, member A | -0.0211455 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0210769 |
| SERINC3 | serine incorporator 3 | -0.0210751 |
| IGF2 | insulin-like growth factor 2 | -0.0210457 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0210212 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0209608 |
| NDRG1 | N-myc downstream regulated 1 | -0.0208877 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0208727 |
| TNNC1 | troponin C type 1 (slow) | -0.0207444 |
| TBC1D15 | TBC1 domain family, member 15 | -0.0206059 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0204902 |