| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rimonabant perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rimonabant_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EXT1 | exostosin glycosyltransferase 1 | 0.131034 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.1113 |
| NTN4 | netrin 4 | 0.101648 |
| FLNA | filamin A, alpha | 0.101147 |
| NDRG1 | N-myc downstream regulated 1 | 0.0812473 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0793117 |
| NRP1 | neuropilin 1 | 0.076902 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0751828 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0744812 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0692608 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0667625 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0653731 |
| GRB10 | growth factor receptor-bound protein 10 | 0.059915 |
| SEPTIN9 | septin 9 | 0.0571325 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0560471 |
| ASPH | aspartate beta-hydroxylase | 0.0551651 |
| SMAD3 | SMAD family member 3 | 0.0511811 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0505938 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0483692 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0482281 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0472373 |
| VCL | vinculin | 0.0463198 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0460064 |
| VEGFA | vascular endothelial growth factor A | 0.044775 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.043716 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0435218 |
| PLEC | plectin | 0.0433428 |
| GLIS3 | GLIS family zinc finger 3 | 0.0432554 |
| ACTN4 | actinin, alpha 4 | 0.0408446 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0407271 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0403676 |
| STC2 | stanniocalcin 2 | 0.0396355 |
| MLPH | melanophilin | 0.0395674 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0377701 |
| RASAL2 | RAS protein activator like 2 | 0.0366922 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0362852 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0360841 |
| RNF213 | ring finger protein 213 | 0.0356794 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0346108 |
| LOXL2 | lysyl oxidase-like 2 | 0.034501 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0336828 |
| RUNX2 | runt-related transcription factor 2 | 0.032913 |
| RAB31 | RAB31, member RAS oncogene family | 0.0328507 |
| KSR1 | kinase suppressor of ras 1 | 0.0325053 |
| ATXN1 | ataxin 1 | 0.0322255 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.032045 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0314929 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0300673 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.029967 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0293989 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0286487 |
| SDC2 | syndecan 2 | 0.0285221 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0279324 |
| ENAH | enabled homolog (Drosophila) | 0.0266467 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.026494 |
| FOSL2 | FOS-like antigen 2 | 0.0264193 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0263736 |
| CAB39 | calcium binding protein 39 | 0.0261497 |
| TGFB1 | transforming growth factor, beta 1 | 0.0259714 |
| MAP1B | microtubule-associated protein 1B | 0.0258054 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0256949 |
| VEGFC | vascular endothelial growth factor C | 0.0255919 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0255544 |
| RDH10 | retinol dehydrogenase 10 (all-trans) | 0.0254088 |
| SVIL | supervillin | 0.0254045 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0253279 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0248419 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0248335 |
| RBPMS | RNA binding protein with multiple splicing | 0.0247387 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0244136 |
| CORO1C | coronin, actin binding protein, 1C | 0.0243576 |
| ANKRD28 | ankyrin repeat domain 28 | 0.024339 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.024151 |
| TXNRD1 | thioredoxin reductase 1 | 0.0240812 |
| RNF145 | ring finger protein 145 | 0.0238264 |
| PALLD | palladin, cytoskeletal associated protein | 0.0234067 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | 0.0230633 |
| ATN1 | atrophin 1 | 0.0229887 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0228482 |
| FTL | ferritin, light polypeptide | 0.0228054 |
| CD44 | CD44 molecule (Indian blood group) | 0.0227736 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0226617 |
| FNDC3B | fibronectin type III domain containing 3B | 0.022581 |
| JAG1 | jagged 1 | 0.0225432 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0224528 |
| AOPEP | aminopeptidase O (putative) | 0.0223712 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0221216 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0221156 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0220387 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0220236 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.0216652 |
| NPTN | neuroplastin | 0.021628 |
| NXN | nucleoredoxin | 0.0215184 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0213068 |
| PKM | pyruvate kinase, muscle | 0.0211202 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0210154 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0209532 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0207257 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0206677 |
| AREG | amphiregulin | 0.020544 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.258608 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.220328 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.191715 |
| PTMA | prothymosin, alpha | -0.166378 |
| CANX | calnexin | -0.132112 |
| SQSTM1 | sequestosome 1 | -0.100243 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.091053 |
| S100A6 | S100 calcium binding protein A6 | -0.0832758 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0761644 |
| TMSB4X | thymosin beta 4, X-linked | -0.0735457 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0715815 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0712787 |
| NRG1 | neuregulin 1 | -0.0601639 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0582505 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0575286 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0566918 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0561205 |
| RPS27A | ribosomal protein S27a | -0.0538841 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0532184 |
| CEP350 | centrosomal protein 350kDa | -0.0519256 |
| ITGA1 | integrin, alpha 1 | -0.0517395 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0489971 |
| IER3 | immediate early response 3 | -0.0485056 |
| CALU | calumenin | -0.046593 |
| TMEM165 | transmembrane protein 165 | -0.0458156 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0448378 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0444023 |
| CADM1 | cell adhesion molecule 1 | -0.0443329 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0437382 |
| ENO1 | enolase 1, (alpha) | -0.0424432 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0419918 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0414026 |
| HLA-B | major histocompatibility complex, class I, B | -0.0411121 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0408913 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0404336 |
| CALR | calreticulin | -0.0400855 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0393544 |
| SUCO | SUN domain containing ossification factor | -0.0386875 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0386796 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0379427 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0373897 |
| RAI14 | retinoic acid induced 14 | -0.0369298 |
| GOLGA4 | golgin A4 | -0.0362307 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0361291 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0361033 |
| UBC | ubiquitin C | -0.0359207 |
| RPL34 | ribosomal protein L34 | -0.0358065 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.035531 |
| USP34 | ubiquitin specific peptidase 34 | -0.0354636 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0350691 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0345874 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0344641 |
| LRRC23 | leucine rich repeat containing 23 | -0.0344608 |
| TMEM263 | transmembrane protein 263 | -0.0343679 |
| RPL26 | ribosomal protein L26 | -0.0342931 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | -0.0340914 |
| TMSB10 | thymosin beta 10 | -0.0339435 |
| VIM | vimentin | -0.033693 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0335648 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.033535 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0335131 |
| FAM13A | family with sequence similarity 13, member A | -0.0334347 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0332798 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0331609 |
| RPS24 | ribosomal protein S24 | -0.0329861 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.032761 |
| PLIN2 | perilipin 2 | -0.0319889 |
| RPL31 | ribosomal protein L31 | -0.0317506 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0315222 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0314749 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0307344 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0304666 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0300114 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0299298 |
| CD109 | CD109 molecule | -0.0288818 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.028519 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.027867 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0278374 |
| EFNA5 | ephrin-A5 | -0.0276137 |
| RPL37A | ribosomal protein L37a | -0.0275904 |
| RSF1 | remodeling and spacing factor 1 | -0.0274754 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0273714 |
| TPR | translocated promoter region, nuclear basket protein | -0.027351 |
| LOX | lysyl oxidase | -0.0270225 |
| H1-0 | H1.0 linker histone | -0.0267599 |
| TPM4 | tropomyosin 4 | -0.0266734 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0266214 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0265598 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0265275 |
| NOP58 | NOP58 ribonucleoprotein | -0.0263564 |
| RPS25 | ribosomal protein S25 | -0.0262601 |
| MTDH | metadherin | -0.0261655 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0258252 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0252565 |
| HDLBP | high density lipoprotein binding protein | -0.0249186 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0247392 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0246729 |
| SRP72 | signal recognition particle 72kDa | -0.0245112 |
| RPL35A | ribosomal protein L35a | -0.0242727 |
| SBF2 | SET binding factor 2 | -0.0235393 |
