Ritonavir Gene Set

Dataset	DrugBank Drug Targets
Category	physical interactions
Type	drug
Description	A L-valine derivative in which the alpha-nitrogen of L-valinamide is substituted with a methyl{[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl}carbamoyl group and the amide nitrogen by a (2S,4S,5S)-4-hydroxy-1,6-diphenyl-5-{[(1,3-thiazol-5-ylmethoxy)carbonyl]amino}hexan-2-yl group. An antiretroviral drug from the protease inhibitor class used to treat HIV infection and AIDS, it is often used as a fixed-dose combination with another protease inhibitor, lopinavir. (Chemical Entities of Biological Interest Ontology, CHEBI_45409)
External Link	http://www.drugbank.ca/drugs/DB00503
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Genes

15 interacting proteins for the Ritonavir drug from the curated DrugBank Drug Targets dataset.

Symbol	Name
ABCB1	ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCG2	ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2
CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2C19	cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C8	cytochrome P450, family 2, subfamily C, polypeptide 8
CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6	cytochrome P450, family 2, subfamily D, polypeptide 6
CYP2E1	cytochrome P450, family 2, subfamily E, polypeptide 1
CYP3A5	cytochrome P450, family 3, subfamily A, polypeptide 5
CYP3A7	cytochrome P450, family 3, subfamily A, polypeptide 7
SLCO1A2	solute carrier organic anion transporter family, member 1A2
SLCO1B1	solute carrier organic anion transporter family, member 1B1